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Home > 業績紹介
業績紹介


2010年教室業績
1. Tsuyuguchi T, Sakai Y, Sugiyama H, Miyakawa K, Ishihara T, Ohtsuka M, Miyazaki M, Yokosuka O Endoscopic diagnosis of intraductal papillary mucinous neoplasm of the bile duct.  J Hepatobiliary Pancreat Sci. 2010 May;17(3):230-5. Epub 2009 Aug 11.
2. Nakamoto S, Sakai Y, Kasanuki J, Kondo F, Ooka Y, Kato K, Arai M, Suzuki T, Matsumura T, Bekku D, Ito K, Tanaka T, Yokosuka O. Indications for the use of endoscopic mucosal resection for early gastric cancer in Japan: a comparative study with endoscopic submucosal dissection.  Endoscopy. 2009 Sep;41(9):746-50. Epub 2009 Aug 13.
3. Sakai Y, Tsuyuguchi T, Ishihara T, Yukisawa S, Sugiyama H, Miyakawa K, Kuroda Y, Yamaguchi T, Ozawa S, Yokosuka O. Long-term prognosis of patients with endoscopically treated postoperative bile duct stricture and bile duct stricture due to chronic pancreatitis. J Gastroenterol Hepatol. 2009 Jul;24(7):1191-7.
4. Yan J, Yamaguchi T, Odaka T, Suzuki T, Ohyama N, Hara T, Sudo K, Nakamura K, Denda T, Takiguchi N, Yokosuka O, Nomura F. Stool antigen test is a reliable method to detect Helicobacter pylori in the gastric remnant after distal gastrectomy for gastric cancer. J Clin Gastroenterol. 2010 Jan;44(1):73-4.
5. Fujimoto T, Tomizawa M, Yokosuka O. SiRNA of frizzled-9 suppresses proliferation and motility of hepatoma cells. Int J Oncol. 2009 Oct;35(4):861-6
6. Kuroda Y, Tsuyuguchi T, Sakai Y, K C S, Ishihara T, Yamaguchi T, Saisho H, Yokosuka O. Long-term follow-up evaluation for more than 10 years after endoscopic treatment for postoperative bile duct strictures. Surg Endosc. 2010 Apr;24(4):834-40.
7. Sakai Y, Tsuyuguchi T, Ishihara T, Sugiyama H, Miyakawa K, Yukisawa S, Yasui S, Eto R, Fujimoto T, Kaiho T, Miyazaki M, Yokosuka O. The usefulness of endoscopic transpapillary procedure in post-cholecystectomy bile duct stricture and post-cholecystectomy bile leakage.  Hepatogastroenterology. 2009 Jul-Aug;56(93):978-83.
8. Ohno I, Eibl G, Odinokova I, Edderkaoui M, Damoiseaux RD, Yazbec M, Abrol R, Goddard WA 3rd, Yokosuka O, Pandol SJ, Gukovskaya AS.  Rottlerin stimulates apoptosis in pancreatic cancer cells through interactions with proteins of the Bcl-2 family. Am J Physiol Gastrointest Liver Physiol. 2010 Jan;298(1):G63-73. Epub 2009 Sep 17.
9. Maruyama H, Takahashi M, Ishibashi H, Okabe S, Yoshikawa M, Yokosuka O. Changes in tumor vascularity precede microbubble contrast accumulation deficit in the process of dedifferentiation of hepatocellular carcinoma.  Eur J Radiol. 2010 Jul;75(1):e102-6. Epub 2009 Sep 23.
10. Nagao Y, Matsuoka H, Seike M, Yamasaki K, Kato J, Nakajima T, Miyazaki Y, Ohno T, Inuzuka S, Ohira H, Yokosuka O, Yatsuhashi H, Mori T, Honda K, Kawaguchi T, Ide T, Sata M.  Knowledge of Vibrio vulnificus infection among Japanese patients with liver diseases: a prospective multicenter study.    Med Sci Monit. 2009 Oct;15(10):PH115-120.
11. Kanda T, Gauss-Müller V, Cordes S, Tamura R, Okitsu K, Shuang W, Nakamoto S, Fujiwara K, Imazeki F, Yokosuka O. Hepatitis A virus (HAV) proteinase 3C inhibits HAV IRES-dependent translation and cleaves the polypyrimidine tract-binding protein.  J Viral Hepat. 2010 Sep;17(9):618-23. Epub 2009 Nov 2.
12. Hamano Y, Aoki T, Shirai R, Hatano M, Kimura R, Ogawa M, Yokosuka O, Ueda S. Low-dose darbepoetin alpha attenuates progression of a mouse model of aristolochic acid nephropathy through early tubular protection. Nephron Exp Nephrol.. 2010;114(2):e69-81.Epub 2009 Nov 7
13. Takeda S, Sato T, Katsuno T, Nakagawa T, Noguchi Y, Yokosuka O, Saito Y. Adsorptive depletion of alpha4 integrin(hi)- and CX3CR1hi-expressing proinflammatory monocytes in patients with ulcerative colitis.  Dig Dis Sci. 2010 Jul;55(7):1886-95. Epub 2009 Nov 12.
14. Nakamoto S, Imazeki F, Fukai K, Fujiwara K, Arai M, Kanda T, Yonemitsu Y, Yokosuka O. Association between mutations in the core region of hepatitis C virus genotype 1 and hepatocellular carcinoma development. J Hepatol. 2010 Jan;52(1):72-8. doi: 10.1016/j.jhep.2009.10.001. Epub 2009 Oct 23. Erratum in: J Hepatol. 2010 Apr;52(4):620.
15. Mukaide M, Tanaka Y, Shin-I T, Yuen MF, Kurbanov F, Yokosuka O, Sata M, Karino Y, Yamada G, Sakaguchi K, Orito E, Inoue M, Baqai S, Lai CL, Mizokami M. Mechanism of entecavir resistance of hepatitis B virus with viral breakthrough as determined by long-term clinical assessment and molecular docking simulation. Antimicrob Agents Chemother. 2010 Feb;54(2):882-9. Epub 2009 Nov 23.
16. Kanai F, Omata M, Yokosuka O. [Current status and future perspective of molecular targeted therapy for hepatocellular carcinoma]. Nihon Shokakibyo Gakkai Zasshi. 2009 Dec;106(12):1727-35. Review. Japanese.
17. Matsumura T, Arai M, Yonemitsu Y, Maruoka D, Tanaka T, Suzuki T, Yoshikawa M, Imazeki F, Yokosuka O.  The traditional Japanese medicine Rikkunshito increases the plasma level of ghrelin in humans and mice. J Gastroenterol. 2010 Mar;45(3):300-7. Epub 2009 Dec 10.
18. Maruyama H, Okugawa H, Kobayashi S, Yoshizumi H, Yokosuka O.  Pre-treatment hemodynamic features involved with long-term survival of cirrhotic patients after embolization of gastric fundal varices.  Eur J Radiol. 2010 Aug;75(2):e32-7.  Epub 2009 Dec 8.
19. Sakai Y, Tsuyuguchi T, Ishihara T, Sugiyama H, Eto R, Fujimoto T, Yasui S, Tamura R, Togo S, Tada M, Yokosuka O.  Cholangiopancreatography troubleshooting: the usefulness of endoscopic retrieval of migrated biliary and pancreatic stents.   Hepatobiliary Pancreat Dis Int. 2009 Dec;8(6):632-7.
20. Sakai Y, Tsuyuguchi T, Ishihara T, Sugiyama H, Miyakawa K, Yasui S, Eto R, Fujimoto T, Shimizu H, Miyazaki M, Yokosuka O. The successful use of peroral cholangioscopy for the diagnosis and treatment of the biliary tract lesions and giant bile duct stones in a 76-year-old man.  Surg Laparosc Endosc Percutan Tech. 2009 Dec;19(6):e237-40.
21. Mimura N, Tsujimura H, Ise M, Sakai C, Kojima H, Fukai K, Yokosuka O, Takagi T, Kumagai K.  [Hepatitis B virus reactivation after cessation of prophylactic lamivudine therapy in B-cell lymphoma patients treated with rituximab combined CHOP therapy]. Rinsho Ketsueki. 2009 Dec;50(12):1715-9. Japanese.
22. Ito K, Arai M, Imazeki F, Yonemitsu Y, Bekku D, Kanda T, Fujiwara K, Fukai K, Sato K, Itoga S, Nomura F, Yokosuka O. Risk of hepatocellular carcinoma in patients with chronic hepatitis B virus infection.  Scand J Gastroenterol. 2010;45(2):243-9.
23. Sakai Y, Ishihara T, Tsuyuguchi T, Nakamoto S, Miyakawa K, Sugiyama H, Yasui S, Fujimoto T, Eto R, Miyazaki M, Yokosuka O.  Clinical evaluation of endosonography-guided biliary drainage for patients with the difficulty with placing of internal drainage.  Hepatogastroenterology. 2009 Nov-Dec;56(96):1596-9.
24. Tada M, Kanai F, Tanaka Y, Sanada M, Nannya Y, Tateishi K, Ohta M, Asaoka Y, Seto M, Imazeki F, Yoshida H, Ogawa S, Yokosuka O, Omata M.  Prognostic significance of genetic alterations detected by high-density single nucleotide polymorphism array in gastric cancer.  Cancer Sci. 2010 May;101(5):1261-9. Epub 2010 Jan 19.
25. Sudo K, Yamaguchi T, Nakamura K, Denda T, Hara T, Ishihara T, Yokosuka O. Phase II study of S-1 in patients with gemcitabine-resistant advanced pancreatic cancer.  Cancer Chemother Pharmacol. 2011 Feb;67(2):249-54. Epub 2010 Mar 30.
26. Mimura N, Kojima H, Tsujimura H, Ise M, Sakai C, Fukai K, Yokosuka O, Kumagai K. [Prevention of hepatitis B virus reactivation in B-cell lymphoma patients receiving chemotherapy with rituximab].  Rinsho Ketsueki. 2010 Mar;51(3):213-5. Japanese.
27. Aoki R, Chiba T, Miyagi S, Negishi M, Konuma T, Taniguchi H, Ogawa M, Yokosuka O, Iwama A. The polycomb group gene product Ezh2 regulates proliferation and differentiation of murine hepatic stem/progenitor cells. J Hepatol. 2010 Jun;52(6):854-63. Epub 2010 Mar 24.
28. Yokosuka O, Takaguchi K, Fujioka S, Shindo M, Chayama K, Kobashi H, Hayashi N, Sato C, Kiyosawa K, Tanikawa K, Ishikawa H, Masaki N, Seriu T, Omata M. Long-term use of entecavir in nucleoside-naïve Japanese patients with chronic hepatitis B infection.J Hepatol. 2010 Jun;52(6):791-9. Epub 2010 Mar 24.
29. Sugawara T, Oguro H, Negishi M, Morita Y, Ichikawa H, Iseki T, Yokosuka O, Nakauchi H, Iwama A. FET family proto-oncogene Fus contributes to self-renewal of hematopoietic stem cells. Exp Hematol. 2010 Aug;38(8):696-706. Epub 2010 Apr 20.
30. Imada H, Kato H, Yasuda S, Yamada S, Yanagi T, Hara R, Kishimoto R, Kandatsu S, Minohara S, Mizoe JE, Kamada T, Yokosuka O, Tsujii H. Compensatory enlargement of the liver after treatment of hepatocellular carcinoma with carbon ion radiotherapy - relation to prognosis and liver function. Radiother Oncol. 2010 Aug;96(2):236-42. Epub 2010 Apr 21.
31. Mikata R, Fukai K, Imazeki F, Arai M, Fujiwara K, Yonemitsu Y, Zhang K, Nabeya Y, Ochiai T, Yokosuka O. BCL2L10 is frequently silenced by promoter hypermethylation in gastric cancer. Oncol Rep. 2010 Jun;23(6):1701-8.
32. Fujimoto T, Tsuyuguchi T, Sakai Y, Sugiyama H, Miyakawa K, Eto R, Yasui S, Ishihara T, Yokosuka O. Long-term outcome of endoscopic papillotomy for choledocholithiasis with cholecystolithiasis. Dig Endosc. 2010 Apr;22(2):95-100.
33. Imazeki F, Yokosuka O, Omata M. Impact of IL-28B SNPs on control of hepatitis C virus infection: a genome-wide association study. Expert Rev Anti Infect Ther. 2010 May;8(5):497-9.
34. Kasuga A, Mizumoto H, Matsutani S, Kobayashi A, Endo T, Ando T, Yukisawa S, Maruyama H, Yokosuka O. Portal hemodynamics and clinical outcomes of patients with gastric varices after balloon-occluded retrograde transvenous obliteration.  J Hepatobiliary Pancreat Sci. 2010 Nov;17(6):898-903. Epub 2010 May 12.
35. Takano S, Sogawa K, Yoshitomi H, Shida T, Mogushi K, Kimura F, Shimizu H, Yoshidome H, Ohtsuka M, Kato A, Ishihara T, Tanaka H, Yokosuka O, Nomura F, Miyazaki M. Increased circulating cell signalling phosphoproteins in sera are useful for the detection of pancreatic cancer. Br J Cancer. 2010 Jul 13;103(2):223-31. Epub 2010 Jun 15.
36. Kanda T, Imazeki F, Nakamoto S, Okitsu K, Fujiwara K, Yokosuka O. Internal ribosomal entry-site activities of clinical isolate-derived hepatitis A virus and inhibitory effects of amantadine. Hepatol Res. 2010 Apr 1;40(4):415-23. Epub 2010 Mar 29.
37. Imada H, Kato H, Yasuda S, Yamada S, Yanagi T, Kishimoto R, Kandatsu S, Mizoe JE, Kamada T, Yokosuka O, Tsujii H. Comparison of efficacy and toxicity of short-course carbon ion radiotherapy for hepatocellular carcinoma depending on their proximity to the porta hepatis. Radiother Oncol. 2010 Aug;96(2):231-5. Epub 2010 Jun 25.
38. Maruyama H, Okugawa H, Ishibashi H, Takahashi M, Kobayashi S, Yoshizumi H, Yokosuka O. Carbon dioxide-based portography: an alternative to conventional imaging with the use of iodinated contrast medium. J Gastroenterol Hepatol. 2010 Jun;25(6):1111-6.
39. Sudo K, Yamaguchi T, Ishihara T, Nakamura K, Hara T, Denda T, Tawada K, Imagumbai T, Araki H, Sakai M, Hatano K, Kawakami H, Uno T, Ito H, Yokosuka O.Phase II study of oral S-1 and concurrent radiotherapy in patients with unresectable locally advanced pancreatic cancer.  Int J Radiat Oncol Biol Phys. 2011 May 1;80(1):119-25. Epub 2010 Jun 3.
40. Fujiwara K, Yasui S, Okitsu K, Yonemitsu Y, Oda S, Yokosuka O. The requirement for a sufficient period of corticosteroid treatment in combination with nucleoside analogue for severe acute exacerbation of chronic hepatitis B. J Gastroenterol. 2010 Dec;45(12):1255-62.. Epub 2010 Jul 9.
41. Hamano Y, Okude T, Shirai R, Sato I, Kimura R, Ogawa M, Ueda Y, Yokosuka O, Kalluri R, Ueda S. Lack of collagen XVIII/endostatin exacerbates immune-mediated glomerulonephritis. J Am Soc Nephrol. 2010 Sep;21(9):1445-55. Epub 2010 Jul 8.
42. Chiba T, Seki A, Aoki R, Ichikawa H, Negishi M, Miyagi S, Oguro H, Saraya A, Kamiya A, Nakauchi H, Yokosuka O, Iwama A. Bmi1 promotes hepatic stem cell expansion and tumorigenicity in both Ink4a/Arf-dependent and -independent manners in mice. Hepatology. 2010 Sep;52(3):1111-23.
43. Ishibashi H, Maruyama H, Takahashi M, Fujiwara K, Imazeki F, Yokosuka O. Assessment of hepatic fibrosis by analysis of the dynamic behaviour of microbubbles during contrast ultrasonography.  Liver Int. 2010 Oct;30(9):1355-63.
44. Yang L, Kiyohara T, Kanda T, Imazeki F, Fujiwara K, Gauss-Müller V, Ishii K, Wakita T, Yokosuka O. Inhibitory effects on HAV IRES-mediated translation and replication by a combination of amantadine and interferon-alpha. Virol J. 2010 Sep 3;7:212.
45. Yasui S, Fujiwara K, Yonemitsu Y, Oda S, Nakano M, Yokosuka O. Clinicopathological features of severe and fulminant forms of autoimmune hepatitis. J Gastroenterol. 2011 Mar;46(3):378-90. Epub 2010 Sep 7.
46. Wu S, Kanda T, Imazeki F, Arai M, Yonemitsu Y, Nakamoto S, Fujiwara K, Fukai K, Nomura F, Yokosuka O. Hepatitis B virus e antigen downregulates cytokine production in human hepatoma cell lines.  Viral Immunol. 2010 Oct;23(5):467-76.
47. Wu S, Fukai K, Imazeki F, Arai M, Kanda T, Yonemitsu Y, Yokosuka O.Initial virological response and viral mutation with adefovir dipivoxil added to ongoing Lamivudine therapy in Lamivudine-resistant chronic hepatitis B. Dig Dis Sci. 2011 Apr;56(4):1207-14. Epub 2010 Oct 7.
48. Wu S, Imazeki F, Kurbanov F, Fukai K, Arai M, Kanda T, Yonemitsu Y, Tanaka Y, Mizokami M, Yokosuka O.  Evolution of hepatitis B genotype C viral quasi-species during hepatitis B e antigen seroconversion. J Hepatol. 2011 Jan;54(1):19-25. Epub 2010 Aug 25.
