業績・学会活動

2006年以前の業績

  1. Ozawa, K., Hashimoto, K., Kishimoto, T., Ishikura, H., Shimizu, E. and Iyo, M. Immune activation during pregnancy in mice leads to dopaminergic hyperfunction and cognitive impairment in the offspring: a neurodevelopmental animal model of schizophrenia. Biol. Psychiatry. 59(6):546-54.
  2. Shimizu, E., Hashimoto, K., Ohgake, S., Koizumi, H., Okamura, N., Koike, K., Fujisaki, M. and Iyo, M. Association between angiotensin I-converting enzyme insertion/deletion gene functional polymorphism and novelty seeking personality in healthy females. Prog. Neuropsychopharmacol. Biol. Psychiatry. 30(1):99-103.
  3. Iwayama, Y., Hashimoto, K., Nakajima, M., Toyota, T., Yamada, K., Shimizu, E., Itokawa, M., Hoshika, A., Iyo, M. and Yoshikawa, T. Analysis of correlation between serum d-serine levels and functional promoter polymorphisms of GRIN2A and GRIN2B genes. Neurosci. Lett. 394(2):101-4.
  4. Shimizu E, Imai M, Fujisaki M, Shinoda N, Handa S, Nakazato M, Hashimoto K, Iyo M. Maintenance electroconvulsive therapy (ECT) for treatment-resistant disorganized schizophrenia. Prog Neuropsychopharmacol Biol Psychiatry. 2007 in press.
  5. Shimizu E, Watanabe H, Kojima T, Hagiwara H, Fujisaki M, Miyatake R,Hashimoto K, Iyo M. Combined intoxication with methylone and 5-MeO-MIPT. Prog Neuropsychopharmacol Biol Psychiatry. 2006 Jul 27; [Epub ahead of print]
  6. Nakazato M, Hashimoto K, Yoshimura K, Hashimoto T, Shimizu E, Iyo M. No change between the serum brain-derived neurotrophic factor in female patients with anorexia nervosa before and after partial weight recovery. Prog Neuropsychopharmacol Biol Psychiatry. 2006 Aug 30;30(6):1117-21.
  7. Zhang L, Shirayama Y, Shimizu E, Iyo M, Hashimoto K. Protective effects of minocycline on 3,4-methylenedioxymethamphetamine-induced neurotoxicity in serotonergic and dopaminergic neurons of mouse brain. Eur J Pharmacol. 2006 Aug 21;544(1-3):1-9.
  8. Ito T, Sakakibara R, Nakazawa K, Uchiyama T, Yamamoto T, Liu Z, Shimizu E, Hattori T. Effects of electrical stimulation of the raphe area on the micturition reflex in cats. Neuroscience. 2006 Nov 3;142(4):1273-80.
  9. Zhang L, Kitaichi K, Fujimoto Y, Nakayama H, Shimizu E, Iyo M, Hashimoto K. Protective effects of minocycline on behavioral changes and neurotoxicity in mice after administration of methamphetamine. Prog Neuropsychopharmacol Biol Psychiatry. 2006 Dec 30;30(8):1381-93.
  10. 清水栄司. 記憶と学習の分子メカニズムの解明は、高度情報化社会に人類が適応していく方法の答えを出すことができるか 千葉医学雑誌 82(5):255-259.
  11. 清水栄司. パニック障害の薬物療法と精神療法の併用 新しい診断と治療のABC パニック障害 最新医学社 228-236
  1. Shiina A, Nakazato M, Mitsumori M, Koizumi H, Shimizu E, Fujisaki M, Iyo M. An open trial of outpatient group therapy for bulimic disorders: combination program of cognitive behavioral therapy with assertive training and self-esteem enhancement. Psychiatry Clin Neurosci. 2005 Dec;59(6):690-6.
  2. Hashimoto, K., Engberg, G., Shimizu, E., Nordin, C., Lindstrom, L.H. and Iyo, M. (2005) Elevated glutamine/glutamate ratio in cerebrospinal fluid of first episode and drug naive schizophrenic patients. BMC Psychiatry. 5, 6.
