””’J‘Pr‚̃y[ƒW(Yoshitoshi Kasuya)

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2016

Fujita T, Yoshioka K, Umezawa H, Tanaka K, Naito Y, Nakayama T, Hatano M,Tatsumi K, Kasuya Y. Role of CD69 in the pathogenesis of elastase-induced pulmonary inflammationand emphysema. Biochem Biophys Rep. in press, 2016.

Hashimoto M, Murata K, Ishida J, Kanou A, Kasuya Y, Fukamizu A: Severe hypomyelination and developmental defects are caused in mice lacking protein arginine methyltransferase 1 (PRMT1) in the central nervous system. J Biol Chem, 291(5):2237-2245, 2016.

2015

Kim J, Park K, Ishida J, Kako K, Hamada J, Kani S, Takeuchi M, Namiki K, Fukui H, Fukuhara S, Hibi M, Kobayashi M, Kanaho Y, Kasuya Y, Mochizuki N, Fukamizu A: PRMT8 as a phospholipase regulates Purkinje cell dendritic arbors and motor coordination. Science Advances, Dec 4;1(11):e1500615, 2015 (doi: 10.1126/sciadv.1500615), 2015.

Kobayashi T, Tanaka K, Fujita T, Umezawa H, Amano H, Yoshioka K, Naito Y, Hatano M, Kimura S, Tatsumi K, Kasuya Y: Bidirectional role of IL-6 signal in pathogenesis of lung fibrosis. Respiratory Research, 2015 Aug 20;16:99 (14 pages). doi: 10.1186/s12931-015-0261-z, 2015.

Yoshioka K, Namiki K, Sudo T, Kasuya Y: p38alpha controls self-renewal and fate decision of neurosphere-forming cells in adult hippocampus. FEBS Open Bio, 5:437-44, 2015.

2014

Emoto N, Kasuya Y, Yanagisawa M: The Second Tomoh Masaki Award (2013). Life Sci, 24;118(2):87-90, 2014.

Naito Y, Yoshioka K, Tanaka K, Tatsumi K, Kimura S, Kasuya Y: Endothelin B receptor-mediated encephalopathic events in mouse sepsis model. Life Sci, 24;118(2):340-346, 2014.

Tanaka K, Yoshioka K, Tatsumi K, Kimura S, Kasuya Y: Endothelin regulates function of IL-17-producing T cell subset. Life Sci. 118(2):244-247, 2014.

Tanaka K, Fujita T, Umezawa H, Namiki K, Yoshioka K, Hagihara M, Sudo T, Kimura S, Tatsumi K, Kasuya Y: Therapeutic effect of lung mixed culture-derived epithelial cells on lung fibrosis. Laboratory Investigation, 94(11):1247-1259, 2014.

Amano H, Murata K, Matsunaga H, Tanaka K, Yoshioka K, Kobayashi T, Ishida J, Fukamizu A, Sugiyama F, Sudo T, Kimura S, Tatsumi K, Kasuya Y: p38 Mitogen-Activated Protein Kinase Accelerates Emphysema in Mouse Model of Chronic Obstructive Pulmonary Disease. J Recept Signal Transduct. 34(4):299-306, 2014.

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2012

Namiki K, Matsunaga H, Yoshioka K, Tanaka K, Murata K, Ishida J, Sakairi A, Kim J, Tokuhara N, Shibakawa N, Shimizu M, Wada Y, Tokunaga Y, Shigetomi M, Hagihara M, Kimura S, Sudo T, Fukamizu A, Kasuya Y: Mechanism for p38alpha-mediated experimental autoimmune encephalomyelitis. J. Biol. Chem. 287(29): 24228-24238, 2012.

Ishizaki S, Kasuya Y, Kuroda F, Tanaka K, Tsuyusaki J, Yamauchi K, Matsunaga H, Iwamura C, Nakayama T, Tatsumi K: Role of CD69 in acute lung injury. Life Sci. 90(17-18): 657-665, 2012.

2011

Tsuyusaki J, Kuroda F, Kasuya Y, Ishizaki S, Yamauchi K, Sugimoto H, Kono T, Iwamura C, Nakayama T, Tatsumi K: Cigarette smoke-induced pulmonary inflammation is attenuated in CD69-deficient mice. J . Receptor Signal Transduct. 31(6):434-439, 2011.

