Clarification of the effector helper T cells and regulation mechanism of memory differentiation
Description of your research and your dream!
I always keep the following in mind when conducting research: first is deep thinking. Time matters in conducting a study. What is the purpose of the study? What are expected results? If my expectation is right/wrong, what kind of experiment is necessary in the next step? I try to keep asking those questions to myself to prioritize necessary procedures but to omit unnecessary experiments.
Secondly, I try to keep a positive attitude and to be open-minded towards a new experiment and challenge, even when it seems difficult to complete. So I keep my eyes open not only to my research field, but to other areas.
The last but least is the enjoyment of discussion with other researchers. Research is not a solitary pursuit. In fact, all researchers around me are considered good advisers, not enemies, and gradually become trusted colleagues and friends. It is in this way that I would like to continue my research to my heart’s content.
Before coming to Chiba University, I worked within the pharmaceutical industry, RIKEN, and the National Institutes of Health in US. This array of career experiences has contributed to my preferences for how to create a respected research culture and importance of learning from seniors and juniors, as well as supervisors and faculty members. I personally think that “what to study” and “with whom to study” are of equal importance. We welcome you to visit anytime.
- Graduate School of Science and Technology, Tokyo University of Science (Supervisor：Toshinori Nakayama and Takao Arai)
- M.Sc. Graduate School of Science and Technology, Tokyo University of Science (Supervisor：Masato Kubo and Takao Arai)
- D.Sc. Graduate School of Science and Technology, Tokyo University of Science (Supervisor：Toshinori Nakayama and Takao Arai)
- Researcher, Ono Pharmaceutical Co., LTD.
- Researcher, Signal Network, Research Center for Allergy and Immunology, RIKEN (Director: Masato Kubo)
- Visiting fellow, Laboratory of Immunology, NIAID, NIH, USA (Supervisor: William E. Paul)
- Research fellow, Laboratory of Immunology, NIAID, NIH, USA
- Project Associate Professor, Department of Immunology, Graduate School of Medicine, Chiba University
- Yagi, R.*, Zhong, C.*, Northrup, D.L.*, Yu, F., Bouladoux, N., Spencer, S., Hu, G., Barron, L., Sharma, S., Nakayama, T., Belkaid, Y., Zhao, K., and Zhu, J.: The transcription factor GATA3 is critical for the development of all IL-7Rα-expressing innate lymphoid cells. (* Contributed equally) Immunity 40: 378-388 (2014).
- Wei, G.*, Abraham, B.J.*, Yagi, R.*, Jothi, R., Cui, K., Sharma, S., Narlikar, L., Northrup, D.L., Tang, Q., Pau,l W.E., Zhu, J., and Zhao, K.: Genome-wide analyses of transcription factor GATA3-mediated gene regulation in distinct T cell types. (* Contributed equally) Immunity 35: 299-311 (2011).
- Yagi, R., Zhu, J., and Paul, W.E.: An updated view on transcription factor GATA3-mediated regulation of Th1 and Th2 cell differentiation. (Review) Int. Immunol. 23: 415-420 (2011).
- Yagi, R., Junttila, I.S., Wei, G., Urban, J.F. Jr, Zhao, K., Paul, W.E., and Zhu, J.: The transcription factor GATA3 actively represses RUNX3 protein-regulated production of interferon-gamma. Immunity 32: 507-517 (2010).
- The 9th Young Investigator Award, Japanese Society for Immunology
- Paper of the Year Award in Cytokine Biology from HIN-FDA Cytokine Interest Group in 2010
Japanese Society for Immunology