  3. Koike, K., Hashimoto, K., Fukami, G., Okamura, N., Zhang, L., Ohgake, S., Koizumi, H., Matsuzawa, D., Kawamura, N., Shimizu, E. and Iyo, M. (2005) The immunophilin ligand FK506 protects against methamphetamine-induced dopaminergic neurotoxicity in mouse striatum. Neuropharmacology 48, 391-397.
  4. Hashimoto, T., Hashimoto, K., Matsuzawa, D., Shimizu, E., Sekine, Y., Inada, T., Ozaki, N., Iwata, N., Harano, M., Komiyama, T., Yamada, M., Sora, I., Ujike, H. and Iyo, M. (2005) A functional glutathione-S-transferase P1 polymorphism is associated with methamphetamine-induced psychosis in Japanese population. Am. J. Med. Genet. 135, 5-9.
  5. Koizumi, H., Hashimoto, K., Shimizu, E., Mashimo, Y., Hata, A. and Iyo, M. (2005) Further analysis of microsatellite in the BDNF gene. Am. J. Med. Genet. 135, 103
  6. Hashimoto, K., Engberg, G., Shimizu, E., Nordin, C., Lindstrom, L.H. and Iyo, M. (2005) Reduced D-serine to total serine ratio in the cerebrospinal fluid of drug naive schizophrenic patients. Prog. Neuropsychopharmacol. Biol. Psychiatry. 29, 767-769.
  7. Koike, K., Hashimoto, K., Takai, N., Shimizu, E., Komatsu, N., Watanabe, H., Nakazato, M., Okamura, N., Stevens, K.E., Freedman, R. and Iyo, M. (2005) Tropisetron improves deficits in auditory P50 suppression in schizophrenia. Schizophr. Res. 76, 67-72.
  8. Ohgake, S., Hashimoto, K., Shimizu, E., Koizumi, H., Okamura, N., Koike, K., Matsuzawa, D., Sekine, Y., Inada, T., Ozaki, N., Iwata, N., Harano, M., Komiyama, T., Yamada, M., Sora, I., Ujike, H., Shirayama, Y. and Iyo, M. (2005) Functional polymorphism of the NQO2 gene is associated with methamphetamine psychosis in Japanese. Addict. Biol. 10, 145-148.
  9. Salama, R., Muramatsu, H., Shimizu, E., Hashimoto, K., Watanabe, H., Komatsu, N., Okamura, N., Koike, K., Shinoda, N., Okada, S., Iyo, M. and Muramastu, T. (2005) Increased midkine levels in sera from patients with Alzheimer's disease. Prog. Neuropharmacol. Biol. Psychiatry. 29, 611-616.
  10. Shimizu, E., Hashimoto, K., Koizumi, H., Kobayashi, K., Itoh, K., Mitsumori, M., Ohgake, S., Okamura, N., Koike, K., Matsuzawa, D., Zhang, L., Kumakiri, C., Nakazato, M., Komatsu, N. and Iyo, M. (2005) No association of the brain-derived neurotrophic factor (BDNF) gene polymorphisms with panic disorder. Prog. Neuropharmacol. Biol. Psychiatry. 29, 708-712.
  11. Kobayashi, K., Shimizu, E., Hashimoto, K., Mitsumori, M., Koike, K., Okamura, N., Koizumi, H., Ohgake, S., Matsuzawa, D., Zhang, L., Nakazato, M., Komatsu, N. and Iyo, M. (2005) Serum brain-derived neurotrophic factor (BDNF) levels in patients with panic disorder: as a biological predictor of response to group cognitive behavioral therapy. Prog. Neuropharmacol. Biol. Psychiatry. 29, 658-663.
  12. Matsuzawa, D., Hashimoto, K., Shimizu, E., Fujisaki, M. and Iyo, M. (2005) Functional Polymorphism of the Glutathione Peroxidase 1 Gene Is Associated with Personality Traits in Healthy Subjects. Neuropsychobiology. 52, 68-70
  13. Hashimoto, K., Shimizu, E., Komatsu, N., Watanabe, H., Shinoda, N., Nakazato, M., Kumakiri, C., Okada, S., Takei, N. and Iyo, M. (2005) No changes in serum epidermal growth factor levels in patients with schizophrenia. Psychiatry. Res. 135, 257-260.