Yamauchi K, Kasuya Y, Kuroda F, Tanaka K, Tsuyusaki J, Ishizaki S, Matsunaga H, Iwamura C, Nakayama T, Tatsumi K: Attenuation of lung inflammation and fibrosis in CD69-deficient mice after intratracheal bleomycin. Respir. Res. Oct 5;12:131., 2011.

Tanaka Y, Takahashi H, Shibata S, Namiki K, Kimura S, Koike K, Kasuya Y: Functional analysis of guinea pig beta1-adrenoceptor. J Receptor Signal Transduct. 31(6):395-401, 2011.

2010

Tokuhara N, Namiki K, Uesugi M, Miyamoto C, Ohgoh M, Ido K, Yoshinaga T, Yamauchi T, Kuromitsu J, Kimura S, Miyamoto N, Kasuya Y: N-type calcium channel in the pathogenesis of experimental autoimmune encephalomyelitis J. Biol. Chem. 285(43):33294-33306, 2010.

2009

Miyamoto N, Namiki K, Tokuhara N, Uesugi M, Takahashi E, Kuromitsu J, Kasuya Y: The utilization of gene targeting models during in preclinical study of drug discovery process -Example of phenotypic and functional analysis of Cacna1b gene product- Curr. Pharmaceut. Biotech. 10(2):261-267, 2009.

2008

Yamagata K, Daitoku H, Takahashi Y, Namiki K, Hisatake K, Kako K, Mukai H, Kasuya Y, Fukamizu A: Arginine methylation of FOXO transcription factors inhibits their phosphorylation by Akt. Mol. Cell, 32(2):221-231, 2008.

Asada S, Ikeda A, Nagao R, Hama H, Sudo T, Fukamizu A, Kasuya Y, Kishi T: Oxidative stress-induced ubiquitination of RCAN1 mediated by SCF(beta-TrCP) ubiquitin ligase. Int. J. Mol. Med, 22(1): 95-104, 2008.

Furuya M, Ishida J, Inaba S, Kasuya Y, Kimura S, Nemori R, Fukamizu A: Impaired Placental Neovascularization in Mice with Pregnancy-Associated Hypertension. Laboratory Investigation, 88(4): 416-429, 2008.

2007

Hasegawa M, Furuya M, Kasuya Y, Nishiyama.M, Sugiura T. Nikaido T, .Momota Y, Ichinose M, Kimura S: The dynamics of CD151 might be crucial in carcinoma-stroma interaction by controlling integrins expression, adhesion strength and proteolytic activities. Laboratory Investigation, 87(9): 882-892, 2007.

Namiki K, Nakamura A, Furuya M, Mizuhashi S, Matsuo Y, Tokuhara N, Sudo T, Hama H, Kuwaki T, Yano S, Kimura S, Kasuya Y: Involvement of p38a mitgen-activated protein kinase in kainate-induced seizure and neuronal cell damage. J Receptor Signal Transduct. 27: 99-111, 2007.

Asada S, Matsuzaki H, Saito T, Sudo T, Mukai H, Iwashita S, Daitoku H, Kako K, Kishi T, Kasuya Y, Fukamizu A: Mitogen-activated protein kinases, Erk and p38, phosphorylate and regulate Foxo1. Cellular Signalling, 19(3):519-527, 2007.

2006

Matsuo Y*, Amano S*, Furuya M, Namiki K, Sakurai K, Nishiyama M, Sudo T, Tatsumi K, Kuriyama T, Kimura S, Kasuya Y: Involvement of p38alpha mitgen-activayed protein kinase in lung metastasis of tumor cells. J. Biol. Chem. 281, 36767-36775, 2006. (*The first two authors contributed equally to the work.)

Iemitsu M, Maeda S, Jesmin S, Otsuki T, Kasuya Y, Miyauchi T: Activation pattern of MAPK signaling in the hearts of trained and untrained rats following a single bout of exercise. J Applied Physiol. 101, 151-63, 2006.

2005

Furuya M, Nishiyama M, Kasuya Y, Kimura S, Ishikura H: Pathophysiology of Tumor Neovascularization. Vasc. Health Risk Management, I (4), 277-290, 2005.

Hashimoto Y, Ishida J, Yamamoto R, Fujiwara K, Asada S, Kasuya Y, Mochizuki N, Fukamizu A: G protein-coupled APJ receptor signaling induces focal adhesion formation and cell motility. Int. J. Mol. Med. 16, 787-792, 2005.