49. Fujiwara K, Yokosuka O. [Serum anti-hepatitis A virus antibody and hepatitis A virus RNA]. Nihon Rinsho. 2010 Jun;68 Suppl 6:435-8. Japanese.
50. Sakai Y, Tsuyuguchi T, Ishihara T, Sugiyama H, Miyakawa K, Yasui S, Eto R, Fujimoto T, Ohtsuka M, Miyazaki M, Yokosuka O. Usefulness of peroral cholangioscopy in preoperative diagnosis of intraductal papillary neoplasm of the bile duct. Hepatogastroenterology. 2010 Jul-Aug;57(101):691-3.
51. Inoue M, Miyake Y, Odaka T, Sato T, Watanabe Y, Sakama A, Zenbutsu S, Yokosuk O. Objective evaluation of visibility in virtual chromoendoscopy for esophageal squamous carcinoma using a color difference formula. J Biomed Opt. 2010 Sep-Oct;15(5):056019.
52. Sogawa K, Kodera Y, Satoh M, Kawashima Y, Umemura H, Maruyama K, Takizawa H, Yokosuka O, Nomura F. Increased serum levels of pigment epithelium-derived factor by excessive alcohol consumption-detection and identification by a three-step serum proteome analysis.  Alcohol Clin Exp Res. 2011 Feb;35(2):211-7. Epub 2010 Nov 8.
53. Kanda T, Imazeki F, Yokosuka O. New antiviral therapies for chronic hepatitis C. Hepatol Int. 2010 Aug 19;4(3):548-61.
54. Yokosuka O, Kurosaki M, Imazeki F, Arase Y, Tanaka Y, Chayama K, Tanaka E, Kumada H, Izumi N, Mizokami M, Kudo M. Management of hepatitis B: Consensus of the Japan Society of Hepatology 2009.  Hepatol Res. 2011 Jan;41(1):1-21. Epub 2010 Nov 11.
55. Kanda T, Imazeki F, Yonemitsu Y, Mikami S, Takada N, Nishino T, Takashi M, Tsubota A, Kato K, Sugiura N, Tawada A, Wu S, Tanaka T, Nakamoto S, Mikata R, Tada M, Chiba T, Kurihara T, Arai M, Fujiwara K, Kanai F, Yokosuka O. Quantification of hepatitis C virus in patients treated with peginterferon-alfa 2a plus ribavirin treatment by COBAS TaqMan HCV test. J Viral Hepat. 2011 Jul;18(7):e292-7.  Epub 2010 Dec 3.
56. Tomizawa M, Tsuyuguchi T, Sakai Y, Sugiyama H, Miyakawa K, Ishihara T, Yokosuka O. [Case of intrahepatic cholangiocarcinoma drained through a fistula of the duodenal bulb]. Nihon Shokakibyo Gakkai Zasshi. 2010 Dec;107(12):1970-7. Japanese.
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2011年教室業績
1. Bekku D, Arai M, Imazeki F, Yonemitsu Y, Kanda T, Fujiwara K, Fukai K, Sato K, Itoga S, Nomura F, Yokosuka O.  Long-term follow-up of patients with hepatitis B e antigen negative chronic hepatitis B.  J Gastroenterol Hepatol. 2011 Jan;26(1):122-8.
2. Fujiwara K, Kojima H, Yasui S, Okitsu K, Yonemitsu Y, Omata M, Yokosuka O. Hepatitis A viral load in relation to severity of the infection.  J Med Virol. 2011 Feb;83(2):201-7
3. Tsuyuguchi T, Sakai Y, Sugiyama H, Ishihara T, Yokosuka O.  Long-term follow-up after peroral cholangioscopy-directed lithotripsy in patients with difficult bile duct stones, including Mirizzi syndrome: an analysis of risk factors predicting stone recurrence. Surg Endosc. 2011 Jul;25(7):2179-85.. Epub 2010 Dec 24.
4. Matsumura T, Arai M, Sazuka S, Saito M, Takahashi Y, Maruoka D, Suzuki T, Nakagawa T, Sato T, Katsuno T, Imazeki F, Yokosuka O. Negative capsule endoscopy for obscure gastrointestinal bleeding is closely associated with the use of low-dose aspirin. Scand J Gastroenterol. 2011 May;46(5):621-6. Epub 2010 Dec 29.
5. Hamano Y, Okude T, Yokosuka O, Ogawa M. Attenuation of Immune-Mediated Renal Injury by Telmisartan, an Angiotensin Receptor Blocker and a Selective PPAR-γ Activator.Nephron Extra. 2011 Jan;1(1):78-90. Epub 2011 Sep 22.
6. Kanda T, Jeong SH, Imazeki F, Fujiwara K, Yokosuka O. Analysis of 5' nontranslated region of hepatitis A viral RNA genotype I from South Korea: comparison with disease severities. PLoS One. 2010 Dec 28;5(12):e15139.
7. Maruyama H, Takahashi M, Ishibashi H, Yoshikawa M, Yokosuka O.  Contrast-enhanced ultrasound for characterisation of hepatic lesions appearing non-hypervascular on CT in chronic liver diseases. Br J Radiol. 2012 Apr;85(1012):351-7. Epub 2011 Jan 11.
8. Arai M, Matsumura T, Yoshikawa M, Imazeki F, Yokosuka O. [Analysis of the Rikkunshito efficacy on patients with functional dyspepsia]. Nihon Yakurigaku Zasshi. 2011 Jan;137(1):18-21. Japanese.
9. Takahashi M, Maruyama H, Ishibashi H, Yoshikawa M, Yokosuka O. Contrast-enhanced ultrasound with perflubutane microbubble agent: evaluation of differentiation of hepatocellular carcinoma. AJR Am J Roentgenol. 2011 Feb;196(2):W123-31.
10. Fujiwara K, Yasui S, Tawada A, Okitsu K, Yonemitsu Y, Chiba T, Arai M, Kanda T, Imazeki F, Nakano M, Oda S, Yokosuka O. Autoimmune fulminant liver failure in adults: Experience in a Japanese center. Hepatol Res. 2011 Feb;41(2):133-41. 1
11. Furukawa K, Sato T, Katsuno T, Nakagawa T, Noguchi Y, Tokumasa A, Yokote K, Yokosuka O, Saito Y. Smad3 contributes to positioning of proliferating cells in colonic crypts by inducing EphB receptor protein expression. Biochem Biophys Res Commun. 2011 Feb 25;405(4):521-6. Epub 2011 Jan 26.
12. Maruyama H, Okugawa H, Kobayashi S, Yoshizumi H, Takahashi M, Ishibashi H, Yokosuka O. Non-invasive portography: a microbubble-induced three-dimensional sonogram for discriminating idiopathic portal hypertension from cirrhosis.  Br J Radiol. 2012 May;85(1013):587-95. Epub 2011 Feb 22.
13. Sogawa K, Kodera Y, Noda K, Ishizuka Y, Yamada M, Umemura H, Maruyama K, Tomonaga T, Yokosuka O, Nomura F. The measurement of a fibrinogen α C-chain 5.9 kDa fragment (FIC 5.9) using MALDI-TOF MS and a stable isotope-labeled peptide standard dilution.  Clin Chim Acta. 2011 May 12;412(11-12):1094-9. Epub 2011 Feb 24.
14. Nishimura M, Yamamoto H, Yoshida T, Seimiya M, Sawabe Y, Matsushita K, Umemura H, Sogawa K, Takizawa H, Yokosuka O, Nomura F. Decreases in the serum VLDL-TG/non-VLDL-TG ratio from early stages of chronic hepatitis C: alterations in TG-rich lipoprotein levels.  PLoS One. 2011 Feb 25;6(2):e17309.
15. Ambiru S, Nakamura S, Mandai Y, Sato T, Kuwahara T, Yokosuka O. Ectopic ileal varices associated with recurrent bleeding: report of a case. Surg Today. 2011 Mar;41(3):448-52. Epub 2011 Mar 2.
16. Fujiwara K, Nakano M, Yasui S, Okitsu K, Yonemitsu Y, Yokosuka O. Advancedhistology and impaired liver regeneration are associated with disease severity in acute-onset autoimmune hepatitis. Histopathology. 2011 Apr;58(5):693-704. Epub 2011 Mar 14.
17. Yasui S, Fujiwara K, Yokosuka O. Autoimmune fulminant hepatic failure in chronic hepatitis C during Peg-interferon-alpha 2b plus ribavirin treatment showing histological heterogeneity. ig Liver Dis. 2011 Aug;43(8):666-7. Epub 2011 Mar 24.
18. Fujiwara K, Yasui S, Yokosuka O. Efforts at making the diagnosis of acute-onset autoimmune hepatitis. Hepatology. 2011 Jul;54(1):371-2; author reply 373.
19. Ogasawara S, Kanai F, Obi S, Sato S, Yamaguchi T, Azemoto R, Mizumoto H, Koushima Y, Morimoto N, Hirata N, Toriyabe T, Shinozaki Y, Ooka Y, Mikata R, Chiba T, Okabe S, Imazeki F, Yoshikawa M, Yokosuka O.  Safety and tolerance of sorafenib in Japanese patients with advanced hepatocellular carcinoma. Hepatol Int. 2011 Sep;5(3):850-6. Epub 2011 Jan 22.
20. Watanabe S, Kishimoto T, Yokosuka O. Hepatocyte growth factor inhibits anoikis of pancreatic carcinoma cells through phosphatidylinositol 3-kinase pathway. Pancreas. 2011 May;40(4):608-14.
21. Nakamoto S, Kanda T, Imazeki F, Wu S, Arai M, Fujiwara K, Yokosuka O. Simple assay based on restriction fragment length polymorphism associated with IL28B in chronic hepatitis C patients. Scand J Gastroenterol. 2011 Jul;46(7-8):955-61.
22. Kanda T, Imazeki F, Azemoto R, Yonemitsu Y, Mikami S, Kita K, Takashi M, Sunaga M, Wu S, Nakamoto S, Tawada A, Arai M, Kato K, Yoshida Y, Koma Y, Fujiwara K, Fukai K, Suzuki N, Yokosuka O. Response to peginterferon-alfa 2b and ribavirin in Japanese patients with chronic hepatitis C genotype 2. Dig Dis Sci. 2011 Nov;56(11):3
23. Kamezaki H, Kanda T, Wu S, Nakamoto S, Arai M, Maruyama H, Fujiwara K, Imazeki F, Yokosuka O. Emergence of entecavir-resistant mutations in nucleos(t)ide-naive Japanese patients infected with hepatitis B virus: virological breakthrough is also dependent on adherence to medication. Scand J Gastroenterol. 2011 Sep;46(9):1111-7. Epub 2011 May 30.
24. Matsuyama M, Kondo F, Ishihara T, Yamaguchi T, Ito R, Tsuyuguchi T, Tawada K, Yokosuka O. Evaluation of pancreatic intraepithelial neoplasia and mucin expression in normal pancreata. J Hepatobiliary Pancreat Sci. 2012 May;19(3):242-8.
25. Okamoto Y, Masaki T, Murayama A, Munakata T, Nomoto A, Nakamoto S, Yokosuka O, Watanabe H, Wakita T, Kato T. Development of recombinant hepatitis C virus with NS5A from strains of genotypes 1 and 2. Biochem Biophys Res Commun. 2011 Jul 8;410(3):404-9. Epub 2011 Jun 6.
26. Takahashi D, Hase K, Kimura S, Nakatsu F, Ohmae M, Mandai Y, Sato T, Date Y, Ebisawa M, Kato T, Obata Y, Fukuda S, Kawamura YI, Dohi T, Katsuno T, Yokosuka O, Waguri S, Ohno H.  The epithelia-specific membrane trafficking factor AP-1B controls gut immune homeostasis in mice. Gastroenterology. 2011 Aug;141(2):621-32. . Epub 2011 May 5.
27. Yasui S, Fujiwara K, Tawada A, Fukuda Y, Nakano M, Yokosuka O.  fficacy of intravenous glycyrrhizin in the early stage of acute onset autoimmune hepatitis. Dig Dis Sci. 2011 Dec;56(12):3638-47. Epub 2011 Jun 17.
28. Maruyama H, Shimada T, Ishibashi H, Takahashi M, Kamesaki H, Yokosuka O. Delayed periportal enhancement: a characteristic finding on contrast ultrasound in idiopathic portal hypertension.  Hepatol Int. 2011 Jun 28. [Epub ahead of print]
29. Ueno H, Okusaka T, Furuse J, Yamao K, Funakoshi A, Boku N, Ohkawa S, Yokosuka O, Tanaka K, Moriyasu F, Nakamori S, Sato T. Multicenter phase II study of gemcitabine and S-1 combination therapy (GS Therapy) in patients with metastatic pancreatic cancer.  Jpn J Clin Oncol. 2011 Aug;41(8):953-8. Epub 2011 Jun 29.
30. Chiba T, Suzuki E, Negishi M, Saraya A, Miyagi S, Konuma T, Tanaka S, Tada M, Kanai F, Imazeki F, Iwama A, Yokosuka O. 3-Deazaneplanocin A is a promising therapeutic agent for the eradication of tumor-initiating hepatocellular carcinoma cells. Int J Cancer. 2012 Jun 1;130(11):2557-67. Epub 2011 Aug 20.
31. Kanda T, Imazeki F, Wu S, Nakamoto S, Yokosuka O. The assessment of serum hepatitis C virus RNA 12 weeks after the end of treatment using TaqMan polymerase chain reaction is less relevant than after 24 weeks for predicting sustained virological response. Hepatology. 2011 Oct;54(4):1482; author reply 1482-3. Epub 2011 Aug 11.
32. Fujiwara K, Yasui S, Tawada A, Fukuda Y, Nakano M, Yokosuka O. Diagnostic value and utility of the simplified International Autoimmune Hepatitis Group criteria in acute-onset autoimmune hepatitis. Liver Int. 2011 Aug;31(7):1013-20. Epub 2011 Apr 5.
33. Okitsu K, Kanda T, Imazeki F, Yonemitsu Y, Ray RB, Chang C, Yokosuka O. Genes Cancer. 2010 Aug;1(8):859-67.
34. Tanaka T, Arai M, Wu S, Kanda T, Miyauchi H, Imazeki F, Matsubara H, Yokosuka O. Epigenetic silencing of microRNA-373 plays an important role in regulating cell  liferation   in colon cancer. Oncol Rep. 2011 Nov;26(5):1329-35. Epub 2011 Jul 22.
35. Maruoka D, Imazeki F, Arai M, Kanda T, Fujiwara K, Yokosuka O. Long-term cohort study of chronic hepatitis C according to interferon efficacy.  J Gastroenterol Hepatol. 2012 Feb;27(2):291-9.
36. Kanda T, Imazeki F, Mikami S, Kato K, Shimada N, Yonemitsu Y, Miyauchi T, Arai M, Fujiwara K, Tsubota A, Takada N, Nishino T, Takashi M, Sugiura N, Kimura M, Fukai K, Yokosuka O.  Occurrence of hepatocellular carcinoma was not a rare event during and immediately after antiviral treatment in Japanese HCV-positive patients. Oncology. 2011;80(5-6):366-72. Epub 2011 Aug 3.
37. Sakai Y, Tsuyuguchi T, Mikata R, Tawada K, Tada M, Togo S, Tamura R, Saito M, Kurosawa J, Ishihara T, Yokosuka O. Utility of placement of pancreatic duct spontaneous dislodgement stent for prevention of post-ERCP pancreatitis in patients with difficulty in selective biliary cannulation.  Hepatogastroenterology. 2011 May-Jun;58(107-108):687-93.
38. Sakai Y, Tsuyuguchi T, Mikata R, Sugiyama H, Yasui S, Eto R, Fujimoto T, Tamura R, Togo S, Tada M, Ishihara T, Yokosuka O. Pancreatic duct guidewire-indwelling method for patients resistant to selective biliary cannulation and usefulness of pre-cut papillotomy following unsuccessful biliary cannulation with pancreatic duct guidewire-indwelling method.  Hepatogastroenterology. 2011 May-Jun;58(107-108):698-704.
39. Origasa H, Goto S, Shimada K, Uchiyama S, Okada Y, Sugano K, Hiraishi H, Uemura N, Ikeda Y; MAGIC Investigators. Prospective cohort study of gastrointestinal complications and vascular diseases in patients taking aspirin: rationale and design of the MAGIC Study. Cardiovasc Drugs Ther. 2011 Dec;25(6):551-60.
40. Tamura R, Kanda T, Imazeki F, Wu S, Nakamoto S, Tanaka T, Arai M, Fujiwara K, Saito K, Roger T, Wakita T, Shirasawa H, Yokosuka O. Hepatitis C Virus nonstructural 5A protein inhibits lipopolysaccharide-mediated apoptosis of hepatocytes by decreasing expression of Toll-like receptor 4. J Infect Dis. 2011 Sep 1;204(5):793-801.
41. Etoh R, Imazeki F, Kurihara T, Fukai K, Fujiwara K, Arai M, Kanda T, Mikata R, Yonemitsu Y, Yokosuka O. Pegylated interferon-alfa-2a monotherapy in patients infected with HCV genotype 2 and importance of rapid virological response. BMC Res Notes. 2011 Aug 31;4:316.
42. Wu S, Kanda T, Imazeki F, Nakamoto S, Shirasawa H, Yokosuka O. Nuclear receptor mRNA expression by HBV in human hepatoblastoma cell lines. Cancer Lett. 2011 Dec 15;312(1):33-42. Epub 2011 Aug 22.