  14. Yamada, K., Ohnishi, T., Hashimoto, K., Ohba, H., Iwayama-Shigeno, Y., Toyoshima, M., Okuno, A., Takao, H., Toyota, T., Minabe, Y., Nakamura, K., Shimizu, E., Itokawa, M., Mori, N., Iyo, M. and Yoshikawa, T. (2005) Identification of multiple serine racemase (SRR) mRNA isoforms and genetic analyses of SRR and DAO in schizophrenia and D-serine levels. Biol. Psychiatry. 57, 1493-1503.
  15. Shimizu, E., Hashimoto, K., Ochi, S., Fukami, G., Fujisaki, M., Koike, K., Okamura, N., Ohgake, S., Koizumi, H., Matsuzawa, D., Zhang, L., Watanabe, H., Nakazato, M., Shinoda, N., Komatsu, N., Morita, F. and Iyo, M. (in press) Posterior cingulate gyrus metabolic changes in chronic schizophrenia with generalized cognitive deficits. J. Psy. Res.
  16. Hashimoto, K., Fujita, Y., Shimizu, E. and Iyo, M. (2005) Phencyclidine-induced cognitive deficits in mice are improved by subsequent subchronic administration of clozapine, but not haloperidol. Eur. J. Pharmacol.. 519, 114-117.
  17. 清水栄司、橋本謙二、伊豫雅臣 (2005) BDNF―抗うつ薬の効果発現機序を含めてー. カレントテラピー 23(1)86.
  18. 清水栄司 (2005) 地下鉄に乗るのがこわい. クリニックQ&A 532、12-13.
  19. 小林圭介、清水栄司、三森真実、伊豫雅臣、(2005) 認知行動療法の実際「パニック障害」. こころの科学121、62-68.
  20. 清水栄司、今井逸雄、藤崎美久、篠田直之、半田聡、中里道子、渡邊博幸、米澤洋介、木村章、橋本謙二、伊豫雅臣: (2005) clozapineが無効であったため、ECTへ切り替えた薬物治療抵抗性の慢性解体型統合失調症の1例. 臨床精神薬理 8,2057-2059.
  21. 井貫正彦、中里道子、野々村司、熊切力、西澤馨、清水栄司、伊豫雅臣:(2005) Clozapineのtherapeutic window (有効血中濃度域)の存在が示された治療抵抗性統合失調症の1例. 臨床精神薬理 8,2060-2065.
  22. 原口正、渡邉博幸、浅香琢也、橋本佐、佐藤康一、清水栄司、小松尚也、伊豫雅臣 (2005) Clozapineにより無顆粒球症を呈し、G-CSF製剤により回復した1例. 臨床精神薬理 8,2066-2070.
  1. Itoh, K., Hashimoto, K., Kumakiri, C., Shimizu, E. and Iyo, M. (2004) Association between brain-derived neurotrophic factor 196 A/G polymorphism and personality traits in healthy subjects. Am. J. Med. Genet. 124B, :61-63.
  2. Shimizu, E., Hashimoto, K. and Iyo, M. (2004) Ethinic differences of the BDNF 196G/A (val66met) polymorphism frequencies: the possibility to explain ethnic mental traits. Am. J. Med. Genet. 126B, 122-123.
  3. Okamura, N., Hashimoto, K., Shimizu, E., Kumakiri, C., Komatsu, N. and Iyo, M. (2004) Adenosine A1 receptor agonists block the neuropathological changes in rat retrosplenial cortex after administration of the NMDA receptor antagonist dizocilpine. Neuropsychopharmacol. 29, 544-550.
  4. Koizumi, H., Hashimoto, K., Kumakiri, C., Shimizu, E., Sekine, Y., Ozaki, N., Inada, T., Harano, M., Komiyama, T., Yamada, M., Sora, I., Ujike, H., Takei, N. and Iyo, M. (2004) Association between the glutathione S-transferase M1 gene deletion and female methamphetamine abusers. Am. J. Med. Genet. 126B, 43-45.
  5. Hashimoto, K., Fukushima, T., Shimizu, E., Okada, S., Komatsu, N., Okamura, N., Koike K, Koizumi, H., Kumakiri, C., Imai, K. and Iyo, M. (2004) Possible role of D-serine in the pathophysiology of Alzheimer's disease. Prog. Neuropharmacol. Biol. Psychiatry. 28, 385-388.