Momota Y, Suzuki N, Kasuya Y, Kobayashi T, Mizoguchi M, Yokoyama F, Nomizu M, Shinkai H, Iwasaki T, Utani A: Lamininα3 LG4 module induces keratinocyte migration: Involvement of matrix metalloproteinase-9. J. Receptors Signal Transduct. 25, 1-17, 2005.

Dateki M, Horii T, Kasuya Y, Mochizuki R, Nagao Y, Ishida J, Sugiyama F, Tanimoto K, Yagami K, Imai H, Fukamizu A: Neurochondrin negatively regulates CaMKII phosphorylation and nervous system specific gene disruption results in epileptic seizure. J. Biol. Chem. 280, 20503-20508, 2005.

Suyama T, Furuya M, Nishiyama M, Kasuya Y, Kimura S, Ichikawa T, Ueda T, Nikaido T, Ito H, Ishikura H: Up-Regulation of IFN-ƒÁ-Inducible Chemokine I-TAC and Mig, and Their Receptor CXCR3 in Human Renal Cell Carcinoma. Cancer, 103, 258-67, 2005.

2004

Sakurai K, Matsuoa Y, Sudoh T, Takuwa Y, Kimura S, Kasuya Y: Role of p38 mitogen-activated protein kinase in thrombus formation. J. Receptors Signal Transduct. 24, 283-296, 2004.

Amano S, Tatsumi K, Tanabe N, Kasahara Y, Kurosu K, Takiguchi Y, Kasuya Y, Kimura S, Kuriyama T: Polymorphism of the promoter region of prostacyclin synthase gene in chronic thromboembolic pulmonary hypertension. Respirology. 9, 184-189, 2004.

Ishida J, Hashimoto T, Hashimoto Y, Nishiwaki S, Iguchi T, Harada S, Sugaya T, Matsuzaki H, Yamamoto R, Shiota N, Okunishi H, Kihara M, Umemura S, Sugiyama F, Yagami K, Kasuya Y, Mochizuki N, Fukamizu A: Regulatory roles for APJ, a seven-transmembrane receptor related to AT1, in blood pressure in vivo. J. Biol. Chem. 279, 26274-26279, 2004.

Asada S, Takanami-Ohnishi Y, Zhou J, Hama H, Fukamizu A, Kimura S, Goto K, Kasuya Y: Cytodifferentiation enhances Erk activation induced by endothelin-1 in promary cultured astrocytes. J. Cardiovasc. Pharmacol. 44 (Suppl.1), S307-S312, 2004.

Irukayama-Tomobe Y, Miyauchi T, Kasuya Y, Sakai S, Goto K, Yamaguchi I: Activation of peroxisome proliferator-activated receptor-ƒ¿ (PPAR-ƒ¿) decreases endothelin-1-induced p38 mitogen-activated protein kinase (MAPK) activation in cardiomyocytes. J. Cardiovasc. Pharmacol. in press, 2004.

Irukayama-Tomobe Y, Miyauchi T, Sakai S, Kasuya Y, Ogata T, Takanashi M, Iemitsu M, Sudo T, Goto K, Yamaguchi I: Endothelin-1-induced cardiac hypertrophy is inhibited by activation of peroxisome proliferator-activated receptor-ƒ¿ partly via blockade of c-Jun NH2-terminal kinase pathway. Circulation 109, 904-910, 2004.

2003

Utani A, Momota Y, Endo H, Kasuya Y, Beck K, Suzuki N, Nomizu M and Shinkai H: Lamininƒ¿3 LG4 module induces matrix metalloproteinase-1 (MMP-1) through MAPK signaling. J Biol Chem. 278, 34483-34490, 2003.

Kayaba Y, Nakamura A, Kasuya Y, Ohuchi T, Yanagisawa M, Komuro I, Fukuda Y, Kuwaki T: Attenuated defense response and low basal blood pressure in orexin knockout mice. Am. J. Physiol. Regul. Integr. Comp. Physiol. 285, R581-R593, 2003.

Sato M, Moroi K, Nishiyama M, Zhou J, Usui H, Kasuya Y, Fukuda M, Kohara Y, Komuro I, Kimura S: Characterization of a novel C. elegans RGS protein with a C2 domain - Evidence for interaction between C2 domain and Galfaq subunit - Life Sci. 73, 917-932, 2003.

