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原著論文
2011
Matsuzaki N, Nishiyama M, Song D, Moroi K, Kimura S: Potent and selective inhibition of angiotensin AT1 receptor signalling by RGS2: Roles of its N-terminal domain. Cellular Signalling, 23(6):1041-1049, 2011.
2007
Moroi K, Nishiyama M, Kawabata S, Ichiba H, Yajima T, Kimura S: Phosphorylation of Ser166 in RGS5 by protein kinase C causes loss of RGS function. Life Sciences. 81(1): 40-50, 2007.
2005
Lee MJ, Tasaki T, Moroi K, An JY, Kimura S, Davydov IV, Kwon YT: RGS4 and RGS5 are in vivo substrates of the N-end rule pathway. Proc. Natl. Acad. Sci. USA 102:15030-15035, 2005.
2003
Sato M, Moroi K, Nishiyama M, Zhou J, Usui H, Kasuya Y, Fukuda M, Kohara Y, Komuro I, Kimura S: Characterization of a novel C. elegans RGS protein with a C2 domain - Evidence for interaction between C2 domain and Galfaq subunit - Life Sciences, i73: 917-932, 2003.
2001
Zhou J, Moroi K, Nishiyama M, Usui H, Seki N, Ishida J, Fukamizu A, Kimura S: Characterization of RGS5 in regulation of G protein-coupled receptor signaling. Life Sciences, 68, 1457-1469, 2001.
2000
Usui H, Nishiyama M, Moroi K, Shibasaki T, Zhou J, Ishida J, Fukamizu A, Haga T, Sekiya S, Kimura S: RGS domain in the amino-terminus of G protein-coupled receptor kinase 2 inhibits Gq-mediated signaling. Int J Mol Med, 5, 335-340, 2000.
1999
Shibasaki T, Moroi K, Nishiyama M, Zhou J, Sakamoto A, Masaki T, Ito K, Haga T, Kimura S: Characterization of the carboxyl terminal-truncated endothelin B receptor coexpressed with G protein-coupled receptor kinase 2. Biochem Mol Biol Int, 47, 569-577, 1999.
1998
Moroi K, Ozaki N, Kadota T, Kadota K: Characterization of [3H]5-hydroxytryptamine and [3H]spiperone binding sites in clathrin-coated vesicles from bovine brain. Brain Res, 794, 291-298, 1998.
Tanaka H, Moroi K, Iwai J, Takahashi H, Ohnuma N, Hori S, Takimoto M, Nishiyama M, Masaki T, Yanagisawa M, Sekiya S, Kimura S: Novel mutations of the endothelin B receptor gene in patients with Hirschsprung's disease and their characterization. J Biol Chem, 273, 11378-1183, 1998.
1997
Mizuguchi T, Nishiyama M, Moroi K, Tanaka H, Saito T, Masuda Y, Masaki T, de Wit D, Yanagisawa M, Kimura S: Analysis of two pharmacologically predicted endothelin B receptor subtypes by using the endothelin B receptor gene knockout mouse. Br J Pharmacol, 120, 1427-1430, 1997.
1996
Kadota T, Yamaai T, Saito Y, Akita Y, Kawashima S, Moroi K, Inagaki N, Kadota K: Expression of dopamine transporter at the tips of growing neurites of PC12 cells. J Histochem Cytochem, 44, 989-996, 1996.
Shan LH, Nishiyama M, Shibasaki T, Moroi K, Goto K, Masaki T, Kimura S: Endothelin ETA and ETB receptors mediate endothelin-1-induced apamin-sensitive relaxation in the guinea pig ileum. Jpn J Pharmacol, 70, 259-267, 1996.
1995
Yorimitsu K, Moroi K, Inagaki N, Saito T, Masuda Y, Masaki T, Seino S, Kimura S: Cloning and sequencing of a human endothelin converting enzyme in renal adenocarcinoma (ACHN) cells producing endothelin-2. Biochem Biophys Res Commun, 208, 721-727, 1995.
Nishiyama M, Shan LH, Moroi K, Masaki T, Kimura S: Heterogeneity of endothelin ETA receptor-mediated contractions in the rabbit saphenous vein. Eur J Pharmacol, 286, 209-212, 1995.
Nishiyama M, Moroi K, Shan LH, Yamamoto M, Takasaki C, Masaki T, Kimura S: Two different endothelin B receptor subtypes mediate contraction of the rabbit saphenous vein. Jpn J Pharmacol, 68, 235-243, 1995.
Kadota T, Yamaai T, Saitoh Y, Kawashima S, Moroi K, Kadota K: Expression of a dopamine transporter in PC12h cells: an immunohistochemical study with an antipeptide antibody. Kaibogaku Zasshi, 70, 248-251, 1995.
1994
Ozaki N, Moroi K, Kadota T, Suzuki S, Kadota K: Dopamine D1 and D2 receptors and their signal system present in coated vesicles prepared from bovine striatal tissue. J Neurochem, 62, 582-91, 1994.
1993
Kadota T, Mizote M, Moroi K, Ozaki N, Kadota K: Rapid recovery of structure and function of the cholinergic synapses in the cat superior cervical ganglion in vivo following stimulation-induced exhaustion. Neurocytol, 22, 743-752, 1993.
Shinmi O, Yorimitsu K, Moroi K, Nishiyama M, Sugita Y, Saito T, Inagaki Y, Masaki T, Kimura S: Endothelin-2-converting enzyme from human renal adenocarcinoma cells is a phosphoramidon-sensitive, membrane-bound metalloprotease. J Cardiovasc Pharmacol, 22(Suppl 8), S61-S64, 1993.
