DEPARTMENT OF IMMUNOLOGY, GRADUATE SCHOOL OF MEDICINE, CHIBA UNIVERSITY

<Generation and Maintenance of Memory Th1/Th2 cells>

  1. Nakayama, T., and Yamashita, M.: Critical role of the Polycomb and Trithorax complexes in the maintenance of CD4 cell memory. Semin. Immunol. 21:78-83 (2009).
  2. Nakayama, T., and Kimura, Y. M.: Memory Th1/Th2 cell generation controlled by Schnurri-2. Memory T-Cells, edited by Maurizio Zanetti. (2009).
  3. Nakayama, T., and Yamashita, M.: Initiation and maintenance of Th2 cell identity. Truncated title: Regulation of Th2 responses. Curr. Opin. Immunol. 20:265-271 (2008).
  4. Yamashita, M., Kuwahara, M., Suzuki, A., Hirahara, K., Shinnakasu, R., Hosokawa, H., Hasegawa, A., Motohashi, S., Iwama, A., and Nakayama, T.: Bmi1 regulates memory CD4 T cell survival via repression of the Noxa gene. J. Exp. Med. 205:1109-1120 (2008).
  5. Kimura, Y. M., Iwamura, C., Suzuki, A., Miki, T., Hasegawa, A., Sugaya, K., Yamashita, M., Ishii, S., and Nakayama, T.: Schnurri-2 controls memory Th1 and Th2 cell numbers in vivo. J. Immunol. 178:4926-4936 (2007).
  6. Hosokawa, H., Kimura, Y. M., Shinnakasu, R., Suzuki, A., Miki, T., Koseki, H., van Lohuizen, M., Yamashita, M., and Nakayama, T.: Regulation of Th2 cell development by Polycomb group gene bmi-1 through the stabilization of GATA3. J. Immunol. 177:7656-7664 (2006).
  7. Yamashita, M., Hirahara, K., Shinnakasu, R., Hosokawa, H., Norikane, S., Kimura, Y. M., Hasegawa, A., and Nakayama, T.: Crucial role of MLL for the maintenance of memory T helper type 2 cell responses. Immunity 24:611-622 (2006).
  8. Kimura, Y. M., Hosokawa, H., Yamashita, M., Hasegawa, A., Iwamura, C., Watarai, H., Taniguchi, M., Takagi, T., Ishii, S., and Nakayama, T.: Regulation of T helper type 2 cell differentiation by murine Schnurri-2. J. Exp. Med. 201:397-408 (2005).