2002

Takanami-Ohnishi Y*, Amano S*, Kimura S, Asada S, Utani A, Maruyama M, Osada H, Tsunoda H, Irukayama-Tomobe Y, Goto K, Karin M, Sudo T, Kasuya Y: Essential role of p38 mitogen-activated protein kinase in contact hypersensitivity. J. Biol. Chem. 277, 37896-37903, 2002. (*The first two authors contributed equally to the work.)

2001

Takanami-Ohnishi Y, Asada S, Tsunoda H, Fukamizu A, Goto K, Yoshikawa H, Kubo T, Sudo T, Kimura S, Kasuya Y: Possible involvement of p38 mitogen-activated protein kinase in decidual function in parturition. Biochem. Biophys. Res. Commun. 288: 1155-1161, 2001.

2000

Yanai K, Saito T, Kakinuma Y, Kon Y, Hirota K, Taniguchi-Yanai K, Nishijo N, Shigematsu Y, Horiguchi H, Kasuya Y, Sugiyama F, Yagami K, Murakami K, Fukamizu A: Renin-dependent cardiovascular functions and renin-independent blood-brain barrier functions revealed by renin-deficient mice., J. Biol. Chem. 275: 5-8, 2000.

Maruyama M, Sudo T, Kasuya Y, Siga T, Hu BR, Osada H: Immunolocalization of p38 MAPK in mouse brain. Brain Res. 887: 350-358, 2000.

1999

Le-Niculescu H, Bonfoco E, Kasuya Y, Claret F-X, Green DR, Karin M: Withdrawal of survival factors results in activation of the JNK pathway in neuronal cells leading to Fas ligand induction and cell death., Mol. Cell. Biol. 19: 751-763, 1999.

Ishida J, Asada S, Daitoku H, Fujiwara K, Kon Y, Murakami K, Nakajima T, Kasuya Y, Fukamizu A: Expression and characterization of mouse angiotensin II type 1a receptor tagging hemagglutinin epitope in culture cells., Int. J. Mol. Med. 3: 263-270, 1999.

Namiki S, Kaneda F, Ikegami M, Arai T, Fujimori K, Asada S, Hama H, Kasuya Y, Goto K: Bis-N-nitroso-caged nitric oxides: Photochemistry and biological performance test by rat aorta vasorelaxation., Bioorganic & Medic. Chem. 7: 1695-1702, 1999.

Asada S, Kasuya Y, Hama H, Masaki T, Goto K: Cytodifferentiation potentiates aFGF-induced p21ras/Erk signaling pathway in rat cultured astrocytes. Biochem. Biophys. Res. Commun. 260: 441-445, 1999.

Kakinuma Y, Hama H, Kasuya Y, Fukamizu A: A new aspect of renin-angiotensin system (RAS) in central nervous system -RAS indispensable for maintaining function of Astrocytes-, Recent Research Developments in Neurochemistry, 2: 473-493, 1999.

1998

Uesugi M, Kasuya Y, Hayashi K, Goto K: SB209670, a potent endothelin receptor antagonist, prevents axonal degeneration after spinal cord injury., Brain Res. 786:235-239, 1998.

1997

Hama H, Kasuya Y, Sakurai T, Yamada G, Suzuki N, Masaki T, Goto K: Role of Endothelin-1 in Astrocyte Responses after Acute Brain Damage., J. Neurosci. Res. 47, 590-602, 1997.

Wei S, Kasuya Y, Yanagisawa M, Kimura S, Masaki T, Goto K: Studies on endothelium-dependent vasorelaxation by hydralazine in porcine coronary artery., Eur. J. Pharmacol. 301, 307-314, 1997.

Ozawa F, Kasuya Y, Hama H, Asada S, Inada T, Masaki T, Goto K: Microtubule dynamics regulates the level of endothelin-B receptor in rat cultured astrocytes., J. Neurochem. 69, 562-569, 1997.

Koyama K, Kasuya Y, Koyama K, Goto K: Nitric oxide-mediated vasorelaxation induced by sodium polyoxyethylene laurylether sulfate., Toxicol. Appl. Pharmacol. 145, 294-300, 1997.

Goto K, Hama H, Kasuya Y: Molecular pharmacology and pathological significance of endothelin., Jpn. J. Pharmacol. 72, 261-290, 1997.