  6. Koike, K., Hashimoto, K., Okamura, N., Ohgake, S., Shimizu, E., Koizumi, H., Komatsu, N. and Iyo, M. (2004) Decrease of cell proliferation in the dentate gyrus of hippocampus of alpha-7 nicotinic receptor heterozygous mice. Prog. Neuropharmacol. Biol. Psychiatry. 28, 517-520.
  7. Koizumi, H., Hashimoto, K., Itoh, K., Nakazato, M., Shimizu, E., Ohgake, S., Koike, K., Okamura, N., Matsushita, S., Suzuki, K., Murayama, M., Higuchi, S. and Iyo, M. (2004) Association between the brain-derived neurotrophic factor 196G/A polymorphism and eating disorders. Am. J. Med. Genet. 127B, 125-127.
  8. Shimizu, E., Hashimoto, K., Kobayashi, K., Mitsumori, M., Ohgake, S., Koizumi, H., Okamura, N., Koike, K., Kumakiri, C., Nakazato, M., Komatsu, N. and Iyo, M. (2004) Lack of association between angiotensin I-converting enzyme (ACE) insertion (I)/deletion (D) gene functional polymorphism and panic disorder. Neurosci. Lett. 363, 81-83.
  9. Fukami, G., Hashimoto, K., Koike, K., Okamura, N., Shimizu, E. and Iyo, M. (2004) Effect of antioxidant N-acetyl-L-cysteine on behavioral changes and neurotoxicity in rats after administration of methamphetamine. Brain Res. 1016, 90-95.
  10. Hashimoto, K., Tsukada, H., Nishiyama, S., Fukumoto, D., Kakiuchi, T., Shimizu, E. and Iyo, M. (2004) Protective effects of N-acetyl-L-cysteine on the reduction of dopamine transporters in striatum of monkeys treated with methamphetamine. Neuropsychopharmacology 29, 2018-2023.
  11. Nakazato, M., Hashimoto, K., Shiina, A., Koizumi, H., Mitsumori, M., Imai, M., Shimizu, E. and Iyo, M. (2004) No changes in serum ghrelin levels in female patients with bulimia nervosa. Prog. Neuropharmacol. Biol. Psychiatry. 28, 1181-1184.
  12. Hashimoto, K., Tsukada, H., Nishiyama, S., Fukumoto, D., Kakiuchi, T., Shimizu, E. and Iyo, M. (2004) Protective effects of N-acetyl-L-cysteine on the reduction of dopamine transporters in striatum of monkeys treated with methamphetamine. New York Academy of Sciences, New York, Vol. 1025, 231-235.
  13. 藤崎美久、清水栄司、橋本謙二、伊豫雅臣 (2004) 恐怖条件付けにおける扁桃体海馬移行領域の役割. 生体の科学 55(6) 590-597
  14. 清水栄司、橋本謙二、伊豫雅臣(2004)うつ病とBDNF(brain-derived neurotrophic factor) 日本神経精神薬理学雑誌 24(3):147-50.
  15. 清水栄司, 小林圭介, 三森真実, 伊豫雅臣 (2004)パニック障害の認知行動療法とその有効性. パニック障害セミナー2004. 越野好文・貝谷久宣編、日本評論社. 東京.53-63.
  1. Hashimoto, K., Fukushima, T., Shimizu, E., Komatsu, N., Watanabe, H., Shinoda, N., Nakazato, M., Kumakiri, C., Okada, S., Hasegawa, H., Imai, K. and Iyo, M. (2003) Decreased levels of D-serine in the serum of patients with schizophrenia: Evidence in support of the NMDA receptor hypofunction hypothesis of schizophrenia. Arch. Gen. Psychiatry. 60: 572-576.