43. Maruyama H, Ishibashi H, Takahashi M, Shimada T, Kamesaki H, Yokosuka O. Prediction of the therapeutic effects of anticoagulation for recent portal vein thrombosis: a novel approach with contrast-enhanced ultrasound. Abdom Imaging. 2012 Jun;37(3):431-8.
44. Togo S, Arai M, Tawada A, Chiba T, Kanda T, Fujiwara K, Imazeki F, Yokosuka O. Clinical importance of serum hepatitis B surface antigen levels in chronic hepatitis B. J Viral Hepat. 2011 Oct;18(10):e508-15. Epub 2011 Jul 22.
45. Yasui S, Fujiwara K, Okitsu K, Yonemitsu Y, Ito H, Yokosuka O. Importance of computed tomography imaging features for the diagnosis of autoimmune acute liver failure. Hepatol Res. 2012 Jan;42(1):42-50. Epub 2011 Oct 11.
46. Suzuki T, Arai M, Matsumura T, Arai E, Hata S, Maruoka D, Tanaka T, Nakamoto S, Imazeki F, Yokosuka O. Factors Associated with Inadequate Tissue Yield in EUS-FNA for Gastric SMT. ISRN Gastroenterol. 2011;2011:619128. Epub 2011 Jun 1.
47. Sakai Y, Tsuyuguchi T, Sugiyama H, Kurosawa J, Saito M, Tawada K, Mikata R, Tada M, Ishihara T, Yokosuka O. Transpancreatic precut papillotomy in patients with difficulty in selective biliary cannulation. Hepatogastroenterology. 2011 Nov-Dec;58(112):1853-8.
48. Narahara Y, Kanazawa H, Sakamoto C, Maruyama H, Yokosuka O, Mochida S, Uemura M, Fukui H, Sumino Y, Matsuzaki Y, Masaki N, Kokubu S, Okita K. The efficacy and safety of terlipressin and albumin in patients with type 1 hepatorenal syndrome: a multicenter, open-label, explorative study. J Gastroenterol. 2012 Mar;47(3):313-20. Epub 2011 Oct 25.
49. Fujiwara K, Yokosuka O. Histological discrimination between autoimmune hepatitis and drug-induced liver injury. Hepatology. 2012 Feb;55(2):657.
50. Imazeki F, Wu S, Arai M, Kanda T, Yokosuka O. [HBeAg and HBV DNA in chronic hepatitis B]. Nihon Rinsho. 2011 May;69 Suppl 4:428-33. Japanese.
51. Yokosuka O, Arai M. [The factors associated with pathology, treatment and prognosis of chronic hepatitis B]. Nihon Rinsho. 2011 May;69 Suppl 4:462-8. Japanese. No abstract available.
52. Matsumoto A, Tanaka E, Suzuki Y, Kobayashi M, Tanaka Y, Shinkai N, Hige S, Yatsuhashi H, Nagaoka S, Chayama K, Tsuge M, Yokosuka O, Imazeki F, Nishiguchi S, Saito M, Fujiwara K, Torii N, Hiramatsu N, Karino Y, Kumada H. Combination of hepatitis B viral antigens and DNA for prediction of relapse after discontinuation of nucleos(t)ide analogs in patients with chronic hepatitis B. Hepatol Res. 2012 Feb;42(2):139-149. Epub 2011 N ov 22.
53. Sakai Y, Ishihara T, Tsuyuguchi T, Tawada K, Saito M, Kurosawa J, Tamura R, Togo S, Mikata R, Tada M, Yokosuka O. New cannulation method for pancreatic duct cannulation-bile duct guidewire-indwelling method. World J Gastrointest Endosc. 2011 Nov 16;3(11):231-4.
54. Miyamura T, Ishii K, Kanda T, Tawada A, Sekimoto T, Wu S, Nakamoto S, Arai M,    Fujiwara K, Imazeki F, Kiyohara T, Wakita T, Yokosuka O. Possible widespread presence of hepatitis A virus subgenotype IIIA in Japan: Recent trend of hepatitis A causing acute liver failure. Hepatol Res. 2012 Mar;42(3):248-53. Epub 2011 Dec 13.
55. Murayama A, Kato T, Akazawa D, Sugiyama N, Date T, Masaki T, Nakamoto S, Tanaka Y, Mizokami M, Yokosuka O, Nomoto A, Wakita T. Production of infectious chimeric hepatitis C virus genotype 2b harboring minimal regions of JFH-1. J Virol. 2012 Feb;86(4):2143-52.  Epub 2011 Dec 7.
56. Miyamura T, Kanda T, Nakamoto S, Wu S, Fujiwara K, Imazeki F, Yokosuka O. Hepatic  STAT1-nuclear translocation and interleukin 28B polymorphisms predict treatment outcomes in hepatitis C virus genotype 1-infected patients. PLoS One. 2011;6(12):e28617. Epub 2011 Dec 12.
57. Ishibashi H, Maruyama H, Takahashi M, Shimada T, Kamesaki H, Fujiwara K, Imazeki F, Yokosuka O. Demonstration of intrahepatic accumulated microbubble on ultrasound represents the grade of hepatic fibrosis. Eur Radiol. 2012 May;22(5):1083-90. Epub 2011 Dec 30.
58. Kanda T, Shinozaki M, Kamezaki H, Wu S, Nakamoto S, Arai M, Fujiwara K, Goto N, Imazeki F, Yokosuka O. Efficacy of lamivudine or entecavir on acute exacerbation of chronic hepatitis B. Int J Med Sci. 2012;9(1):27-32. Epub 2011 Nov 10.
59. Seza K, Yamaguchi T, Ishihara T, Tadenema H, Tawada K, Saisho H, Yokosuka O. A long-term controlled trial of endoscopic pancreatic stenting for treatment of main pancreatic duct stricture in chronic pancreatitis. Hepatogastroenterology. 2011 Nov-Dec;58(112):2128-31.
60. Maruoka D, Imazeki F, Arai M, Kanda T, Fujiwara K, Yokosuka O. Longitudinal changes of the laboratory data of chronic hepatitis C patients with sustained virological response on long-term follow-up. J Viral Hepat. 2012 Feb;19(2):e97-104. Epub 2011 Oct 4.
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2012年教室業績
1. Arai M, Matsumura T, Tsuchiya N, Sadakane C, Inami R, Suzuki T, Yoshikawa M, Imazeki F, Yokosuka O. Rikkunshito improves the symptoms in patients with functional dyspepsia, accompanied by an increase in the level of plasma ghrelin. Hepatogastroenterology. 2012 Jan-Feb;59(113):62-6.
2. Maruyama H, Takahashi M, Sekimoto T, Kamesaki H, Shimada T, Kanai F, Yokosuka O. Heterogeneity of microbubble accumulation: a novel approach to discriminate between well-differentiated hepatocellular carcinomas and regenerative nodules. Ultrasound Med Biol. 2012 Mar;38(3):383-8. Epub 2012 Jan 20.
3. Fujiwara K, Yokosuka O. Frequent detection of immunoglobulin M anti-herpes simplex viral antibody in patients with primary biliary cirrhosis. Hepatology. 2012 Jul;56(1):395.
4. Arai M, Togo S, Kanda T, Fujiwara K, Imazeki F, Yokosuka O. Quantification of hepatitis B surface antigen can help predict spontaneous hepatitis B surface antigen seroclearance. Eur J Gastroenterol Hepatol. 2012 Apr;24(4):414-8.
5. Tanaka T, Sugaya S, Kita K, Arai M, Kanda T, Fujii K, Imazeki F, Sugita K, Yokosuka O, Suzuki N. Inhibition of cell viability by human IFN-β is mediated by microRNA-431. Int J Oncol. 2012 May;40(5):1470-6. Epub 2012 Jan 24.
6. Kanda T, Yokosuka O. Pegylated interferon-alfa plus ribavirin therapies for chronic hepatitis C. JNMA J Nepal Med Assoc. 2011 Jan-Mar;51(181):41-8.
7. Sakai Y, Tsuyuguchi T, Sugiyama H, Nishikawa T, Tawada K, Saito M, Kurosawa J, Mikata R, Tada M, Ishihara T, Yokosuka O. Current situation of endoscopic treatment for common bile duct stones. Hepatogastroenterology. 2012 Sep;59(118):1712-6.
8. Sazuka S, Takahashi Y, Kawaguchi T, Sato T, Nakagawa T, Furuya Y, Saito M, Saito K, Katsuno T, Nakaseko C, Yokosuka O. Endoscopic findings of small-intestinal Epstein-Barr virus-associated T-cell lymphoproliferative disorder. Endoscopy. 2012;44 Suppl 2 UCTN:E30-1. Epub 2012 Mar 6.
9. Saito M, Katsuno T, Nakagawa T, Sato T, Noguchi Y, Sazuka S, Saito K, Arai M, Yokote K, Yokosuka O. Intestinal epithelial cells with impaired autophagy lose their adhesive capacity in the presence of TNF-α. Dig Dis Sci. 2012 Aug;57(8):2022-30. Epub 2012 Mar 31.
10. Maruyama H, Takahashi M, Shimada T, Yokosuka O. Emergency anticoagulation treatment for cirrhosis patients with portal vein thrombosis and acute variceal bleeding. Scand J Gastroenterol. 2012 Jun;47(6):686-91. Epub 2012 Apr 4.
11. Maruyama K, Yokoyama A, Matsui T, Mizukami T, Mizukami Y, Sogawa K, Yokosuka O,  Nomura F, Yokoyama T. Higher serum free glycerol levels in a group of alcoholics than in controls. Alcohol Clin Exp Res. 2012 Oct;36(10):1820-6.. Epub 2012 Apr 6.
12. Arai E, Arai M, Uchiyama T, Higuchi Y, Aoyagi K, Yamanaka Y, Yamamoto T, Nagano O, Shiina A, Maruoka D, Matsumura T, Nakagawa T, Katsuno T, Imazeki F, Saeki N, Kuwabara S, Yokosuka O. Subthalamic deep brain stimulation can improve gastric emptying in Parkinson's disease. Brain. 2012 May;135(Pt 5):1478-85. Epub 2012 Apr 19.
13. Yan J, Kanda T, Wu S, Imazeki F, Yokosuka O. Hepatitis A, B, C and E virus markers in Chinese residing in Tokyo, Japan. Hepatol Res. 2012 Oct;42(10):974-81. Epub 2012 Apr 23.
14. Nomura F, Sogawa K, Noda K, Seimiya M, Matsushita K, Miura T, Tomonaga T, Yoshitomi H, Imazeki F, Takizawa H, Mogushi K, Miyazaki M, Yokosuka O. Serum anti-Ku86 is a potential biomarker for early detection of hepatitis C virus-related hepatocellular carcinoma. Biochem Biophys Res Commun. 2012 May 18;421(4):837-43. Epub 2012 Apr 25.
15. Kaneko S, Furuse J, Kudo M, Ikeda K, Honda M, Nakamoto Y, Onchi M, Shiota G, Yokosuka O, Sakaida I, Takehara T, Ueno Y, Hiroishi K, Nishiguchi S, Moriwaki H, Yamamoto K, Sata M, Obi S, Miyayama S, Imai Y. Guideline on the use of new anticancer drugs for the treatment of Hepatocellular Carcinoma 2010 update. Hepatol Res. 2012 Jun;42(6):523-542.
16. Ashinuma H, Takiguchi Y, Kitazono S, Kitazono-Saitoh M, Kitamura A, Chiba T, Tada Y, Kurosu K, Sakaida E, Sekine I, Tanabe N, Iwama A, Yokosuka O, Tatsumi K. Antiproliferative action of metformin in human lung cancer cell lines. Oncol Rep. 2012 Jul;28(1):8-14. Epub 2012 Apr 18.
17. Suzuki E, Chiba T, Zen Y, Miyagi S, Tada M, Kanai F, Imazeki F, Miyazaki M, Iwama A, Yokosuka O. Aldehyde dehydrogenase 1 is associated with recurrence-free survival but not stem cell-like properties in hepatocellular carcinoma. Hepatol Res. 2012 Nov;42(11):1100-11. Epub 2012 May 14.
18. Wu S, Kanda T, Imazeki F, Nakamoto S, Tanaka T, Arai M, Roger T, Shirasawa H, Nomura F, Yokosuka O. Hepatitis B virus e antigen physically associates with receptor-interacting serine/threonine protein kinase 2 and regulates IL-6 gene expression. J Infect Dis. 2012 Aug 1;206(3):415-20. Epub 2012 May 21.
19. Hata S, Arai M, Suzuki T, Maruoka D, Matsumura T, Nakagawa T, Katsuno T, Imazeki F, Yokosuka O. Clinical significance of endoscopic ultrasound for gastric submucosal tumors. Clin Res Hepatol Gastroenterol. 2013 Apr;37(2):207-12. Epub 2012 May 23.
20. Sakai Y, Tsuyuguchi T, Sugiyama H, Nishikawa T, Kurosawa J, Saito M, Tawada K, Mikata R, Tada M, Ishihara T, Yokosuka O. Endoscopic Sphincterotomy Combined with Large Balloon Dilation for Removal of Large Bile Duct Stones. Hepatogastroenterology. 2012 May 29;60(121). [Epub ahead of print]
21. Maruyama H, Yokosuka O. Pathophysiology of portal hypertension and esophageal varices. Int J Hepatol. 2012;2012:895787. Epub 2012 May 15.
22. 13.  Shimada T, Maruyama H, Sekimoto T, Kamezaki H, Takahashi M, Yokosuka O. Heterogeneous staining in the liver parenchyma after the injection of perflubutane microbubble contrast agent. Ultrasound Med Biol. 2012 Aug;38(8):1317-23. Epub 2012 Jun 12.
23. Kanaya T, Hase K, Takahashi D, Fukuda S, Hoshino K, Sasaki I, Hemmi H, Knoop KA, Kumar N, Sato M, Katsuno T, Yokosuka O, Toyooka K, Nakai K, Sakamoto A, Kitahara Y, Jinnohara T, McSorley SJ, Kaisho T, Williams IR, Ohno H. The Ets transcription factor Spi-B is essential for the differentiation of intestinal microfold cells. Nat Immunol. 2012 Jun 17;13(8):729-36.
24. Tominaga A, Kanda T, Akiike T, Komoda H, Ito K, Abe A, Aruga A, Kaneda S, Saito M, Kiyohara T, Wakita T, Ishii K, Yokosuka O, Sugiura N. Hepatitis A outbreak associated with a revolving sushi bar in Chiba, Japan: Application of molecular epidemiology. Hepatol Res. 2012 Aug;42(8):828-34.
25. Seimiya M, Ohno S, Yamamoto H, Fujiwara K, Yoshida T, Sawabe Y, Sogawa K, Matsushita K, Yokosuka O, Nomura F. Child-Pugh score is altered by the albumin measurement method. Hepatology. 2013 May;57(5):2093-4. Epub 2012 Sep 24.
26. Tsuyuguchi T, Sugiyama H, Sakai Y, Nishikawa T, Yokosuka O, Mayumi T, Kiriyama S, Yokoe M, Takada T. Prognostic factors of acute cholangitis in cases managed using the Tokyo Guidelines.J Hepatobiliary Pancreat Sci. 2012 Sep;19(5):557-65.
27. Izumi N, Asahina Y, Kurosaki M, Yamada G, Kawai T, Kajiwara E, Okamura Y,  Takeuchi T, Yokosuka O, Kariyama K, Toyoda J, Inao M, Tanaka E, Moriwaki H, Adachi H, Katsushima S, Kudo M, Takaguchi K, Hiasa Y, Chayama K, Yatsuhashi H, Oketani M, Kumada H. Inhibition of hepatocellular carcinoma by PegIFNα-2a in patients with chronic hepatitis C: a nationwide multicenter cooperative study. J Gastroenterol. 2013 Mar;48(3):382-90. Epub 2012 Aug 9.
28. Kikkawa S, Sogawa K, Satoh M, Umemura H, Kodera Y, Matsushita K, Tomonaga T, Miyazaki M, Yokosuka O, Nomura F. Identification of a Novel Biomarker for Biliary Tract Cancer Using Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry. Int J Proteomics. 2012;2012:108609. Epub 2012 Jul 25.
29. Sato T, Miyawaki T, Katsuno T, Nakagawa T, Inoue M, Watanabe Y, Hishikawa E, Arai M, Yokosuka O. Flicking method: a novel colonoscope insertion method for surveillance colonoscopy in ulcerative colitis patients. Dig Endosc. 2012 Sep;24(5):343-7. Epub 2012 Mar 15.
30. Wakamatsu T, Kanda T, Tawada A, Miyamura T, Takahashi M, Chiba T, Arai M, Maruyama H, Fujiwara K, Imazeki F, Yokosuka O. Acute liver failure in an antimitochondrial antibody-positive 63-year-old man. Case Rep Gastroenterol. 2012 May;6(2):394-9. Epub 2012 Jun 19.
31. Kimura A, Sogawa K, Satoh M, Kodera Y, Yokosuka O, Tomonaga T, Nomura F. The application of a three-step serum proteome analysis for the discovery and identification of novel biomarkers of hepatocellular carcinoma. Int J Proteomics. 2012;2012:623190. Epub 2012 Aug 16.
32. Saito K, Katsuno T, Nakagawa T, Saito M, Sazuka S, Sato T, Matsumura T, Arai M, Miyauchi H, Matsubara H, Yokosuka O. Predictive factors of response to intravenous ciclosporin in severe ulcerative colitis: the development of a novel prediction formula. Aliment Pharmacol Ther. 2012 Oct;36(8):744-54. Epub 2012 Sep 7.
