ページタイトル画像

Cognitive Behavioral Physiology

Overview

Mind and brain are the final frontiers for human beings. Information overload from the internet may cause stress which can affect our brain and mind. To develop more effective treatment and prevention for mental. disorders, we conduct an extensive range of studies about mind and brain, based on the interaction among genes, environments and behaviors from basic molecular researches to clinical intervention trails, using various approaches including biological, medical, psychological and social scientific approaches.

Professor:
Eiji Shimizu, M.D., Ph.D.

TEL: +81-43-226-2027
FAX: +81-43-226-2028
e-mail: neurophysl●ML.chiba-u.jp
URL: http://www.m.chiba-u.ac.jp/class/phys1/

※ Please change "●" mark to at-mark if you send emails.

eiji_shimizu.jpg

Research & Education

fig_phys.jpg

Research of fear extinction using mouse models in learning and memory to understand anxiety and related disorders
We are focusing on understanding molecular mechanisms of fear learning / extinction and development of new treatment approaches for anxiety disorders.

Analyses of human brain functions using functional brain imaging
using magnetic resonance imaging (MRI), near-infrared spectroscopy (NIRS), transcranial direct current stimulation (tDCS) and so on, we study human brain functions including emotions, cognitions and behaviors.

Effectiveness of cognitive behavioral therapy (CBT) for mental disorders
We study clinical effectiveness of CBT for mental disorders including anxiety, depression, eating, developmental and somatic symptoms.

Recent Publications

Yoshinaga N, et al. Cognitive Behavioral Therapy for Patients with Social Anxiety Disorder Who Remain Symptomatic following Antidepressant Treatment: A Randomized, Assessor-Blinded, Controlled Trial. Psychother Psychosom 2016;85:208-217

Sutoh C, et al. Transient contribution of left posterior parietal cortex to cognitive restructuring. Sci Rep. 2015;5:9199

Matsuda S, et al. Sex differences in fear extinction and involvements of extracellular signal-regulated kinase (ERK). Neurobiology of learning and memory 2015. 123. 117-124.

Shimizu E, et al. NMDA receptor-dependent synaptic reinforcement as a crucial process for memory consolidation. Science. 2000 Nov 10; 290: 1170-1174.