  2. Nakazato, M., Hashimoto, K., Shimizu, E., Kumakiri, C., Koizumi, H., Okamura, N., Mitsumori, M., Komatsu, N. and Iyo, M. (2003) Decreased Levels of Serum Brain-Derived Neurotrophic Factor in Female Patients with Eating Disorders. Biol. Psychiatry; 54(4):485-90
  3. Shimizu, E., Hashimoto, K., Okamura, N., Koike, K., Komatsu, N., Kumakiri, C., Nakazato, M., Watanabe, H., Shinoda, N., Okada, S. and Iyo, M. (2003) Alterations of Serum Levels of Brain-Derived Neurotrophic Factor (BDNF) in Depressed Patients without or with Antidepressants. Biol. Psychiatry 54(1):70-5
  4. Okamura, N., Hashimoto, K., Kanahara N, Shimizu, E., Kumakiri, C., Komatsu, N. and Iyo, M. (2003) Protective effect of antipsychotic drug zotepine on dizocilpine-induced neuropathological changes in rat retrosplenial cortex. Eur. J. Pharmacol. 461, 93-98.
  5. Shimizu, E., Wang, H., Tang, Y.P., Cho, M., Kyin, M., Zuo, W., Robinson, D.A., Alaimo, P.J., Zhang, C., Morimoto, H., Zhuo, M., Feng, R., Shokat, K.M. and Tsien, J.Z. (2003) Inducible protein knockout reveals temporal requirement of CaMKII reactivation for memory consolidation in the brain. Proc Natl Acad Sci U S A 100, 4287-4292.
  6. Shimizu, E., Hashimoto, K., Salama, R.H.M., Watanabe, H., Komatsu, N., Okamura, N., Koike, K., Shinoda, N., Nakazato, M., Kumakiri, C., Okada, S., Muramatsu, H., Muramatsu, T. and Iyo, M. (2003) Two clusters of serum midkine levles in drug-naive patients with schizophrenia. Neurosci. Lett. 344: 95-98.
  7. Okamoto, H., Shino, Y., Hashimoto, K., Kumakiri, C., Shimizu, E., Shirasawa, H. and Iyo, M. (2003) Dynamic changes of AP-1 transcription factor DNA binding activity in rat brain after administration of antidepressant amitriptyline and brain-derived neurotrophic factor. Neuropharmacol 45(2):251-259.
  8. Toyooka, K., Watanabe, Y., Iritani, S., Shimizu, E., Iyo, M., Nakamura, R., Asama, K., Makifuchi, T., Kakita, A., Takahashi, H., Someya, T. and Nawa, H. (2003) A decrease in interleukin-1 receptor antagonist expression in the prefrontal cortex of schizophrenic patients. Neurosci. Res. 46, 299-307.
  9. Hashimoto, K., Shimizu, E., Komatsu, N., Nakazato, M., Okamura, N., Watanabe, H., Kumakiri, C., Shinoda, N., Okada, S., Takei, N. and Iyo, M. (2003) Increased levels of serum basic fibroblast growth factor in Schizophrenia. Psychiatry. Res.;120, 211-8
  10. Shimizu, E., Hashimoto, K., Watanabe, H., Komatsu, N., Okamura, N., Koike, K., Shinoda, N., Nakazato, M., Kumakiri, C., Okada, S. and Iyo, M. (2003) Serum brain-derived neurotrophic factor (BDNF) levels in schizophrenia are indistinguishable from controls. Neurosci. Lett. 351, 111-4.
  11. Okamura, N., Hashimoto, K., Shimizu, E., Koike, K., Ohgake, S., Koizumi, H., Kumakiri, C., Komatsu, N. and Iyo, M. (2003) Protective effect of LY329268, a selective group II metabotropic glutamate receptor agonist, on dizocilpine-induced neuropathological changes in rat retrosplenial cortex. Brain Res. 992, 114-119.
  12. 清水栄司, 伊豫雅臣(2003)第13章、依存性薬物の薬理、臨床精神薬理ハンドブック(樋口輝彦・小山司・神庭重信編)、医学書院.東京. 267-277.
  1. Shimizu, E., Hashimoto, K., Komatsu, N. and Iyo, M. (2002) Roles of endogenous glutathione levels on 6-hydroxydopamine-induced apoptotic neuronal cell death in human neuroblastoma SK-N-SH cells. Neuropharmacology 43,434-443.