33. Hata S, Arai M, Maruoka D, Tanaka T, Matsumura T, Suzuki T, Nakagawa T, Katsuno T, Imazeki F, Yokosuka O. Intragastric acidity during the first day following administration of low-dose proton pump inhibitors: A randomized crossover study. Clin Res Hepatol Gastroenterol. 2012 Sep 5. [Epub ahead of print]
34. Sugiyama H, Tsuyuguchi T, Sakai Y, Nisikawa T, Miyazaki M, Yokosuka O. Preoperative Drainage for Distal Biliary Obstruction: Endoscopic Stenting or Nasobiliary Drainage? Hepatogastroenterology. 2012 Sep 14;60(122). [Epub ahead of print]
35. Wu S, Kanda T, Nakamoto S, Imazeki F, Yokosuka O. Knockdown of receptor-interacting serine/threonine protein kinase-2 (RIPK2) affects EMT-associated gene expression in human hepatoma cells. Anticancer Res. 2012 Sep;32(9):3775-83.
36. Sazuka S, Katsuno T, Nakagawa T, Saito M, Saito K, Matsumura T, Arai M, Sato T, Yokosuka O. Concomitant use of enteral nutrition therapy is associated with sustained response to infliximab in patients with Crohn's disease. Eur J Clin Nutr. 2012 Nov;66(11):1219-23. Epub 2012 Sep 26.
37. Miyamura T, Kanda T, Nakamoto S, Wu S, Jiang X, Arai M, Fujiwara K, Imazeki F, Yokosuka O. Roles of ITPA and IL28B genotypes in chronic hepatitis C patients treated with peginterferon plus ribavirin. Viruses. 2012 Aug;4(8):1264-78. Epub 2012 Aug 14.
38. Oonishi K, Cui X, Hirakawa H, Fujimori A, Kamijo T, Yamada S, Yokosuka O, Kamada T. Different effects of carbon ion beams and X-rays on clonogenic survival and DNA repair in human pancreatic cancer stem-like cells. Radiother Oncol. 2012 Nov;105(2):258-65. Epub 2012 Sep 24.
39. Takahashi M, Maruyama H, Shimada T, Kamezaki H, Okabe S, Kanai F, Yoshikawa M, Yokosuka O. Linear enhancement after radio-frequency ablation for hepatocellular carcinoma: is it a sign of recurrence? Ultrasound Med Biol. 2012 Nov;38(11):1902-10.
40. Kanda T, Wu S, Kiyohara T, Nakamoto S, Jiang X, Miyamura T, Imazeki F, Ishii K, Wakita T, Yokosuka O. Interleukin-29 suppresses hepatitis A and C viral internal ribosomal entry site-mediated translation. Viral Immunol. 2012 Oct;25(5):379-86.
41. Mikata R, Ishihara T, Tada M, Tawada K, Saito M, Kurosawa J, Sugiyama H, Sakai Y,  Tsuyuguchi T, Miyazaki M, Yokosuka O. Clinical usefulness of repeated pancreatic juice cytology via endoscopic naso-pancreatic drainage tube in patients with pancreatic cancer. J Gastroenterol. 2012 Oct 10. [Epub ahead of print]
42. Sakai Y, Tsuyuguchi T, Kato K, Sugiyama H, Nishikawa T, Takahashi M, Yokosuka O. Clinical usefulness of doripenem (DRPM), a carbapenem antimicrobial drug, for the treatment of patients with acute cholangitis: retrospective study. Int J Clin Pharmacol Ther. 2013 Jan;51(1):19-25.
43. Yamamoto K, Miyake Y, Ohira H, Suzuki Y, Zeniya M, Onji M, Tsubouchi H; the Intractable Liver and Biliary Diseases Study Group of Japan. Prognosis of autoimmune hepatitis showing acute presentation. Hepatol Res. 2012 Sep 26. [Epub ahead of print]
44. Takahashi M, Maruyama H, Shimada T, Kamezaki H, Sekimoto T, Kanai F, Yokosuka O. Characterization of hepatic lesions (≤ 30 mm) with liver-specific contrast agents: a comparison between ultrasound and magnetic resonance imaging. Eur J Radiol. 2013 Jan;82(1):75-84.Epub 2012 Oct 29.
45. Inoue M, Chiba T, Zen Y, Yokota H, Kanda T, Ogasawara S, Sugiyama H, Arai M, Kanai F, Ogawa M, Imazeki F, Yokosuka O. Hepatic sarcoidosis with an increased serum level of immunoglobulin G4. Intern Med. 2012;51(21):3095-8. Epub 2012 Nov 1.
46. Matsumura T, Arai M, Sato T, Nakagawa T, Maruoka D, Tsuboi M, Hata S, Arai E, Katsuno T, Imazeki F, Yokosuka O.  Efficacy of computed image modification of capsule endoscopy in patients with obscure gastrointestinal bleeding. World J Gastrointest Endosc. 2012 Sep 16;4(9):421-8.
47. Saito M, Ishihara T, Tada M, Tsuyuguchi T, Mikata R, Sakai Y, Tawada K, Sugiyama H, Kurosawa J, Otsuka M, Uchida Y, Uchiyama K, Miyazaki M, Yokosuka O. Use of F-18 fluorodeoxyglucose positron emission tomography with dual-phase imaging to identify intraductal papillary mucinous neoplasm.  Clin Gastroenterol Hepatol. 2013 Feb;11(2):181-6. Epub 2012 Nov 6.
48. Katsuno T, Saito K, Yokosuka O.  Letter: should colectomy be the end-point to evaluate the effectiveness of drug therapies in severe ulcerative colitis? Authors' reply. Aliment Pharmacol Ther. 2013 Jan;37(1):161.
49. Ooka Y, Kanai F, Okabe S, Ueda T, Shimofusa R, Ogasawara S, Chiba T, Sato Y, Yoshikawa M, Yokosuka O. Gadoxetic acid-enhanced MRI compared with CT during angiography in the diagnosis of hepatocellular carcinoma.  Magn Reson Imaging. 2013 Jun;31(5):748-54. Epub 2012 Dec 5.
50. Nishikawa T, Tsuyuguchi T, Sakai Y, Sugiyama H, Miyazaki M, Yokosuka O. Comparison of the diagnostic accuracy of peroral video-cholangioscopic visual findings and cholangioscopy-guided forceps biopsy findings for indeterminate biliary lesions: a prospective study. Gastrointest Endosc. 2013 Feb;77(2):219-26. Epub 2012 Dec 8.
51. Sugiyama H, Tsuyuguchi T, Sakai Y, Ohtsuka M, Miyazaki M, Yokosuka O. Potential role of peroral cholangioscopy for preoperative diagnosis of cholangiocarcinoma. Surg Laparosc Endosc Percutan Tech. 2012 Dec;22(6):532-6.
52. Abe K, Katsushima F, Kanno Y, Takahashi A, Yokokawa J, Ohira H, Arinaga T, Ide T, Nishimura J, Inoue M, Seike M, Imazeki F, Yokosuka O, Sata  M. Clinical features of cirrhosis in Japanese patients with type I autoimmune hepatitis. Intern Med. 2012;51(24):3323-8. Epub 2012 Dec 15.
53. Ueda T, Tsuchiya K, Hashimoto S, Inoue T, Enomoto N, Inao M, Tanaka A, Kaito M, Imazeki F, Nishiguchi S, Mochida S, Yokosuka O, Yatsuhashi H, Izumi N, Kudo M; RETRY Study Group Retreatment with peginterferon α-2a + ribavirin in patients who failed previous peginterferon α-2b + ribavirin combination therapy.  Dig Dis. 2012;30(6):554-60. Epub 2012 Dec 13.
54. Maruyama H, Yokosuka O. Contrast-enhanced Ultrasound for Non-tumor Liver  Diseases. JNMA J Nepal Med Assoc. 2012 Jan-Mar;52(185):43-8.
55. Suzuki Y, Ohtake T, Nishiguchi S, Hashimoto E, Aoyagi Y, Onji M, Kohgo Y; The Japan Non-B, Non-C Liver Cirrhosis Study Group. Survey of non-B, non-C liver cirrhosis in Japan. Hepatol Res. 2012 Dec 26. [Epub ahead of print]
このページの先頭に戻る
2013年教室業績
1. Chiba T, Kanai F, Iwama A, Yokosuka O. Circulating cancer stem cells: a novel prognostic predictor of hepatocellular carcinoma. Hepatobiliary Surg Nutr. 2013 Feb;2(1):4-6.
2. Hosokawa I, Shimizu H, Ohtsuka M, Kato A, Yoshitomi H, Furukawa K, TakayashikiT, Ishihara T, Yokosuka O, Miyazaki M. Preoperative diagnosis and surgical management for solid pseudopapillary neoplasm of the pancreas. J Hepatobiliary Pancreat Sci. 2014 Feb 17. [Epub ahead of print]
3. Wu S, Nakamoto S, Kanda T, Jiang X, Nakamura M, Miyamura T, Shirasawa H, Sugiura N, Takahashi-Nakaguchi A, Gonoi T, Yokosuka O. Ultra-deep sequencing analysis of the hepatitis A virus 5'-untranslated region among cases of the same outbreak from a single source. Int J Med Sci. 2013 Dec 20;11(1):60-4.
4. Wu S, Kanda T, Nakamoto S, Imazeki F, Yokosuka O. Hepatitis C virus protease inhibitor-resistance mutations: our experience and review. World J Gastroenterol. 2013 Dec 21;19(47):8940-8.
5. Kanogawa N, Kanda T, Ohtsuka M, Nakamura M, Miyamura T, Yasui S, Arai M, Maruyama H, Fujiwara K, Shozu M, Oda S, Miyazaki M, Yokosuka O. Acute Liver Failure Occurring during the First Trimester of Pregnancy Successfully Treated with Living Donor Liver Transplantation. Case Rep Transplant. 2013;2013:309545.
6. Maruyama H, Kamezaki H, Kondo T, Sekimoto T, Takahashi M, Yokosuka O. Sonographic and clinical features of collateral vessels at the splenic hilum in cirrhosis. Clin Radiol. 2014 Mar;69(3):e140-5.
7. Nakamura M, Kanda T, Nakamoto S, Miyamura T, Jiang X, Wu S, Yokosuka O. No correlation between PNPLA3 rs738409 genotype and fatty liver and hepatic cirrhosis in Japanese patients with HCV. PLoS One. 2013 Dec 11;8(12):e81312.
8. Sato A, Sata M, Ikeda K, Kumada T, Izumi N, Asahina Y, Osaki Y, Chayama K, Kaneko S, Sakai A, Onji M, Hiasa Y, Omura T, Ozeki I, Yokosuka O, Shiina S, Itsubo M, Nishiguchi S, Hirano K, Ide T, Sakisaka S, Yamasaki T, Hidaka I, Tanaka M, Kim SR, Ichida T. Clinical characteristics of patients who developed hepatocellular carcinoma after hepatitis C virus eradication with interferon therapy: current status in Japan. Intern Med. 2013;52(24):2701-6.
9. Okimoto K, Ogasawara S, Chiba T, Ooka Y, Oobu M, Azemoto R, Kanogawa N, Motoyama T, Suzuki E, Tawada A, Yoshikawa M, Yokosuka O. Efficacy of transcatheter arterial chemoembolization with miriplatin-lipiodol water-soluble contrast agent emulsion in patients with hepatocellular carcinoma. Anticancer Res. 2013 Dec;33(12):5603-9.
10. Sudo K, Ishihara T, Hirata N, Ozawa F, Ohshima T, Azemoto R, Shimura K, Nihei T, Nishino T, Nakagawa A, Nakamura K, Hara T, Tada M, Mikata R, Tawada K, Yokosuka O, Nakaji S, Yamaguchi T. Randomized controlled study of gemcitabine plus S-1 combination chemotherapy versus gemcitabine for unresectable pancreatic cancer. Cancer Chemother Pharmacol. 2014 Feb;73(2):389-96.
11. Miyamura T, Kanda T, Nakamura M, Jiang X, Wu S, Nakamoto S, Mikami S, Takada N, Imazeki F, Yokosuka O. IL-28B polymorphisms and treatment response in hepatitis C virus patients with persistently normal alanine aminotransferase. World J Hepatol. 2013 Nov 27;5(11):635-41.
12. Motoyama T, Ogasawara S, Chiba T, Suzuki E, Yokota H, Haga Y, Kanogawa N, Saito T, Ooka Y, Tawada A, Kanai F, Yokosuka O. Successful non-surgical treatment of ruptured pyogenic liver abscess. Intern Med. 2013;52(23):2619-22.
13. Kanda T, Yokosuka O, Omata M. Antiviral therapy for "difficult-to-treat" hepatitis C virus-infected patients. Chin Med J (Engl). 2013 Dec;126(23):4568-74.
14. Fujiwara K, Yasui S, Yokosuka O. Corticosteroid for severe acute exacerbation of chronic hepatitis B. Eur J Gastroenterol Hepatol. 2013 Dec;25(12):1492.
15. Kitazono S, Takiguchi Y, Ashinuma H, Saito-Kitazono M, Kitamura A, Chiba T, Sakaida E, Sekine I, Tada Y, Kurosu K, Sakao S, Tanabe N, Iwama A, Yokosuka O, Tatsumi K. Effect of metformin on residual cells after chemotherapy in a human lung adenocarcinoma cell line. Int J Oncol. 2013 Dec;43(6):1846-54.
16. Fujiwara K, Yasui S, Yokosuka O. Letter: treatment of autoimmune acute liver failure--beyond consensus guidelines. Aliment Pharmacol Ther. 2013 Nov;38(9):1143-4.
17. Sakai Y, Tsuyuguchi T, Hirata N, Sugiyama H, Shimura K, Nakaji S, Shiratori T, Fujimoto T, Tsuchiya S, Mikami S, Yokosuka O. Long term outcome of the WallFlex partially covered stent for unresectable malignant biliary obstruction: a multicenter single-arm prospective study. Hepatogastroenterology. 2013 Oct 2;60(128).
18. Wu S, Kanda T, Nakamoto S, Jiang X, Miyamura T, Nakatani SM, Ono SK, Takahashi-Nakaguchi A, Gonoi T, Yokosuka O. Prevalence of hepatitis C virus subgenotypes 1a and 1b in Japanese patients: ultra-deep sequencing analysis of HCV NS5B genotype-specific region. PLoS One. 2013 Sep 17;8(9):e73615.
19. Tawada K, Ishihara T, Yamaguchi T, Tsuyuguchi T, Hara T, Tada M, Mikata R, Sakai Y, Sugiyama H, Saito M, Kurosawa J, Nishikawa T, Yoshitomi H, Ohtsuka M, Miyazaki M, Yokosuka O. Comparison of branch duct and main pancreatic duct mural nodules in intraductal papillary mucinous neoplasm. Pancreas. 2013 Oct;42(7):1193-5.
20. Suzuki E, Chiba T, Yokosuka O. Oncofetal gene SALL4 in aggressive hepatocellular carcinoma. N Engl J Med. 2013 Sep 19;369(12):1170-1.
21. Maruyama H, Kamezaki H, Takahashi M, Okugawa H, Yokosuka O. The Potential of Transabdominal 3D Color Doppler Ultrasonography for Diagnosis of Gastric Varices. J Clin Gastroenterol. 2013 Sep 16. [Epub ahead of print]
22. Kanda T, Jiang X, Nakamoto S, Nakamura M, Miyamura T, Wu S, Yokosuka O. Different effects of three interferons L on Toll-like receptor-related gene expression in HepG2 cells. Cytokine. 2013 Nov;64(2):577-83.
23. Nakano M, Kawaguchi T, Nakamoto S, Kawaguchi A, Kanda T, Imazeki F, uromatsu R, Sumie S, Satani M, Yamada S, Torimura T, Kakuma T, Yokosuka O, Sata M. Effect of occult hepatitis B virus infection on the early-onset of hepatocellular carcinoma in patients with hepatitis C virus infection. Oncol Rep. 2013 Nov;30(5):2049-55.
24. Nishikawa T, Tsuyuguchi T, Sakai Y, Sugiyama H, Kishimoto T, Ohtsuka M, Miyazaki M, Yokosuka O. Preoperative assessment of longitudinal extension of cholangiocarcinoma with peroral video-cholangioscopy: A prospective study. Dig Endosc. 2013 Aug 25.. [Epub ahead of print]
25. Sazuka S, Katsuno T, Nakagawa T, Saito M, Saito K, Maruoka D, Matsumura T, Arai M, Miyauchi H, Matsubara H, Yokosuka O. Fibrocytes Are Involved in Inflammation as well as Fibrosis in the Pathogenesis of Crohn's Disease. Dig Dis Sci. 2014 Apr;59(4):760-8.. Epub 2013 Aug 22.
26. Fujiwara K, Ohtsuka M, Yokosuka O. Radiologic and histologic heterogeneity in a case of autoimmune acute liver failure. Clin Gastroenterol Hepatol. 2014 Mar;12(3):e19-20. 2013.08.011. Epub 2013 Aug 17.
27. Kondo R, Nakashima O, Sata M, Imazeki F, Yokosuka O, Tanikawa K, Kage M, Yano H; The Liver Cancer Study Group of Kyushu. Pathological characteristics of patients who develop hepatocellular carcinoma with negative results of both serous hepatitis B surface antigen and hepatitis C virus antibody. Hepatol Res. 2013 Aug 13. [Epub ahead of print]
28. Saito T, Chiba T, Yuki K, Zen Y, Oshima M, Koide S, Motoyama T, Ogasawara S, Suzuki E, Ooka Y, Tawada A, Tada M, Kanai F, Takiguchi Y, Iwama A, Yokosuka O. Metformin, a diabetes drug, eliminates tumor-initiating hepatocellular carcinoma cells. PLoS One. 2013 Jul 29;8(7)
29. Sakai Y, Tsuyuguchi T, Sugiyama H, Nishikawa T, Kurosawa J, Saito M, Tawada K, Mikata R, Tada M, Ishihara T, Yokosuka O. Hypertonic saline-epinephrine local injection therapy for post-endoscopic sphincterotomy bleeding: removal of blood clots using pure ethanol local injection. Surg Laparosc Endosc Percutan Tech. 2013 Aug;23(4):e156-9.