1996

Sakai S, Miyauchi T, Sakurai T, Kasuya Y, Ihara M, Yamaguchi I, Goto K, Sugishita Y: Endogenous endothelin-1 participates in the maintenance of cardiac function in rats with congestive heart failure. -Marked increase in endothelin-1 production in the failing heart-, Circulation 93, 1214-1222, 1996.

Uesugi M, Kasuya Y, Hama H, Yamamoto M, Hayashi K, Masaki T, Goto K: Endogenous endothelin-1 initiates astrocytic growth after spinal cord injury., Brain Res. 728, 255-259, 1996.

1995

Takigawa M, Sakurai T, Kasuya Y, Abe Y, Masaki T, Goto K: Molecular characterization of guanine-nucleotide-binding regulatory proteins which couple to endothelin receptors., Eur. J. Biochem. 228, 102-108, 1995.

Yamada G, Hama H, Kasuya Y, Masaki T, Goto K: Possible sources of endothelin-1 in damaged rat brain., J. Cardiovasc. Pharmacol. 26 (Suppl.), 486-490, 1995.

Asada S, Kasuya Y, Sakurai T, Masaki T, Goto K: ET-1-induced down-regulation of ETB receptor mRNA: participation of cAMP., J. Cardiovasc. Pharmacol. 26 (Suppl.), 272-275, 1995.

Sakai S, Yorikane R, Miyauchi T, Sakurai T, Kasuya Y, Yamaguchi I, Sugishita Y, Goto K: Altered production of endothelin-1 in the hypertrophied rat heart. J. Cardiovasc. Pharmacol. 26 (Suppl.), 452-455,1995.

Miyauchi T, Sakai S, Ihara M, Kasuya Y, Yamaguchi I, Goto K, Sugishita Y. Increased endothelin-1 binding sites in the cardiac membranes in rats with chronic heart failure., J. Cardiovasc. Pharmacol. 26 (Suppl.), 448-451,1995.@

1994

Sakurai T, Abe Y, Kasuya Y, Takuwa N, Shiba R, Yamashita T, Endo T, Goto K: Activin A stimulates mitogenesis in Swiss 3T3 fibroblasts without the activation of mitogen-activated protein kinases., J. Biol. Chem. 269, 14118-14122, 1994.

Yasuda N, Kasuya Y, Yamada G, Hama H, Masaki T, Goto K: Loss of contractile activity of endothelin-1 induced by electrical field stimulation-generated free radicals., Br. J. Pharmacol. 113, 21-28, 1994.

Kasuya Y, Abe Y, Hama H, Sakurai T, Asada S, Masaki T, Goto K: Endothelin-1 activates mitogen-activated protein kinases through two independent signaling pathways in rat astrocytes., Biochem. Biophys. Res. Commun. 204, 1325-1333, 1994.

1993

Masaki T, Kasuya Y, Goto K: Endothelin in regulation of vascular tone., Atherosclerosis Reviews 25: 111-118, 1993.

1992

Sakurai T, Morimoto H, Kasuya Y, Takuwa Y, Nakauchi H, Masaki T, Goto K: Level of ETB receptor mRNA is down-regulated by endothelins through decreasing the intracellular stability of mRNA molecules., Biochem. Biophys. Res. Commun. 186, 342-347, 1992.

Hama H, Sakurai T, Kasuya Y, Fujiki M, Masaki T, Goto K: Action of endothelin-1 on rat astrocyte through ETB receptor., Biochem. Biophys. Res. Commun. 186, 355-362, 1992.

Kasuya Y, Takuwa Y, Yanagisawa M, Masaki T, Goto K: A pertussis toxin-sensitive mechanism of endothelin action in porcine coronary artery smooth muscle., Br. J. Pharmacol. 107, 456-462, 1992.

Noguchi J, Yanagisawa M, Imamura M, Kasuya Y, Sakurai T, Tanaka T, Masaki T: Complete primary structure and tissue expression of chicken pectralis M-protein., J. Biol. Chem. 267, 20302-20310, 1992.