  2. 2.Nishimura Y , Nakajima Y. . Effect of muscle length on the recruitment property of single motor units in humans.. Neuroscience Letters 2002; 332:49-52
  3. 3.Sakakibara R , Nakazawa K, Uchiyama T, Yoshiyama M, Yamanishi T, Hattori T. .Micturition-related electrophysiological properties in the substantia nigra pars compacta and the ventral tegmental area in cats.. xAutonomic Neuroscience:Basic&Clinical 2002; 102:30 -38
  4. Sakakibara R , Nakazawa K, Shiba K, Nakajima Y, Uchiyama T, Yoshiyama M, Yamanishi T, Hattori T. .Firing patterns of micturition-related neurons in the pontine storage centre in cats.. Autonomic Neuroscience:Basic&Clinical 2002; 99:24-30
  5. 宮崎総一郎 , 西村幸男、柴啓介. スポーツと感覚・機能 スポーツと呼吸・発声. ENTONI 2002; 19:6- 10
  6. 下山一郎 , 中島祥夫、笠置泰史、ロペス・アレックス . 独立成分分析- 双極子解析への応用とその限界. 臨床脳波 2002; 44:637- 641
  7. 伊豫雅臣、清水栄司、尾崎茂 (2002) 薬物依存の疫学と中枢機構.Clinical Neuroscience 20,571-574
  8. 清水栄司、橋本謙二、伊豫雅臣(2002)強迫性障害の神経生物学的研究―最近の動向―.日本神経精神薬理学雑誌 22,111-119.
  1. Mody, M., Cao, Y., Cui, Z., Tay, K.Y., Shyong, A., Shimizu, E., Pham, K., Schultz, P., Welsh, D. and Tsien, J.Z. (2001) Genome-wide gene expression profiles of the developing mouse hippocampus. Proc. Natl. Acad. Sci. USA 98,8862-8867.
  2. Abla D , Nakajima Y, Shimoyama I . . Cerebral Functional localization of word recognition process during silent reading of native and non-native languages : a study of event-related potentials.. 千葉医学 2001;77:347-357
  3. 笠置泰史 , 下山一郎、中島祥夫 . シュミレーションによる脳電図深度成分分離の試み. 臨床神経生理学 2001; 29:125- 126
  1. Shimizu, E., Tang, Y.P., Rampon, C. and Tsien, J.Z. (2000) NMDA receptor-dependent synaptic reinforcement as a crucial process for memory consolidation. Science 290,1170-1174.
  2. Bishop, A.C., Ubersa, J.A., Petsch, D.T., Matheos, D.P., Gray, N.S., Blethrow, J., Shimizu, E., Tsien, J.Z., Schultz, P.G., Rose, M.D., Wood, J.L., Morgan, D.O. and Shokat, K.M. (2000) A chemical switch for inhibitor-sensitive alleles of any protein kinase. Nature 407,395-401.
  3. Rampon, C., Tang, Y.P., Goodhouse, J., Shimizu, E., Kyin, M. and Tsien, J.Z. (2000) Enrichment induces structural changes and recovery from nonspatial memory deficits in CA1 NMDAR1-knockout mice. Nat. Neurosci. 3,238-244.
  4. Yasuno, I., Kodama, K., Kumakiri, K., Shimizu, E. and Sato, T. (2000) Screening for point mutations of the RYR1 and SCN4AA genes in neuroleptic malignant syndrome. Chiba Igaku 76,75-79.