30. Maruyama H, Kamezaki H, Kondo T, Sekimoto T, Shimada T, Takahashi M, Okugawa H, Yokosuka O. Effects of inferior mesenteric vein flow in patients with cirrhosis. Clin Gastroenterol Hepatol. 2013 Dec;11(12):1648-54.
31. Semba T, Nishimura M, Nishimura S, Ohara O, Ishige T, Ohno S, Nonaka K, Sogawa K, Satoh M, Sawai S, Matsushita K, Imazeki F, Yokosuka O, Nomura F. The FLS (fatty liver Shionogi) mouse reveals local expressions of lipocalin-2, CXCL1 and CXCL9 in the liver with non-alcoholic steatohepatitis. BMC Gastroenterol. 2013 Jul 23;13:120.
32. Tsuboi M, Arai M, Maruoka D, Matsumura T, Nakagawa T, Katsuno T, Yokosuka O. Utility and stability of transnasal endoscopy for examination of the pharynx - a prospective study and comparison with transoral endoscopy. Int J Med Sci. 2013 Jul 3;10(9):1085-91.
33. Mandai Y, Takahashi D, Hase K, Obata Y, Furusawa Y, Ebisawa M, Nakagawa T, Sato T, Katsuno T, Saito Y, Shimaoka T, Yokosuka O, Yokote K, Ohno H. Distinct Roles for CXCR6(+) and CXCR6(-) CD4(+) T Cells in the Pathogenesis of Chronic Colitis. PLoS One. 2013 Jun 19;8(6):e65488.
34. Nishikawa T, Tsuyuguchi T, Sakai Y, Sugiyama H, Tawada K, Mikata R, Tada M, Ishihara T, Miyazaki M, Yokosuka O. Factors affecting the accuracy of endoscopic transpapillary sampling methods for bile duct cancer. Dig Endosc. 2014 Mar;26(2):276-81. Epub 2013 Jul 5.
35. Nakamura M, Kanda T, Miyamura T, Wu S, Nakamoto S, Yokosuka O. Alanine aminotransferase elevation during peginterferon alpha-2a or alpha-2b plus ribavirin treatment. Int J Med Sci. 2013 Jun 15;10(8):1015-21.
36. Miyamura T, Kanda T, Minemura S, Nakamura M, Nakamoto S, Jiang X, Wu S, Yasui S, Arai M, Yokosuka O. Acute liver failure associated with propylthiouracil in a pregnant 26-year-old woman. Case Rep Gastroenterol. 2013 May 25;7(2):240-4.
37. Tsuboi M, Arai M, Maruoka D, Matsumura T, Nakagawa T, Katsuno T, Yokosuka O. Utility of unsedated transnasal endoscopy for pharyngeal observation during esophagogastroduodenoscopy. A prospective study to assess cardiopulmonary function. Scand J Gastroenterol. 2013 Jul;48(7):884-9.
38. Maruyama H, Kamezaki H, Kondo T, Sekimoto T, Shimada T, Takahashi M, Yokosuka O. The application of transabdominal 3D ultrasound for the diagnosis of gastric varices: a preliminary study. Eur J Radiol. 2013 Sep;82(9):e400-4. Epub 2013 May 22.
39. Kanda T, Kato K, Tsubota A, Takada N, Nishino T, Mikami S, Miyamura T, Maruoka D, Wu S, Nakamoto S, Arai M, Fujiwara K, Imazeki F, Yokosuka O.  Platelet count and sustained virological response in hepatitis C treatment. World J Hepatol. 2013 Apr 27;5(4):182-8.
40. Okimoto K, Ogasawara S, Chiba T, Kanai F, Yokota H, Motoyama T, Suzuki E, Ooka Y, Tawada A, Iwadate Y, Saeki N, Yokosuka O. Successful resection of intracranial metastasis of hepatocellular carcinoma. Case Rep Gastroenterol. 2013 Mar 28;7(1):182-7.
41. Fujiwara K, Yasui S, Yonemitsu Y, Mikata R, Arai M, Kanda T, Imazeki F, Oda S, Yokosuka O. Efficacy of high-dose corticosteroid in the early stage of viral acute liver failure. Hepatol Res. 2013 Apr 26.
42. Jiang X, Kanda T, Tanaka T, Wu S, Nakamoto S, Imazeki F, Yokosuka O. Lipopolysaccharide blocks induction of unfolded protein response in human hepatoma cell lines. Immunol Lett. 2013 Apr;152(1):8-15.
43. Kanda T, Yokosuka O, Omata M. Treatment of hepatitis C virus infection in the future. Clin Transl Med. 2013 Apr 11;2(1):9.
44. Miyauchi T, Kanda T, Shinozaki M, Kamezaki H, Wu S, Nakamoto S, Kato K, Arai M, Mikami S, Sugiura N, Kimura M, Goto N, Imazeki F, Yokosuka O. Efficacy of lamivudine or entecavir against virological rebound after achieving HBV DNA negativity in chronic hepatitis B patients. Int J Med Sci. 2013;10(6):647-52.
45. Matsumura T, Arai M, Yoshikawa M, Sudo K, Nakamura K, Katsuno T, Kanai F, Yamaguchi T, Yokosuka O. Changes in plasma ghrelin and serum leptin levels after Cisplatin-based transcatheter arterial infusion chemotherapy for hepatocellular arcinoma. ISRN Gastroenterol. Epub 2013 Mar 7.
46. Kamezaki H, Kanda T, Arai M, Wu S, Nakamoto S, Chiba T, Maruyama H, Fujiwara K, Kanai F, Imazeki F, Nomura F, Yokosuka O. Adherence to medication is a more important contributor to viral breakthrough in chronic hepatitis B patients treated with entecavir than in those with Lamivudine. Int J Med Sci. 2013;10(5):567-74. Epub 2013 Mar 15.
47. Haga Y, Chiba T, Ohira G, Kanai F, Yokota H, Motoyama T, Ogasawara S, Suzuki E, Ooka Y, Tawada A, Miyauchi H, Matubara H, Yokosuka O. Simultaneous resection of disseminated hepatocellular carcinoma and colon cancer. Case Rep Gastroenterol. 2013 Jan;7(1):37-43. Epub 2013 Jan 23.
48. Sekimoto T, Maruyama H, Kondo T, Shimada T, Takahashi M, Yokosuka O, Otsuka M, Miyazaki M, Mine Y. Virtual laparoscopy: Initial experience with three-dimensional ultrasonography to characterize hepatic surface features. Eur J Radiol. 2013 Jun;82(6):929-34. Epub 2013 Feb 28.
49. Maruyama H, Takahashi M, Shimada T, Sekimoto T, Kamesaki H, Kanai F, Yokosuka O. Pretreatment microbubble-induced enhancement in hepatocellular carcinoma predicts intrahepatic distant recurrence after radiofrequency ablation. AJR Am J Roentgenol. 2013 Mar;200(3):570-7.
50. Katsuno T, Saito K, Yokosuka O. Letter: factors that may predict response to ciclosporin in ulcerative colitis - authors' reply. Aliment Pharmacol Ther. 2013 Mar;37(6):655.
51. Sogawa K, Noda K, Umemura H, Seimiya M, Kuga T, Tomonaga T, Nishimura M, Kanai F, Imazeki F, Takizawa H, Yoneda M, Nakajima A, Tsutsumi M, Yokosuka O, Nomura F. Serum fibrinogen alpha C-chain 5.9 kDa fragment as a biomarker for early detection of hepatic fibrosis related to hepatitis C virus. Proteomics Clin Appl. 2013 Jun;7(5-6):424-31. Epub 2013 May 17.
52. Maruyama H, Okugawa H, Takahashi M, Yokosuka O. De novo portal vein thrombosis in virus-related cirrhosis: predictive factors and long-term outcomes. Am J Gastroenterol. 2013 Apr;108(4):568-74. Epub 2013 Feb 5.
53. Minemura S, Matsumura T, Arai M, Oyamada A, Saito K, Sazuka S, Tsuboi M, Maruoka D, Tanaka T, Nakagawa T, Katsuno T, Ishida K, Matsumiya G, Yokosuka O. A primary arterio enteric fistula with Takayasu arteritis. Intern Med. 2013;52(3):359-62. Epub 2013 Feb 1. PubMed PMID: 23370745.
54. Sakai Y, Tsuyuguchi T, Hirata N, Nakaji S, Shimura K, Fujimoto T, Tsuchiya S, Nishino T, Nishikawa T, Sugiyama H, Yokosuka O. Can endoscopic sphincterotomy be performed safely in elderly patients aged 80 years or older with pancreatic and biliary diseases? Hepatogastroenterology. 2013 Sep;60(126):1251-6.
55. Maruoka D, Arai M, Kishimoto T, Matsumura T, Inoue M, Nakagawa T, Watanabe Y, Katsuno T, Tsuyuguchi T, Imazeki F, Yokosuka O. Clinical outcomes of endoscopic resection for nonampullary duodenal high-grade dysplasia and intramucosal carcinoma. Endoscopy. 2013;45(2):138-41.. Epub 2013 Jan 15.
56. Kanda T, Nakamoto S, Nishino T, Takada N, Tsubota A, Kato K, Miyamura T, Maruoka D, Wu S, Tanaka T, Arai M, Mikami S, Fujiwara K, Imazeki F, Yokosuka O. Peginterferon Alfa-2a plus ribavirin in Japanese patients infected with hepatitis C virus genotype 2 who failed previous interferon therapy. Int J Med Sci. 2013;10(1):43-9. Epub 2012 Dec 10.
57. Nishikawa T, Tsuyuguchi T, Sakai Y, Sugiyama H, Miyazaki M, Yokosuka O. Comparison of the diagnostic accuracy of peroral video-cholangioscopic visual findings and cholangioscopy-guided forceps biopsy findings for indeterminate biliary lesions: a prospective study. Gastrointest Endosc. 2013 Feb;77(2):219-26. Epub 2012 Dec 8.
58. Ooka Y, Kanai F, Okabe S, Ueda T, Shimofusa R, Ogasawara S, Chiba T, Sato Y, Yoshikawa M, Yokosuka O. Gadoxetic acid-enhanced MRI compared with CT during angiography in the diagnosis of hepatocellular carcinoma. Magn Reson Imaging. 2013 Jun;31(5):748-54. Epub 2012 Dec 5.
59. Katsuno T, Saito K, Yokosuka O. Letter: should colectomy be the end-point to evaluate the effectiveness of drug therapies in severe ulcerative colitis? Authors' reply. Aliment Pharmacol Ther. 2013 Jan;37(1):161.
60. Saito M, Ishihara T, Tada M, Tsuyuguchi T, Mikata R, Sakai Y, Tawada K, Sugiyama H, Kurosawa J, Otsuka M, Uchida Y, Uchiyama K, Miyazaki M, Yokosuka O. Use of F-18 fluorodeoxyglucose positron emission tomography with dual-phase I  maging to identify intraductal papillary mucinous neoplasm. Clin Gastroenterol Hepatol. 2013 Feb;11(2):181-6. Epub 2012 Nov 6.
61. Takahashi M, Maruyama H, Shimada T, Kamezaki H, Sekimoto T, Kanai F, Yokosuka O. Characterization of hepatic lesions (≤ 30 mm) with liver-specific contrast agents: a comparison between ultrasound and magnetic resonance imaging. Eur J Radiol. 2013 Jan;82(1):75-84. Epub 2012 Oct 29.
62. Sakai Y, Tsuyuguchi T, Kato K, Sugiyama H, Nishikawa T, Takahashi M, Yokosuka O. Clinical usefulness of doripenem (DRPM), a carbapenem antimicrobial drug, for the treatment of patients with acute cholangitis: retrospective study. Int J Clin Pharmacol Ther. 2013 Jan;51(1):19-25.
63. Mikata R, Ishihara T, Tada M, Tawada K, Saito M, Kurosawa J, Sugiyama H, Sakai Y, Tsuyuguchi T, Miyazaki M, Yokosuka O. Clinical usefulness of repeated pancreatic juice cytology via endoscopic naso-pancreatic drainage tube in patients with pancreatic cancer. J Gastroenterol. 2013 Jul;48(7):866-73. Epub 2012 Oct 10.
64. Sugiyama H, Tsuyuguchi T, Sakai Y, Nisikawa T, Miyazaki M, Yokosuka O. Preoperative drainage for distal biliary obstruction: endoscopic stenting or nasobiliary drainage? Hepatogastroenterology. 2013 Mar-Apr;60(122):231-4.
65. Hata S, Arai M, Maruoka D, Tanaka T, Matsumura T, Suzuki T, Nakagawa T, Katsuno T, Imazeki F, Yokosuka O. Intragastric acidity during the first day following administration of low-dose proton pump inhibitors: a randomized crossover study. Clin Res Hepatol Gastroenterol. 2013 Jun;37(3):296-301. Epub 2012 Sep 5.
66. Izumi N, Asahina Y, Kurosaki M, Yamada G, Kawai T, Kajiwara E, Okamura Y, Takeuchi T, Yokosuka O, Kariyama K, Toyoda J, Inao M, Tanaka E, Moriwaki H, Adachi H, Katsushima S, Kudo M, Takaguchi K, Hiasa Y, Chayama K, Yatsuhashi H,Oketani M, Kumada H. Inhibition of hepatocellular carcinoma by PegIFNα-2a in patients with chronic hepatitis C: a nationwide multicenter cooperative study. J Gastroenterol. 2013 Mar;48(3):382-90. Epub 2012 Aug 9.
67. Seimiya M, Ohno S, Yamamoto H, Fujiwara K, Yoshida T, Sawabe Y, Sogawa K, Matsushita K, Yokosuka O, Nomura F. Child-Pugh score is altered by the albumin measurement method. Hepatology. 2013 May;57(5):2093-4. Epub 2012 Sep 24.
68. Sakai Y, Tsuyuguchi T, Sugiyama H, Nishikawa T, Kurosawa J, Saito M, Tawada K, Mikata R, Tada M, Ishihara T, Yokosuka O. Endoscopic sphincterotomy combined with large balloon dilation for removal of large bile duct stones. Hepatogastroenterology. 2013 Jan-Feb;60(121):58-64.
69. Hata S, Arai M, Suzuki T, Maruoka D, Matsumura T, Nakagawa T, Katsuno T, Imazeki F, Yokosuka O. Clinical significance of endoscopic ultrasound for gastric submucosal tumors. Clin Res Hepatol Gastroenterol. 2013 Apr;37(2):207-12. Epub 2012 May 23.
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2014年教室業績
1. Kanogawa N, Chiba T, Ogasawara S, Ooka Y, Suzuki E, Motoyama T, Saito T, Sekimoto T, Tawada A, Maruyama H, Yoshikawa M, Yokosuka O  Successful interventional treatment for arterioportal fistula caused by radiofrequency ablation for hepatocellular carcinoma.  Case Rep Oncol.7(3):833-9. 2014 Dec 19.
2. Seimiya M, Ohno S, Asano H, Fujiwara K, Yoshida T, Sawabe Y, Sogawa K, Ogawa M, Matsushita K, Yokosuka O, Nomura F. Change in albumin measurement method affects diagnosis of nephrotic syndrome.Clin Lab.60(10):1663-7. 2014.
3. Maruoka D, Arai M, Ishigami H, Okimoto K, Saito K, Minemura S, Matsumura T, Nakagawa T, Katsuno T, Yokosuka O. Sporadic nonampullary duodenal adenoma/carcinoma is associated with not only colon adenoma/carcinoma but also gastric cancer: association of location of duodenal lesions with comorbid diseases.Scand J Gastroenterol.50(3):333-40. 2015 Mar.
4. Miyamura T, Kanda T, Nakamoto S, Arai M, Nakamura M, Wu S, Jiang X, Sasaki R, Haga Y, Yasui S, Ooka Y, Chiba T, Imazeki F, Mikami S, Yokosuka O. IFNL4 ss469415590 Variant Is Associated with Treatment Response in Japanese HCV Genotype 1 Infected Individuals Treated with IFN-Including Regimens. Int J Hepatol. Epub 2014 Dec 8.
5. Sakai Y, Tsuyuguchi T, Kawaguchi Y, Hirata N, Nakaji S, Kitamura K, Mikami S, Fujimoto T, Ijima M, Kurihara E, Oana S, Nishino T, Tamura R, Sakamoto D, Nakamura M, Nishikawa T, Sugiyama H, Yoshida H, Mine T, Yokosuka O. Endoscopic papillary large balloon dilation for removal of bile duct stones. World J Gastroenterol.20(45):17148-54. 2014 Dec 7.
6. Suzuki E, Ooka Y, Chiba T, Kobayashi K, Kanogawa N, Motoyama T, Saito T, Ogasawara S, Tawada A, Yokosuka O. Incidental tumor necrosis caused by the interventional alteration of hepatic arterial flow in patients with advanced hepatocellular carcinoma. Clin J Gastroenterol.8(1):41-6. 2015 Feb Epub 2014 Dec 7.
7. Arai M, Matsumura T, Okimoto K, Oyamada A, Saito K, Minemura S, Maruoka D, Tanaka T, Nakagawa T, Katsuno T, Yokosuka O. Two-week treatment with proton pump inhibitor is sufficient for healing post endoscopic submucosal dissection ulcers. World J Gastroenterol.20(43):16318-22. 2014 Nov 21.