1991

Sawamura T, Kasuya Y, Matsushita Y, Suzuki N, Shinmi O, Kishi N, Sugita Y, Yanagisawa M, Goto K, Masaki T, Kimura S: Phosphoramidon inhibits the intracellular conversion of big endothelin-1 to endothelin-1 in cultured endothelial cells., Biochem. Biophys. Res. Commun. 174, 779-784, 1991

Abe Y, Kasuya Y, Kudo M, Yamashita K, Goto K, Masaki T, Takuwa Y: Endothelin-1-induced phosphorylation of the 20 KDa myosin light chain and caldesmon in porcine coronary artery smooth muscle., Jpn. J. Pharmacol. 57, 431-435, 1991.

Masaki T, Kasuya Y, Yanagisawa M, Goto K: A hypothesis for mechanism of endothelin-induced vasoconstriction., Ion channels of vascular smooth muscle cells and endothlial cells. edited by H.Kuriyama: pp209-215, 1991.

1990

Takuwa Y, Kasuya Y, Takuwa N, Kudo M, Yanagisawa M, Goto K, Masaki T: Endothelin receptor is coupled to phospholipase C via a pertussis toxin-insensitive guanine nucleotide-binding regulatory protein in vascular smooth muscle cells., J. Clin. Invest. 85, 653-658, 1990.

Masaki T, Yanagisawa M, Takuwa Y, Kasuya Y, Kimura S, Goto K: Cellular mechanism of vasoconstriction induced by endothelin., Advances in Second Messanger and Phosphoprotein Research (The Biology and Medicine of Signal Transduction) edited by Y. Nishizuka vol. 24 pp425-428, 1990.

1989

Inoue A, Yanagisawa M, Kimura S, Kasuya Y, Miyauchi T, Goto K, Masaki T: The human endothelin family: Three structurally and pharmacological distinct isopeptides predicted by three separate genes., Proc. Natl. Acad. Sci. USA 86, 2863-2867, 1989.

Goto K, Kasuya Y, Matsuki N, Takuwa Y, Kurihara H, Ishikawa T, Kimura S, Yanagisawa M, Masaki T: Endothelin activates the dihydropyridine-sensitive, voltage-dependent Ca2+ channel in vascular smooth muscle., Proc. Natl. Acad. Sci. USA 86, 3915-3918, 1989.

Kasuya Y, Takuwa Y, Yanagisawa M, Kimura S, Goto K, Masaki T: Endothelin-1 induces vasoconstriction through two functionally distinct pathways in porcine coronary artery: Contribution of phosphoinositide turnover., Biochem. Biophys. Res. Commun. 161, 1049-1055, 1989.

Kasuya Y, Ishikawa T, Yanagisawa M, Kimura S, Goto K, Masaki T: Mechanism of contraction to endothelin in isolated porcine coronary artery., Am. J. Physiol. 257, H1828-H1835, 1989.

1988

Yanagisawa M, Inoue A, Ishikawa T, Kasuya Y, Kimura S, Kumagaye S, Nakajima K, Watanabe T-X, Sakakibara S, Goto K, Masaki T: Primary structure, synthesis, and biological activity of rat endothelin, an endothelium-derived vasoconstrictor peptide., Proc. Natl. Acad. Sci. USA 85, 6964-6967, 1988.

Kimura S, Kasuya Y, Sawamura T, Shinmi O, Sugita Y, Yanagisawa M, Goto K, Masaki T: Structure-activity relationships of endothelin: Importance of the C-terminal., Biochem. Biophys. Res. Commun. 156, 1182-1186, 1988.

Kimura S, Kasuya Y, Sawamura T, Shinmi O, Sugita Y, Yanagisawa M, Goto K, Masaki T: Conversion of big endothelin-1 to 21-residue endothelin-1 is essential for expression of full vasoconstrictor activity: Structure-activity relationships of big endothelin-1., J. Cardiovasc. Pharmacol. 13 (Suppl.), 5-7, 1988.

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3. Masaki T, Yanagisawa M, Takuwa Y, Kasuya Y, Kimura S, Goto K (1990) Cellular mechanism of vasoconstriction induced by endothelin. Advances in Second Messanger and Phosphoprotein Research (The Biology and Medicine of Signal Transduction) edited by Nishizuka Y, Academic Press, London, 24, 425-428, 1990.

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16. ˆ¢•”—zˆê˜YA””’J‘PrF ƒGƒ“ƒhƒZƒŠƒ“Žó—e‘́^¶—“I–ðŠ„C “ú–{—Տ° 57 (7)F252-259, 1998.

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