1992
Kadota T, Fujita M, Moroi K, Kadota K: Localization of a 82 kDa protein in postsynaptic density and its association with cytoskeletons. Neurosci Res, 15, 124-129, 1992.
Yorimitsu K, Shinmi O, Nishiyama M, Moroi K, Sugita Y, Saito T, Inagaki Y, Masaki T, Kimura S: Effect of phosphoramidon on big endothelin-2 conversion into endothelin-2 in human renal adenocarcinoma (ACHN) cells. Analysis of endothelin-2 biosynthetic pathway. FEBS Lett, 314, 395-358, 1992.
1991
Moroi K, Kuga T, Kadota K: Bovine brain coated vesicles contain guanine nucleotide regulatory proteins. Jpn J Pharmacol, 55, 399-402, 1991.
1990
Kanisawa M, Suzuki S, Moroi K: The mode of action of ochratoxin A in acute enteritis in rats. J Environ Pathol Toxicol Oncol, 10, 56-63, 1990.
1989
Moroi K, Kuga T, Kadota K: Detection and characterization of 3H-clonidine binding sites in coated vesicles isolated from bovine brain. Jpn J Pharmacol, 51, 128-131, 1989.
1988
Moroi K, Takashi K, Kuga T: Involvement of GABAergic systems and benzodiazepine receptors in the jumping behavior induced by harmine and apomorphine in rats. Jpn J Pharmacol, 47, 367-378, 1988.
1987
Hsu LL, Moroi K, Lakchaura BD, Chan T, Lin CT, Wu JY: Monoclonal antibodies to a brain dopamine binding protein: production, specificity, and immunohistochemistry. Neurosci Res, 17, 417-423, 1987.
Moroi K, Kuga T: Estimation of harmine and its derivatives by HPLC: correlation of brain harmine levels with jumping behavior in rats. Jpn J Pharmacol, 43, 33-41, 1987.
1985
Moroi K, Hsu LL: Effects of phospholipids on the specific binding of [3H]spiroperidol to the cholate extract of rat brain synaptic membranes. Int J Biochem, 17, 637-644, 1985.
Moroi K, Suzuki S, Kuga T, Yamazaki M, Kanisawa M: Reduction of ochratoxin A toxicity in mice treated with phenylalanine and phenobarbital. Toxicol Lett, 25, 1-5, 1985.
1984
Moroi K, Hsu LL: A brain synaptic dopamine-binding protein: isolation and partial characterization. J Neurosci Res, 12, 113-128, 1984.
1982
Moroi K, Kuga T: Dual effects of tetrachlorvinphos on procaine toxicity and procainesterase activity in rats. Jpn J Pharmacol, 32, 109-120, 1982.
Moroi K, Kuga T: Inhibitory effect of leptophos on carboxylesterase (isocarboxazid amidase) in rat liver. Toxicol Lett, 11, 81-85, 1982.
1980
Moroi K, Kuga T: Isocarboxazid metabolism in vitro by liver microsomal carboxylesterase of monkey. Biochem Pharmacol, 29, 1491-1496, 1980.
1979
Ishitani R, Kin H, Kuwae T, Moroi K, Satoh T: Partial purification and immunological aspects of carboxylesterase from rat liver microsomes. Jpn J Pharmacol, 29, 413-421, 1979.
1977
Satoh T, Moroi K: Effect of pretreatment with tricresylphosphates and phenobarbital on the metabolism and toxicity of procaine in rats. Jpn J Pharmacol, 27, 233-237, 1977.
1976
Moroi K, Ushiyama S, Satoh T, Kuga T: Enzyme induction by repeated adminstration of tetrachlorvinphos in rats. Toxicol Appl Pharmacol, 37, 377-386, 1976.
1975
Moroi K, Sato T: Comparison between procaine and isocarboxazid metabolism in vitro by a liver microsomal amidase-esterase. Biochem Pharmacol, 24, 1517-1521, 1975.
1973
Sato T, Moroi K: Species differences in induction and inhibition of liver isocarboxazid hydrolase. Life Sci, 12, 169-176, 1973.
Sato T, Moroi K: Comparative studies on the inhibition of liver amidases, aminopeptidase and serum cholinesterases by EPN. Toxicol Appl Pharmacol, 25, 553-539, 1973.
1972
Sato T, Yamamoto S, Moroi K: The metabolism and placental transfer of isocarboxazid in pregnant rats. Jpn J Pharmacol, 22, 629-633, 1972.
Satoh T, Moroi K: Solubilization, purification and properties of isocarboxazid hydrolase from guinea pig liver. Biochem Pharmacol, 21, 3111-3120, 1972.
1971
Satoh T, Moroi K: Enzymatic hydrolysis of isocarboxazid by rat tissues. Biochem Pharmacol, 20, 504-507, 1971.
Sato T, Moroi K: Species and age differences in the activity of isocarboxazid hydrolysing enzyme. Arch Int Pharmacodyn Ther, 192, 128-134, 1971.
1970
Satoh T, Moroi K: Suppression of tryptophan pyrrolase induction in porphyric animals. Experientia, 26, 36-37, 1970.
1969
Sato T, Moroi K: Inhibition of tryptophan pyrrolase of rats by phenols, tryptophan analogs and hydrazine derivatives. Chem Pharm Bull (Tokyo), 17, 1560-1563, 1969.