8. Nakamoto S, Kanda T, Nakaseko C, Sakaida E, Ohwada C, Takeuchi M, Takeda Y, Mimura N, Iseki T, Wu S, Arai M, Imazeki F, Saito K, Shirasawa H, Yokosuka O. Reactivation of hepatitis B virus in hematopoietic stem cell transplant recipients in Japan: efficacy of nucleos(t)ide analogues for prevention and treatment.Int J Mol Sci.15(11):21455-67. 2014 Nov 21.
9. Jiang X, Kanda T, Wu S, Nakamoto S, Wakita T, Shirasawa H, Yokosuka O. Hepatitis C virus nonstructural protein 5A inhibits thapsigargin-induced apoptosis. PLoS One.9(11) 2014 Nov 19.
10. Nakagawa T, Katsuno T, Mandai Y, Saito M, Yoshihama S, Saito K, Minemura S, Maruoka D, Matsumura T, Arai M, Yokosuka O. A Case of Blind Loop Syndrome Caused by Infection with Giardia duodenalis Diagnosed with Double Balloon Enteroscopy. Case Rep Gastroenterol. 8(3):276-81. 2014 Sep 23.
11. Kawaguchi T, Nagao Y, Abe K, Imazeki F, Honda K, Yamasaki K, Miyanishi K, Taniguchi E, Kakuma T, Kato J, Seike M, Yokosuka O, Ohira H, Sata M  Effects of branched-chain amino acids and zinc-enriched nutrients on prognosticators in HCV-infected patients: a multicenter randomized controlled trial. Mol Med Rep.11(3):2159-66 2015 Mar. 2014. Epub 2014 Nov 13.
12. Saito K, Katsuno T, Nakagawa T, Minemura S, Oyamada A, Kanogawa N, Saito M, Yoshihama S, Maruoka D, Matsumura T, Arai M, Tohma T, Miyauchi H, Matsubara H, Yokosuka O. Severe diffuse duodenitis successfully treated with intravenous tacrolimus after colectomy for ulcerative colitis.Intern Med. 53(21):2477-81. Epub 2014 Nov 1
13. Shimada T, Maruyama H, Kondo T, Sekimoto T, Takahashi M, Yokosuka O. Impact of splenic circulation: non-invasive microbubble-based assessment of portal hemodynamics.Eur Radiol. (3):812-20. 2015 Mar;25 Epub 2014 Nov 1.
14. Fujiwara K, Yasui S, Yonemitsu Y, Arai M, Kanda T, Nakano M, Oda S, Yokosuka O. Fixed point observation of etiology of acute liver failure according to the novel Japanese diagnostic criteria. J Hepatobiliary Pancreat Sci. (3):225-9. 2015 Mar;22 Epub 2014 Oct 22.
15. Jiang X, Kanda T, Nakamoto S, Haga Y, Sasaki R, Nakamura M, Wu S, Mikata R, Yokosuka O. Knockdown of glucose-regulated protein 78 enhances poly(ADP-ribose) polymerase cleavage in human pancreatic cancer cells exposed to endoplasmic reticulum stress.Oncol Rep.32(6):2343-82014 Dec. Epub 2014 Oct 6.
16. Ooka Y, Chiba T, Ogasawara S, Motoyama T, Suzuki E, Tawada A, Kanai F, Yokosuka O. Partial splenic embolization with transarterial chemoembolization in patients with hepatocellular carcinoma accompanied by thrombocytopenia. Biomed Res Int. Epub 2014 Sep 15.
17. Matsumura T, Arai M, Maruoka D, Okimoto K, Minemura S, Ishigami H, Saito K, Nakagawa T, Katsuno T, Yokosuka O. Risk factors for early and delayed post-operative bleeding after endoscopic submucosal dissection of gastric neoplasms, including patients with continued use of antithrombotic agents.BMC Gastroenterol.;14:172. 2014 Oct 3.
18. Nishikawa T, Tsuyuguchi T, Sakai Y, Yokosuka O. Safe recovery of a fully fractured basket in the bile duct using endoscopic papillary large balloon dilation. Endoscopy. Epub 2014 Sep 25.
19. Fujiwara K, Yasui S, Yonemitsu Y, Arai M, Kanda T, Nakano M, Oda S, Yokosuka O.Importance of the poor prognosis of severe and fulminant hepatitis in the elderly in an era of a highly aging society: Analysis in a Japanese center. Hepatol Res. 2014 Sep 19.
20. Sakai Y, Tsuyuguchi T, Yokosuka O. Clinical usefulness and current problems of pancreatic duct stenting for preventing post-ERCP pancreatitis. World J Clin Cases.2(9):426-31. 2014 Sep 16.
21. Ogasawara S, Chiba T, Ooka Y, Kanogawa N, Motoyama T, Suzuki E, Tawada A, Kanai F, Yoshikawa M, Yokosuka O. Efficacy of sorafenib in intermediate-stage hepatocellular carcinoma patients refractory to transarterial chemoembolization. Oncology87(6):330-41. 2014 Epub 2014 Sep 6.
22. Omata M, Nishiguchi S, Ueno Y, Mochizuki H, Izumi N, Ikeda F, Toyoda H, Yokosuka O, Nirei K, Genda T, Umemura T, Takehara T, Sakamoto N, Nishigaki Y, Nakane K, Toda N, Ide T, Yanase M, Hino K, Gao B, Garrison KL, Dvory-Sobol H, Ishizaki A, Omote M, Brainard D, Knox S, Symonds WT, McHutchison JG, Yatsuhashi H, Mizokami M. Sofosbuvir plus ribavirin in Japanese patients with chronic genotype 2 HCV infection: an open-label, phase 3 trial. J Viral Hepat. (11):762-8. 2014 Nov;21 Epub 2014 Sep 8.
23. Nishikawa T, Tsuyuguchi T, Sakai Y, Sugiyama H, Sakamoto D, Nakamura M, Yokosuka O. Old age is associated with increased severity of complications in endoscopic biliary stone removal. Dig Endosc.26(4):569-76. 2014 Jul.
24. Tawada A, Chiba T, Ooka Y, Kanogawa N, Motoyama T, Saito T, Ogasawara S, Suzuki E, Maruyama H, Kanai F, Yoshikawa M, Yokosuka O. Efficacy of transarterial chemoembolization targeting portal vein tumor thrombus in patients with hepatocellular carcinoma. Anticancer Res.34(8):4231-7. 2014 Aug.
25. Kanda T, Jiang X, Yokosuka O. Androgen receptor signaling in hepatocellular carcinoma and pancreatic cancers.World J Gastroenterol.20(28):9229-36. 2014 Jul 28.
26. Tsuyuguchi T, Miyakawa K, Sugiyama H, Sakai Y, Nishikawa T, Sakamoto D, Nakamura M, Yasui S, Mikata R, Yokosuka O. Ten-year long-term results after non-surgical management of hepatolithiasis, including cases with choledochoenterostomy. J Hepatobiliary Pancreat Sci.21(11):795-800. 2014 Nov Epub 2014 Jul 29.
27. Tawada A, Kanda T, Oide T, Tsuyuguchi T, Imazeki F, Nakatani Y, Yokosuka O. 18F-fluorodeoxyglucose positron emission tomography might be useful for diagnosis of hepatic amyloidosis. Int Med Case Rep J.7:103-9. 2014 Jun 20.
28. Sekimoto T, Maruyama H, Kiyono S, Kondo T, Shimada T, Ishibashi H, Takahashi M, Yokosuka O, Yamaguchi T. Hepatic filling rate of a microbubble agent: a novel predictor of long-term outcomes in patients with cirrhosis.b  Ultrasound Med Biol.40(9):2082-8. 2014 Sep. Epub 2014 Jul 10.
29. Maruoka D, Arai M, Tanaka T, Okimoto K, Oyamada A, Minemura S, Tsuboi M, Matsumura T, Nakagawa T, Kanda T, Katsuno T, Imazeki F, Yokosuka O. Mosapride citrate increases postprandial glucagon-like peptide-1, insulin, and gene expression of sweet taste receptors. Dig Dis Sci.60(2):345-53. 2015 Feb Epub 2014 Jul 10.
30. Jiang X, Kanda T, Wu S, Nakamoto S, Saito K, Shirasawa H, Kiyohara T, Ishii K, Wakita T, Okamoto H, Yokosuka O. Suppression of La antigen exerts potential antiviral effects against hepatitis A virus. PLoS One.9(7) 2014 Jul 7.
31. Jiang X, Kanda T, Wu S, Nakamura M, Miyamura T, Nakamoto S, Banerjee A, Yokosuka O. Regulation of microRNA by hepatitis B virus infection and their possible association with control of innate immunity.World J Gastroenterol.20(23):7197-206. 2014 Jun 21.
32. Ohtsuka M, Shimizu H, Kato A, Yoshitomi H, Furukawa K, Tsuyuguchi T, Sakai Y, Yokosuka O, Miyazaki M. Intraductal papillary neoplasms of the bile duct. Int J Hepatol. 2014 Epub 2014 May 18.
33. Kanda T, Nakamoto S, Yasui S, Nakamura M, Miyamura T, Wu S, Jiang X, Arai M, Imazeki F, Yokosuka O. Occurrence and Recurrence of Hepatocellular Carcinoma Were Not Rare Events during Phlebotomy in Older Hepatitis C Virus-Infected Patients. Case Rep Oncol. 7(2):288-96. 2014 May 8.
34. Kanda T, Nakamoto S, Wu S, Yokosuka O. New treatments for genotype 1 chronic hepatitis C - focus on simeprevir.  Ther Clin Risk Manag.10:387-94. 2014 May 24.
35. Kondo T, Maruyama H, Kiyono S, Sekimoto T, Shimada T, Takahashi M, Okugawa H, Kobayashi S, Yoshizumi H, Yokosuka O. Similarities and differences in the clinical features between cardia varices and esophageal varices. J Gastroenterol Hepatol.29(11):1911-8. 2014 Nov.
36. Maruyama H, Takahashi M, Sekimoto T, Shimada T, Yokosuka O.Linoleate appears to protect against palmitate-induced inflammation in Huh7 cells. Lipids Health Dis.13:78. 2014 May 13.
37. Hayashi M, Kanda T, Nakamura M, Miyamura T, Yasui S, Nakamoto S, Wu S, Arai M, Imazeki F, Yokosuka O. Acute liver injury in a patient with alcohol dependence: a case resembling autoimmune hepatitis or drug-induced liver injury. Case Rep Gastroenterol.8(1):129-33. 2014 Apr 5.
38. Chiba T, Saito T, Yuki K, Zen Y, Koide S, Kanogawa N, Motoyama T, Ogasawara S, Suzuki E, Ooka Y, Tawada A, Otsuka M, Miyazaki M, Iwama A, Yokosuka O. Histone lysine methyltransferase SUV39H1 is a potent target for epigenetic therapy of hepatocellular carcinoma. Int J Cancer.136(2):289-98. 2015 Jan 15 Epub 2014 May 30.
39. Saito T, Chiba T, Suzuki E, Shinozaki M, Goto N, Kanogawa N, Motoyama T, Ogasawara S, Ooka Y, Tawada A, Kanda T, Miyazaki M, Yokosuka O. Effect of previous interferon-based therapy on recurrence after curative treatment of hepatitis C virus-related hepatocellular carcinoma. Int J Med Sci.11(7):707-12. 2014 May 7.
40. Yasui S, Fujiwara K, Nakamura M, Miyamura T, Yonemitsu Y, Mikata R, Arai M, Kanda T, Imazeki F, Oda S, Yokosuka O. Virological efficacy of combination therapy with corticosteroid and nucleoside analogue for severe acute exacerbation of chronic hepatitis B. J Viral Hepat.22(2):94-102. 2015 Feb Epub 2014 Apr 21.
41. Tawada A, Chiba T, Ooka Y, Yokota H, Kanogawa N, Motoyama T, Saito T, Ogasawara S, Suzuki E, Hanari N, Matsubara H, Saeki N, Kambe M, Kishimoto T, Nakatani Y, Yokosuka O. Intracranial metastasis in a patient with hepatocellular carcinoma and gastric cancer. Case Rep Oncol.7(1):199-203. 2014 Mar 14 eCollection 2014 Jan.
42. Naito A, Terada J, Tanabe N, Sugiura T, Sakao S, Kanda T, Yokosuka O, Tatsumi KAutoimmune hepatitis in a patient with pulmonary arterial hypertension treated with endothelin receptor antagonists.Intern Med.53(7):771-5. 2014 Epub 2012 Mar 1.
43. Nakamoto S, Kanda T, Wu S, Shirasawa H, Yokosuka O. Hepatitis C virus NS5A inhibitors and drug resistance mutations. World J Gastroenterol.20(11):2902-12. 2014 Mar 21.
44. Maruyama H, Kiyono S, Kamesaki H, Kondo T, Sekimoto T, Yokosuka O. Saline-enhanced ultrasonography: prediction of X-ray appearance of hepatic venography in patients with cirrhosis. Scand J Gastroenterol. 49(5):625-31. 2014 May Epub 2014 Mar 20.
45. Matsumura T, Arai M, Saito K, Okimoto K, Saito M, Minemura S, Oyamada A, Maruoka D, Nakagawa T, Watabe H, Katsuno T, Yokosuka O. Predictive factor of re-bleeding after negative capsule endoscopy for obscure gastrointestinal bleeding: over 1-year follow-up study. Dig Endosc.26(5):650-8. 2014 Sep Epub 2014 Mar 13.
46. Ooka Y, Chiba T, Ogasawara S, Arai K, Suzuki E, Tawada A, Yamashita T, Kanai F, Kaneko S, Yokosuka O. A phase I/II study of S-1 with sorafenib in patients with advanced hepatocellular carcinoma. Invest New Drugs.32(4):723-8. 2014 Aug Epub 2014 Mar 7.
47. Nishikawa T, Tsuyuguchi T, Ohyama H, Watanabe Y, Koseki H, Sakai Y, Sugiyama H, Sakamoto D, Kiyono S, Nakamura M, Yokosuka O Endoscopy-guided laser lithotripsy for a difficult-to-crush enterolith..Gastrointest Endosc.80(4):729-30. 2014 Oct Epub 2014 Mar 1.
48. Fujiwara K, Yasui S, Yokosuka O. Historical, present, and future significance of corticosteroid in the treatment of acute liver failure. Hepatology.60(4):1447-8. 2014 Oct  Epub 2014 Aug 25.
49. Tanaka T, Arai M, Jiang X, Sugaya S, Kanda T, Fujii K, Kita K, Sugita K, Imazeki F, Miyashita T, Kaneda A, Yokosuka O. Downregulation of microRNA-431 by human interferon-β inhibits viability of medulloblastoma and glioblastoma cells via upregulation of SOCS6. Int J Oncol.44(5):1685-90. 2014 May Epub 2014 Feb 28.
50. Jiang X, Kanda T, Nakamoto S, Miyamura T, Wu S, Yokosuka O. Involvement of androgen receptor and glucose-regulated protein 78 kDa in human hepatocarcinogenesis. Exp Cell Res.;323(2):326-36. 2014 May 1 Epub 2014 Feb 26.
51. Hosokawa I, Shimizu H, Ohtsuka M, Kato A, Yoshitomi H, Furukawa K, Takayashiki T, Ishihara T, Yokosuka O, Miyazaki M. Preoperative diagnosis and surgical management for solid pseudopapillary neoplasm of the pancreas. J Hepatobiliary Pancreat Sci. 21(8):573-8. 2014 Aug Epub 2014 Feb 17.
52. Ogasawara S, Chiba T, Ooka Y, Kanogawa N, Motoyama T, Suzuki E, Tawada A, Yokosuka O. Is intra-patient sorafenib dose re-escalation safe and tolerable in patients with advanced hepatocellular carcinoma?Int J Clin Oncol.19(6):1029-36. 2014 Dec Epub 2014 Feb 13.
53. Yamato M, Kanda T, Yasui S, Nakamura M, Miyamura T, Arai M, Maruyama H, Yokosuka O.[Pulmonary nocardiosis associated with the treatment of severe liver injury]. Nihon Shokakibyo Gakkai Zasshi. 111(2):318-25. 2014 Feb.
54. Chiba T, Suzuki E, Yuki K, Zen Y, Oshima M, Miyagi S, Saraya A, Koide S, Motoyama T, Ogasawara S, Ooka Y, Tawada A, Nakatsura T, Hayashi T, Yamashita T, Kaneko S, Miyazaki M, Iwama A, Yokosuka O.Disulfiram eradicates tumor-initiating hepatocellular carcinoma cells in ROS-p38 MAPK pathway-dependent and -independent manners. PLoS One.9(1). 2014 Jan 13 eCollection 2014.
55. Izumi N, Yokosuka O, Kawada N, Osaki Y, Yamamoto K, Sata M, Ishikawa H, Ueki T, Hu W, McPhee F, Hughes EA, Kumada H. Daclatasvir combined with peginterferon alfa-2a and ribavirin in Japanese patients infected with hepatitis C genotype 1. Antivir Ther.19(5):501-10. 2014 Epub 2014 Jan 22.
56. McPhee F, Hernandez D, Zhou N, Yu F, Ueland J, Monikowski A, Chayama K, Toyota J, Izumi N, Yokosuka O, Kawada N, Osaki Y, Hughes EA, Watanabe H, Ishikawa H, Kumada H. Virological escape in HCV genotype-1-infected patients receiving daclatasvir plus ribavirin and peginterferon alfa-2a or alfa-2b.Antivir Ther.19(5):479-90. 2014 Epub 2014 Jan 22.
57. Wu S, Nakamoto S, Kanda T, Jiang X, Nakamura M, Miyamura T, Shirasawa H, Sugiura N, Takahashi-Nakaguchi A, Gonoi T, Yokosuka O. Ultra-deep sequencing analysis of the hepatitis A virus 5'-untranslated region among cases of the same outbreak from a single source. Int J Med Sci.11(1):60-4. 2013 Dec 20 eCollection 2014.
58. Maruyama H, Kamezaki H, Kondo T, Sekimoto T, Takahashi M, Yokosuka O. Sonographic and clinical features of collateral vessels at the splenic hilum in cirrhosis. Clin Radiol.69(3):e140-5. 2014 Mar Epub 2013 Dec 17.
59. Motoyama T, Ogasawara S, Chiba T, Higashide T, Yokota H, Kanogawa N, Suzuki E, Ooka Y, Tawada A, Irie R, Ochi S, Masuda Y, Uno T, Yokosuka O. Coronal reformatted CT images contribute to the precise evaluation of the radiofrequency ablative margin for hepatocellular carcinoma. Abdom Imaging.39(2):262-8. 2014 Apr.
60. Liu Y, Sogawa K, Sunaga M, Umemura H, Satoh M, Kazami T, Yoshikawa M, Tomonaga T, Yokosuka O, Nomura F. Increased concentrations of apo A-I and apo A-II fragments in the serum of patients with hepatocellular carcinoma by magnetic beads-assisted MALDI-TOF mass spectrometry. Am J Clin Pathol.141(1):52-61. 2014 Jan.
61. Sudo K, Ishihara T, Hirata N, Ozawa F, Ohshima T, Azemoto R, Shimura K, Nihei T, Nishino T, Nakagawa A, Nakamura K, Hara T, Tada M, Mikata R, Tawada K, Yokosuka O, Nakaji S, Yamaguchi T. Randomized controlled study of gemcitabine plus S-1 combination chemotherapy versus gemcitabine for unresectable pancreatic cancer. Cancer Chemother Pharmacol.73(2):389-96. 2014 Feb Epub 2013 Dec 10.
62. Tanaka T, Arai M, Minemura S, Oyamada A, Saito K, Jiang X, Tsuboi M, Sazuka S, Maruoka D, Matsumura T, Nakagawa T, Sugaya S, Kanda T, Katsuno T, Kita K, Kishimoto T, Imazeki F, Kaneda A, Yokosuka O. Expression level of sonic hedgehog correlated with the speed of gastric mucosa regeneration in artificial gastric ulcers. J Gastroenterol Hepatol.29(4):736-41. 2014 Apr.
63. Kondo T, Maruyama H, Sekimoto T, Shimada T, Takahashi M, Chiba T, Kanai F, Yokosuka O, Yamaguchi T. Natural history of postvascular-phase iso-enhanced lesions on the sonogram in chronic liver diseases.J Gastroenterol Hepatol.29(1):165-72. 2014 Jan.
64. Kondo T, Maruyama H, Sekimoto T, Shimada T, Takahashi M, Okugawa H, Yokosuka O, Yamaguchi T.Influence of paraumbilical vein patency on the portal hemodynamics of patients with cirrhosis. J Clin Gastroenterol.48(2):178-83. 2014 Feb.
65. Maruyama H, Kamezaki H, Takahashi M, Okugawa H, Yokosuka O. The potential of transabdominal 3D color doppler ultrasonography for diagnosis of gastric varices. J Clin Gastroenterol.48(7):629-342014 Aug.
66. Nishikawa T, Tsuyuguchi T, Sakai Y, Sugiyama H, Kishimoto T, Ohtsuka M, Miyazaki M, Yokosuka O.Preoperative assessment of longitudinal extension of cholangiocarcinoma with peroral video-cholangioscopy: a prospective study. Dig Endosc.26(3):450-7 2014 May Epub 2013 Aug 25.
67. Sazuka S, Katsuno T, Nakagawa T, Saito M, Saito K, Maruoka D, Matsumura T, Arai M, Miyauchi H, Matsubara H, Yokosuka O. Fibrocytes are involved in inflammation as well as fibrosis in the pathogenesis of Crohn's disease. Dig Dis Sci.59(4):760-8. 2014 Apr Epub 2013 Aug 22.
68. Fujiwara K, Ohtsuka M, Yokosuka O. Radiologic and histologic heterogeneity in a case of autoimmune acute liver failure. Clin Gastroenterol Hepatol.12(3):e19-20. 2014 Mar Epub 2013 Aug 17.
69. Kondo R, Nakashima O, Sata M, Imazeki F, Yokosuka O, Tanikawa K, Kage M, Yano H; Liver Cancer Study Group of Kyushu. Pathological characteristics of patients who develop hepatocellular carcinoma with negative results of both serous hepatitis B surface antigen and hepatitis C virus antibody. Hepatol Res.44(11):1039-46. 2014 Oct Epub 2013 Sep 17.
70. Nishikawa T, Tsuyuguchi T, Sakai Y, Sugiyama H, Tawada K, Mikata R, Tada M, Ishihara T, Miyazaki M, Yokosuka O. Factors affecting the accuracy of endoscopic transpapillary sampling methods for bile duct cancer. Dig Endosc.26(2):276-81. 2014 Mar Epub 2013 Jul 5.
71. Fujiwara K, Yasui S, Yonemitsu Y, Mikata R, Arai M, Kanda T, Imazeki F, Oda S, Yokosuka O.Efficacy of high-dose corticosteroid in the early stage of viral acute liver failure. Hepatol Res.44(5):491-501. Epub 2013 May 22. 2014 May.
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2015年教室業績
1. Kanaeda T, Ueda M, Arai M, Ishimura M, Kajiyama T, Hashiguchi N, Nakano M, Kondo Y, Hiranuma Y, Oyamada A, Yokosuka O, Kobayashi Y. Evaluation of periesophageal nerve injury after pulmonary vein isolation using the (13)C-acetate breath test. J Arrhythm. 2015 Dec;31(6):364-70. doi: 10.1016/j.joa.2015.06.004. PubMed PMID: 26702316; PubMed Central PMCID: PMC4672080.
2. Haga Y, Kanda T, Sasaki R, Nakamura M, Nakamoto S, Yokosuka O. Nonalcoholic fatty liver disease and hepatic cirrhosis: Comparison with viral hepatitis-associated steatosis. World J Gastroenterol. 2015 Dec 14;21(46):12989-95. doi: 10.3748/wjg.v21.i46.12989. Review. PubMed PMID: 26675364; PubMed Central PMCID: PMC4674717.
3. Nakamura M, Kanda T, Sasaki R, Haga Y, Jiang X, Wu S, Nakamoto S, Yokosuka O. MicroRNA-122 Inhibits the Production of Inflammatory Cytokines by Targeting the PKR Activator PACT in Human Hepatic Stellate Cells. PLoS One. 2015 Dec 4;10(12):e0144295. doi: 10.1371/journal.pone.0144295. PubMed PMID: 26636761; PubMed Central PMCID: PMC4670168.
4. Kanda T, Nakamoto S, Wu S, Nakamura M, Jiang X, Haga Y, Sasaki R, Yokosuka O. Direct-acting Antivirals and Host-targeting Agents against the Hepatitis A Virus. J Clin Transl Hepatol. 2015 Sep 28;3(3):205-10. doi: 10.14218/JCTH.2015.00016. Review. PubMed PMID: 26623267; PubMed Central PMCID: PMC4663202.
5. Kanda T, Yasui S, Nakamura M, Arai M, Sasaki R, Haga Y, Wu S, Nakamoto S, Okamoto H, Yokosuka O. Recent Trend of Hepatitis E Virus Infection in Chiba Area, Japan: 3 of 5 Cases with Rheumatoid Arthritis. Case Rep Gastroenterol. 2015 Oct 17;9(3):317-26. doi: 10.1159/000441387. PubMed PMID: 26600768; PubMed Central PMCID: PMC4649734.
6. Nakagawa T, Katsuno T, Noguchi Y, Mandai Y, Yoshihama S, Saito K, Maruoka D, Matsumura T, Arai M, Yokosuka O. Irsogladine Maleate Prevents Colitis in Interleukin-10 Gene-Deficient Mice by Reducing Interleukin-12 and -23 Production. Biol Pharm Bull. 2015;38(11):1681-8. doi: 10.1248/bpb.b15-00189. PubMed PMID: 26521820.
7. Suzuki E, Chiba T, Ogasawara S, Saito T, Kanogawa N, Motoyama T, Ooka Y, Tawada A, Maruyama H, Ogawa M, Yokosuka O. Tolvaptan treatment for patients with decompensated cirrhosis and advanced hepatocellular carcinoma. Hepatol Res. 2015 Oct;45(10):E161-2. doi: 10.1111/hepr.12465. PubMed PMID: 26510648.
8. Sakai Y, Tsuyuguchi T, Nishikawa T, Sugiyama H, Sasaki R, Sakamoto D, Watanabe Y, Nakamura M, Yasui S, Mikata R, Yokosuka O. New tapered metallic stent for unresectable malignant hilar bile duct obstruction. World J Clin Cases. 2015 Oct 16;3(10):887-93. doi: 10.12998/wjcc.v3.i10.887. PubMed PMID: 26488025; PubMed Central PMCID: PMC4607807.
9. Maruoka D, Arai M, Ishigami H, Okimoto K, Matsumura T, Nakagawa T, Yokosuka O. Cold polypectomy for nonampullary duodenal adenoma. Endoscopy. 2015;47 Suppl 1 UCTN:E477-8. doi: 10.1055/s-0034-1392668. PubMed PMID: 26479293.
10. Ogasawara S, Chiba T, Ooka Y, Suzuki E, Kanogawa N, Saito T, Motoyama T, Tawada A, Kanai F, Yokosuka O. Liver function assessment according to the Albumin-Bilirubin (ALBI) grade in sorafenib-treated patients with advanced hepatocellular carcinoma. Invest New Drugs. 2015 Dec;33(6):1257-62. doi: 10.1007/s10637-015-0292-9. PubMed PMID: 26462681.
11. Nishida N, Ohashi J, Sugiyama M, Tsuchiura T, Yamamoto K, Hino K, Honda M, Kaneko S, Yatsuhashi H, Koike K, Yokosuka O, Tanaka E, Taketomi A, Kurosaki M, Izumi N, Sakamoto N, Eguchi Y, Sasazuki T, Tokunaga K, Mizokami M. Effects of HLA-DPB1 genotypes on chronic hepatitis B infection in Japanese individuals. Tissue Antigens. 2015 Dec;86(6):406-12. doi: 10.1111/tan.12684. PubMed PMID: 26449183.
12. Fujiwara K, Yasui S, Yokosuka O. Corticosteroid and nucleoside analogue for hepatitis B virus-related acute liver failure. World J Gastroenterol. 2015 Sep 28;21(36):10485-6. doi: 10.3748/wjg.v21.i36.10485. PubMed PMID: 26420977; PubMed Central PMCID: PMC4579897.
13. Kanda T, Sasaki R, Nakamoto S, Haga Y, Nakamura M, Shirasawa H, Okamoto H, Yokosuka O. The sirtuin inhibitor sirtinol inhibits hepatitis A virus (HAV) replication by inhibiting HAV internal ribosomal entry site activity. Biochem Biophys Res Commun. 2015 Oct 23;466(3):567-71. doi: 10.1016/j.bbrc.2015.09.083. PubMed PMID: 26388050.
14. Kondo T, Maruyama H, Kiyono S, Sekimoto T, Shimada T, Takahashi M, Ogasawara S, Suzuki E, Ooka Y, Tawada A, Chiba T, Kanai F, Yokosuka O. Intensity-Based Assessment of Microbubble-Enhanced Ultrasonography: Phase-Related Diagnostic Ability for Cellular Differentiation of Hepatocellular Carcinoma. Ultrasound Med Biol. 2015 Dec;41(12):3079-87. doi: 10.1016/j.ultrasmedbio.2015.07.033. PubMed PMID: 26371403.
15. Nakamoto S, Imazeki F, Arai M, Yasui S, Nakamura M, Haga Y, Sasaki R, Kanda T, Shirasawa H, Yokosuka O. Effect of Hepatitis C Virus Genotype 1b Core and NS5A Mutations on Response to Peginterferon Plus Ribavirin Combination Therapy. Int J Mol Sci. 2015 Sep 7;16(9):21177-90. doi: 10.3390/ijms160921177. PubMed PMID: 26370958; PubMed Central PMCID: PMC4613248.
16. Sugiyama H, Tsuyuguchi T, Sakai Y, Mikata R, Yasui S, Watanabe Y, Sakamoto D, Nakamura M, Sasaki R, Senoo J, Kusakabe Y, Hayashi M, Yokosuka O. Current status of preoperative drainage for distal biliary obstruction. World J Hepatol. 2015 Aug 28;7(18):2171-6. doi: 10.4254/wjh.v7.i18.2171. Review. PubMed PMID: 26328029; PubMed Central PMCID: PMC4550872.
17. Fujiwara K, Yasui S, Yokosuka O. Appropriate diagnostic criteria for fulminant autoimmune hepatitis. Eur J Gastroenterol Hepatol. 2015 Oct;27(10):1230-1. doi: 10.1097/MEG.0000000000000441. PubMed PMID: 26327503.
18. Kanda T, Nakamoto S, Yokosuka O. Is the use of IL28B genotype justified in the era of interferon-free treatments for hepatitis C? World J Virol. 2015 Aug 12;4(3):178-84. doi: 10.5501/wjv.v4.i3.178. PubMed PMID: 26279979; PubMed Central PMCID: PMC4534809.
19. Kanda T, Nakamura M, Sasaki R, Yasui S, Nakamoto S, Haga Y, Jiang X, Wu S, Tawada A, Arai M, Imazeki F, Yokosuka O. Sustained Virological Response after 8-Week Treatment of Simeprevir with Peginterferon α-2a plus Ribavirin in a Japanese Female with Hepatitis C Virus Genotype 1b and IL28B Minor Genotype. Case Rep Gastroenterol. 2015 Jul 8;9(2):215-20. doi: 10.1159/000437138. PubMed PMID: 26269697; PubMed Central PMCID: PMC4520186.
20. Kondo T, Maruyama H, Sekimoto T, Shimada T, Takahashi M, Yokosuka O. Reversed portal flow: Clinical influence on the long-term outcomes in cirrhosis. World J Gastroenterol. 2015 Aug 7;21(29):8894-902. doi: 10.3748/wjg.v21.i29.8894. PubMed PMID: 26269679; PubMed Central PMCID: PMC4528032.
21. Suzuki E, Chiba T, Ooka Y, Ogasawara S, Tawada A, Motoyama T, Kanogawa N, Saito T, Yoshikawa M, Yokosuka O. Transcatheter arterial infusion for advanced hepatocellular carcinoma: Who are candidates? World J Gastroenterol. 2015 Aug 7;21(29):8888-93. doi: 10.3748/wjg.v21.i29.8888. PubMed PMID: 26269678; PubMed Central PMCID: PMC4528031.
22. Chiba T, Suzuki E, Saito T, Ogasawara S, Ooka Y, Tawada A, Iwama A, Yokosuka O. Biological features and biomarkers in hepatocellular carcinoma. World J Hepatol. 2015 Aug 8;7(16):2020-8. doi: 10.4254/wjh.v7.i16.2020. Review. PubMed PMID: 26261691; PubMed Central PMCID: PMC4528275.
23. Kanda T, Ogasawara S, Chiba T, Haga Y, Omata M, Yokosuka O. Current management of patients with hepatocellular carcinoma. World J Hepatol. 2015 Jul 28;7(15):1913-20. doi: 10.4254/wjh.v7.i15.1913. PubMed PMID: 26244066; PubMed Central PMCID: PMC4517151.
24. Sasaki R, Kanda T, Wu S, Nakamoto S, Haga Y, Jiang X, Nakamura M, Shirasawa H, Yokosuka O. Association between hepatitis B virus and MHC class I polypeptide-related chain A in human hepatocytes derived from human-mouse chimeric mouse liver. Biochem Biophys Res Commun. 2015 Sep 4;464(4):1192-5. doi: 10.1016/j.bbrc.2015.07.102. PubMed PMID: 26212443.
25. Maruyama H, Kondo T, Sekimoto T, Kiyono S, Shimada T, Takahashi M, Okugawa H, Yokosuka O. Hyponatremia: a significant factor in a poor prognosis for cirrhosis with Child A/B after variceal eradication. J Hepatobiliary Pancreat Sci. 2015 Oct;22(10):771-8. doi: 10.1002/jhbp.282. PubMed PMID: 26202665.
26. Jiang X, Kanda T, Wu S, Nakamoto S, Nakamura M, Sasaki R, Haga Y, Wakita T, Shirasawa H, Yokosuka O. Hepatitis C Virus Nonstructural Protein 5A Inhibits MG132-Induced Apoptosis of Hepatocytes in Line with NF-κB-Nuclear Translocation. PLoS One. 2015 Jul 2;10(7):e0131973. doi: 10.1371/journal.pone.0131973. Erratum in: PLoS One. 2015;10(7):e0134068. PubMed PMID: 26133378; PubMed Central PMCID: PMC4489642.
27. Maruyama H, Kondo T, Sekimoto T, Yokosuka O. Differential Clinical Impact of Ascites in Cirrhosis and Idiopathic Portal Hypertension. Medicine (Baltimore). 2015 Jul;94(26):e1056. doi: 10.1097/MD.0000000000001056. PubMed PMID: 26131820; PubMed Central PMCID: PMC4504543.
28. Saito T, Chiba T, Ogasawara S, Inoue M, Wakamatsu T, Motoyama T, Kanogawa N, Suzuki E, Ooka Y, Tawada A, Matsubara H, Yokosuka O. Fatal Diaphragmatic Hernia following Radiofrequency Ablation for Hepatocellular Carcinoma: A Case Report and Literature Review. Case Rep Oncol. 2015 May 28;8(2):238-45. doi: 10.1159/000431310. PubMed PMID: 26120308; PubMed Central PMCID: PMC4478306.
29. Tawada A, Kanda T, Yokosuka O. Current and future directions for treating hepatitis B virus infection. World J Hepatol. 2015 Jun 18;7(11):1541-52. doi: 10.4254/wjh.v7.i11.1541. Review. PubMed PMID: 26085913; PubMed Central PMCID: PMC4462692.
30. Nakamoto S, Kanda T, Shirasawa H, Yokosuka O. Antiviral therapies for chronic hepatitis C virus infection with cirrhosis. World J Hepatol. 2015 May 18;7(8):1133-41. doi: 10.4254/wjh.v7.i8.1133. Review. PubMed PMID: 26052402; PubMed Central PMCID: PMC4450190.
31. Sasaki R, Kanda T, Nakamoto S, Haga Y, Nakamura M, Yasui S, Jiang X, Wu S, Arai M, Yokosuka O. Natural interferon-beta treatment for patients with chronic hepatitis C in Japan. World J Hepatol. 2015 May 18;7(8):1125-32. doi: 10.4254/wjh.v7.i8.1125. Review. PubMed PMID: 26052401; PubMed Central PMCID: PMC4450189.
32. Minemura S, Tanaka T, Arai M, Okimoto K, Oyamada A, Saito K, Maruoka D, Matsumura T, Nakagawa T, Katsuno T, Kishimoto T, Yokosuka O. Gene expression profiling of laterally spreading tumors. BMC Gastroenterol. 2015 Jun 6;15:64. doi: 10.1186/s12876-015-0295-1. PubMed PMID: 26048755; PubMed Central PMCID: PMC4456718.
33. Maruyama H, Kondo T, Kiyono S, Sekimoto T, Takahashi M, Okugawa H, Yokosuka O. Relationship and interaction between serum sodium concentration and portal hemodynamics in patients with cirrhosis. J Gastroenterol Hepatol. 2015 Nov;30(11):1635-42. doi: 10.1111/jgh.13006. PubMed PMID: 25968445.
34. Kurosawa J, Tawada K, Mikata R, Ishihara T, Tsuyuguchi T, Saito M, Shimofusa R, Yoshitomi H, Ohtsuka M, Miyazaki M, Yokosuka O. Prognostic relevance of apparent diffusion coefficient obtained by diffusion-weighted MRI in pancreatic cancer. J Magn Reson Imaging. 2015 Dec;42(6):1532-7. doi: 10.1002/jmri.24939. PubMed PMID: 25946483.
35. Omata M, Kanda T, Yokosuka O, Crawford D, Al-Mahtab M, Wei L, Ibrahim A, Lau GK, Sharma BC, Hamid SS, Chuang WL, Dokmeci AK. Features of hepatitis C virus infection, current therapies and ongoing clinical trials in ten Asian Pacific countries. Hepatol Int. 2015 Oct;9(4):486-507. doi: 10.1007/s12072-015-9630-4. Review. PubMed PMID: 25941137.
36. Ogasawara S, Chiba T, Ooka Y, Kanogawa N, Motoyama T, Suzuki E, Tawada A, Azemoto R, Shinozaki M, Yoshikawa M, Yokosuka O. A prognostic score for patients with intermediate-stage hepatocellular carcinoma treated with transarterial chemoembolization. PLoS One. 2015 Apr 28;10(4):e0125244. doi: 10.1371/journal.pone.0125244. PubMed PMID: 25919025; PubMed Central PMCID: PMC4412579.
37. Sakai Y, Tsuyuguchi T, Sugiyama H, Sasaki R, Sakamoto D, Nakamura M, Watanabe Y, Nishikawa T, Yasui S, Mikata R, Yokosuka O. Endoscopic papillary large balloon dilation for bile duct stones in elderly patients. World J Clin Cases. 2015 Apr 16;3(4):353-9. doi: 10.12998/wjcc.v3.i4.353. PubMed PMID: 25879007; PubMed Central PMCID: PMC4391005.
38. Mizokami M, Yokosuka O, Takehara T, Sakamoto N, Korenaga M, Mochizuki H, Nakane K, Enomoto H, Ikeda F, Yanase M, Toyoda H, Genda T, Umemura T, Yatsuhashi H, Ide T, Toda N, Nirei K, Ueno Y, Nishigaki Y, Betular J, Gao B, Ishizaki A, Omote M, Mo H, Garrison K, Pang PS, Knox SJ, Symonds WT, McHutchison JG, Izumi N, Omata M. Ledipasvir and sofosbuvir fixed-dose combination with and without ribavirin for 12 weeks in treatment-naive and previously treated Japanese patients with genotype 1 hepatitis C: an open-label, randomised, phase 3 trial. Lancet Infect Dis. 2015 Jun;15(6):645-53. doi: 10.1016/S1473-3099(15)70099-X. PubMed PMID: 25863559.
39. Ogasawara S, Chiba T, Ooka Y, Kanogawa N, Saito T, Motoyama T, Suzuki E, Tawada A, Kanai F, Yokosuka O. Sorafenib treatment in Child-Pugh A and B patients with advanced hepatocellular carcinoma: safety, efficacy and prognostic factors. Invest New Drugs. 2015 Jun;33(3):729-39. doi: 10.1007/s10637-015-0237-3. PubMed PMID: 25861764.
40. Sekimoto T, Maruyama H, Kiyono S, Kondo T, Shimada T, Takahashi M, Yokosuka O, Yamaguchi T. Liver Stiffness: A Significant Relationship with the Waveform Pattern in the Hepatic Vein. Ultrasound Med Biol. 2015 Jul;41(7):1801-7. doi: 10.1016/j.ultrasmedbio.2015.03.002. PubMed PMID: 25858000.
41. Hirotsu Y, Kanda T, Matsumura H, Moriyama M, Yokosuka O, Omata M. HCV NS5A resistance-associated variants in a group of real-world Japanese patients chronically infected with HCV genotype 1b. Hepatol Int. 2015 Jul;9(3):424-30. doi: 10.1007/s12072-015-9624-2. PubMed PMID: 25791176.
42. Sato T, Kondo F, Ebara M, Sugiura N, Okabe S, Sunaga M, Yoshikawa M, Suzuki E, Ogasawara S, Shinozaki Y, Ooka Y, Chiba T, Kanai F, Kishimoto T, Nakatani Y, Fukusato T, Yokosuka O. Natural history of large regenerative nodules and dysplastic nodules in liver cirrhosis: 28-year follow-up study. Hepatol Int. 2015 Apr;9(2):330-6. doi: 10.1007/s12072-015-9620-6. PubMed PMID: 25788204; PubMed Central PMCID: PMC4387310.
43. Kamezaki H, Azemoto R, Yokosuka O, Fujimoto T, Obu M, Saito M, Yoshida Y, Koma Y, Maruyama H, Fujimori M. Suspicion of superior mesenteric artery syndrome in a patient with severe gastric dilatation after catheter ablation. Intern Med. 2015;54(6):605-9. doi: 10.2169/internalmedicine.54.3276. PubMed PMID: 25786450.
44. Kanda T, Yokosuka O, Omata M. Faldaprevir for the treatment of hepatitis C. Int J Mol Sci. 2015 Mar 4;16(3):4985-96. doi: 10.3390/ijms16034985. Review. PubMed PMID: 25749475; PubMed Central PMCID: PMC4394460.
45. Jiang X, Kanda T, Nakamoto S, Saito K, Nakamura M, Wu S, Haga Y, Sasaki R, Sakamoto N, Shirasawa H, Okamoto H, Yokosuka O. The JAK2 inhibitor AZD1480 inhibits hepatitis A virus replication in Huh7 cells. Biochem Biophys Res Commun. 2015 Mar 20;458(4):908-12. doi: 10.1016/j.bbrc.2015.02.058. PubMed PMID: 25704089.
46. Kanogawa N, Ogasawara S, Chiba T, Saito T, Motoyama T, Suzuki E, Ooka Y, Tawada A, Kanda T, Mikami S, Azemoto R, Kaiho T, Shinozaki M, Ohtsuka M, Miyazaki M, Yokosuka O. Sustained virologic response achieved after curative treatment of hepatitis C virus-related hepatocellular carcinoma as an independent prognostic factor. J Gastroenterol Hepatol. 2015 Jul;30(7):1197-204. doi: 10.1111/jgh.12925. PubMed PMID: 25682720.
47. Okusaka T, Ueno H, Ikeda M, Mitsunaga S, Ozaka M, Ishii H, Yokosuka O, Ooka Y, Yoshimoto R, Yanagihara Y, Okita K. Phase 1 and pharmacological trial of OPB-31121, a signal transducer and activator of transcription-3 inhibitor, in patients with advanced hepatocellular carcinoma. Hepatol Res. 2015 Dec;45(13):1283-91. doi: 10.1111/hepr.12504. PubMed PMID: 25676869.
48. Maruyama H, Kondo T, Kiyono S, Sekimoto T, Takahashi M, Yokosuka O. Influence of splenorenal shunt on long-term outcomes in cirrhosis. Scand J Gastroenterol. 2015 May;50(5):593-600. doi: 10.3109/00365521.2014.1003401. PubMed PMID: 25635924.
49. Nishikawa T, Tsuyuguchi T, Ishigami H, Sakai Y, Sugiyama H, Nakatani Y, Ohtsuka M, Miyazaki M, Yokosuka O. Peroral cholangioscopy-guided forceps biopsy to evaluate a cicatricial stricture of the biliary duct (with video). Gastrointest Endosc. 2015 Apr;81(4):1030-1; discussion 1031. doi: 10.1016/j.gie.2014.10.008. PubMed PMID: 25597423.
50. Matsumoto A, Yatsuhashi H, Nagaoka S, Suzuki Y, Hosaka T, Tsuge M, Chayama K, Kanda T, Yokosuka O, Nishiguchi S, Saito M, Miyase S, Kang JH, Shinkai N, Tanaka Y, Umemura T, Tanaka E. Factors associated with the effect of interferon-α sequential therapy in order to discontinue nucleoside/nucleotide analog treatment in patients with chronic hepatitis B. Hepatol Res. 2015 Dec;45(12):1195-202. doi: 10.1111/hepr.12488. PubMed PMID: 25594111.
51. Maruoka D, Arai M, Ishigami H, Okimoto K, Saito K, Minemura S, Matsumura T, Nakagawa T, Katsuno T, Yokosuka O. Sporadic nonampullary duodenal adenoma/carcinoma is associated with not only colon adenoma/carcinoma but also gastric cancer: association of location of duodenal lesions with comorbid diseases. Scand J Gastroenterol. 2015 Mar;50(3):333-40. doi: 10.3109/00365521.2014.1003399. PubMed PMID: 25582657.
52. Fujiwara K, Yasui S, Nakano M, Yonemitsu Y, Arai M, Kanda T, Fukuda Y, Oda S, Yokosuka O. Severe and fulminant hepatitis of indeterminate etiology in a Japanese center. Hepatol Res. 2015 Oct;45(10):E141-9. doi: 10.1111/hepr.12483. PubMed PMID: 25582192.
53. Nakamura M, Kanda T, Nakamoto S, Haga Y, Sasaki R, Jiang X, Yasui S, Arai M, Yokosuka O. Reappearance of serum hepatitis B viral DNA in patients with hepatitis B surface antigen seroclearance. Hepatology. 2015 Oct;62(4):1329. doi: 10.1002/hep.27693. PubMed PMID: 25573053.
54. Fujiwara K, Oda S, Abe R, Yokosuka O. On-line hemodiafiltration or high-flow continuous hemodiafiltration is one of the most effective artificial liver support devices for acute liver failure in Japan. J Hepatobiliary Pancreat Sci. 2015 Mar;22(3):246-7. doi: 10.1002/jhbp.204. Review. PubMed PMID: 25565563.
55. Maruyama H, Kondo T, Sekimoto T, Takahashi M, Fujiwara K, Imazeki F, Yokosuka O. Retrograde detection of the intrahepatic portal vein in primary biliary cirrhosis: is sinusoidal blockage the underlying pathophysiology? Eur J Gastroenterol Hepatol. 2015 Mar;27(3):321-7. doi: 10.1097/MEG.0000000000000268. PubMed PMID: 25563140.
56. Tawada A, Chiba T, Ooka Y, Kanogawa N, Saito T, Motoyama T, Ogasawara S, Suzuki E, Kanai F, Yoshikawa M, Yokosuka O. Transarterial chemoembolization with miriplatin plus epirubicin in patients with hepatocellular carcinoma. Anticancer Res. 2015 Jan;35(1):549-54. PubMed PMID: 25550601.
57. Kanda T, Yokosuka O. The androgen receptor as an emerging target in hepatocellular carcinoma. J Hepatocell Carcinoma. 2015 Jun 26;2:91-9. doi: 10.2147/JHC.S48956. Review. PubMed PMID: 27508198; PubMed Central PMCID: PMC4918288.
58. Sekimoto T, Maruyama H, Kondo T, Shimada T, Kiyono S, Yokosuka O. Potential stagnation in the splanchnic hemodynamics demonstrated by the dynamic microbubbles in chronic liver disease. J Gastroenterol Hepatol. 2015 Jun;30(6):1001-8. doi: 10.1111/jgh.12875. PubMed PMID: 25532613.
59. Suzuki E, Ooka Y, Chiba T, Kobayashi K, Kanogawa N, Motoyama T, Saito T, Ogasawara S, Tawada A, Yokosuka O. Incidental tumor necrosis caused by the interventional alteration of hepatic arterial flow in patients with advanced hepatocellular carcinoma. Clin J Gastroenterol. 2015 Feb;8(1):41-6. doi: 10.1007/s12328-014-0542-y. PubMed PMID: 25481841; PubMed Central PMCID: PMC4331596.
60. Ohyama H, Mikata R, Ishihara T, Tsuyuguchi T, Sakai Y, Sugiyama H, Yasui S, Ishii K, Itoh S, Nishikawa T, Watanabe Y, Yokosuka O. Efficacy of stone density on noncontrast computed tomography in predicting the outcome of extracorporeal shock wave lithotripsy for patients with pancreatic stones. Pancreas. 2015 Apr;44(3):422-8. doi: 10.1097/MPA.0000000000000277. PubMed PMID: 25438070.
61. Kawaguchi T, Nagao Y, Abe K, Imazeki F, Honda K, Yamasaki K, Miyanishi K, Taniguchi E, Kakuma T, Kato J, Seike M, Yokosuka O, Ohira H, Sata M. Effects of branched-chain amino acids and zinc-enriched nutrients on prognosticators in HCV-infected patients: a multicenter randomized controlled trial. Mol Med Rep. 2015 Mar;11(3):2159-66. doi: 10.3892/mmr.2014.2943. PubMed PMID: 25394681.
62. Shimada T, Maruyama H, Kondo T, Sekimoto T, Takahashi M, Yokosuka O. Impact of splenic circulation: non-invasive microbubble-based assessment of portal hemodynamics. Eur Radiol. 2015 Mar;25(3):812-20. doi: 10.1007/s00330-014-3476-3. PubMed PMID: 25361826.
63. Fujiwara K, Yasui S, Yonemitsu Y, Arai M, Kanda T, Nakano M, Oda S, Yokosuka O. Fixed point observation of etiology of acute liver failure according to the novel Japanese diagnostic criteria. J Hepatobiliary Pancreat Sci. 2015 Mar;22(3):225-9. doi: 10.1002/jhbp.178. PubMed PMID: 25339364.
64. Fujiwara K, Yasui S, Yonemitsu Y, Arai M, Kanda T, Nakano M, Oda S, Yokosuka O. Importance of the poor prognosis of severe and fulminant hepatitis in the elderly in an era of a highly aging society: Analysis in a Japanese center. Hepatol Res. 2015 Aug;45(8):863-71. doi: 10.1111/hepr.12426. PubMed PMID: 25238570.
65. Maruoka D, Arai M, Tanaka T, Okimoto K, Oyamada A, Minemura S, Tsuboi M, Matsumura T, Nakagawa T, Kanda T, Katsuno T, Imazeki F, Yokosuka O. Mosapride citrate increases postprandial glucagon-like peptide-1, insulin, and gene expression of sweet taste receptors. Dig Dis Sci. 2015 Feb;60(2):345-53. doi: 10.1007/s10620-014-3271-7. PubMed PMID: 25008428.
66. Chiba T, Saito T, Yuki K, Zen Y, Koide S, Kanogawa N, Motoyama T, Ogasawara S, Suzuki E, Ooka Y, Tawada A, Otsuka M, Miyazaki M, Iwama A, Yokosuka O. Histone lysine methyltransferase SUV39H1 is a potent target for epigenetic therapy of hepatocellular carcinoma. Int J Cancer. 2015 Jan 15;136(2):289-98. doi: 10.1002/ijc.28985. PubMed PMID: 24844570.
67. Yasui S, Fujiwara K, Nakamura M, Miyamura T, Yonemitsu Y, Mikata R, Arai M, Kanda T, Imazeki F, Oda S, Yokosuka O. Virological efficacy of combination therapy with corticosteroid and nucleoside analogue for severe acute exacerbation of chronic hepatitis B. J Viral Hepat. 2015 Feb;22(2):94-102. doi: 10.1111/jvh.12258. PubMed PMID: 24750410.
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