  5. Nagumo K , Hirayama K, Nakajima Y, Takahashi M . . Crossed linguo-buccal reflex in post-stroke patients.. Journal of the Neurological Sciences 2000;182 :51-56
  6. Shimoyama I , Kasagi Y, Kaiho T, Shibata T, Nakajima Y, Asano H . . Flash-related synchronization and desynchronization revealed by a multiple band frequency analysis.. The Japanese Journal of Physiology 2000; 50:553- 559
  7. Mizobuchi K , Kuwabara S, Toma S, Nakajima Y, Ogawara K, Hattori T . . Single unit responses of human cutaneousx mechanoreceptors to air-puff stimulation.. Clinical Neurophysiology 2000; 111:1577- 1581
  8. Takahashi Y , Hirayama J, Nakajima Y, Ohtori S, Takahashi K. . Electrical stimulation of the rat lumbar spine induces reflex action potentials in the nerves to the lower abdomen.. SPINE 2000; 25:411- 417
  9. Kuwabara S ,Mizobuchi K, Toma S, Nakajima Y, Ogawara K, Hattori T . . "Tactile"sensory nerve potentials elicited by air-puff stimulation: A microneurographic study.. EUROLOGY 2000; 54:762- 765
  10. Kaiho T , Shimoyama I, Nakajima Y, Ochiai T . . Gastric and non-gastric signals in electrogastrography..Journal of the Autonomic Nervous System 2000; 79:60- 66
  11. Mine S , Iwasa H, Nakajima Y, Yamaura A . . Dipole source localization of interictal epileptiform activity in temporal lobe epilepsy with medial temporal lesion.. Psychiatry and Clinical Neurosciences 2000; 54:23- 29
  12. Kobayashi N , Shiba K, Nakazawa K, Satoh I, Nakajima Y, Konno A . Sound-induced laryngeal and respiratory reflexes originate from vestibular afferents. NeuroReport 2000; 11: 207- 209
  13. Yasuda K , Kobayashi K, Sugita K, Takanashi J, Kohno Y, Iwasa H, Mine S, Nakajima Y. . Estimation of photoparoxysmal response elicited by half-field visual stimulation. NeuroReport 2000; 11: 203- 206
  14. 柴田忠彦 , 岩佐博人、下山一郎、佐藤甫夫、中島祥夫 . 視覚刺激後に出現する脳波γ帯域波の生理学的意義に関する研究:GO/NOGO 課題を用いて. 臨床脳波 2000; 42: 94- 98
  15. 柴田忠彦 , 岩佐博人、峯 清一郎、保田貴美子、中島祥夫 .  焦点性 徐波複合の発見に関与する生理学的基盤に関する研究 -3層モデル双極子追跡法による徐波成分の解析を中心に-. てんかん治療研究振興財団研究年報 2000;12:119- 124
  16. 柴田忠彦 , 下山一郎、 岩佐博人、 中島祥夫 . GO/NOGO課題実行中の脳波γ帯域パワーの経時変化. 臨床脳波/別冊 2000; 42:555- 560
  1. Tang, Y.P., Shimizu, E., Dube, G.R., Rampon, C., Kerchner, G.A., Zhuo, M., Liu, G. and Tsien, J.Z. (1999) Genetic enhancement of learning and memory in mice. Nature 401,63-69.
  2. Liu, Y., Bishop, A., Witucki, L., Kraybill, B., Shimizu, E., Tsien, J.Z., Ubersa, J., Blethrow, J., Morgan, D.O. and Shokat, K.M. (1999) Structural basis for selective inhibition of Src family kinases by PP1. Chem. Biol. 6,671-678.
  3. Kumakiri, C., Kodama, K., Shimizu, E., Yamanouchi, N., Okada, S., Noda, S., Okamoto, H., Sato, T. and Shirasawa, H. (1999) Study of the association between the serotonin transporter gene regulatory region polymorphism and personality traits in a Japanese population. Neurosci. Lett. 263,205-207.
  4. Shimoyama I , Asano F, Kasagi Y, Kaiho T, Nakajima Y . . New algorithm for high resolution spectral analysis.. JOURNAL OF BRAIN SCIENCE 1999;25:147- 151
  5. Kuwabara S , Nakajima Y, Hattori T, Toma S, Mizobuchi K, Ogawara K . Activity-dependent excitability changes in chronic inflammatory demyelinating polyneuropathy: A microneurographic study. . Muscle Nerve 1999; 27: 899- 904
  6. Kuwabara S , Nakajima Y, Hattori T, Toma S, Mizobuchi K, Ogawara K. . Activity-dependent excitability changes in chronic inflamatory demyelinating polyneuropathy: a microneurographic study.. Muscle Nerve 1999; 22: 899- 904
  7. Nakazawa K. , Umezaki T, Zheng Y, Miller AD. . Behaviors of bulbar respiratory interneurons during fictive swallowing and vomitting.. Otolaryngol Head Neck 1999; 120: 412- 418
  8. Shiba K , Satoh I, Kobayashi N, Hayashi F. . Multifunctional laryngeal motoneurons: an intracellular study in the cat.. J Neurosci 1999; 19: 2717-2727
  9. Shiba K. , Miura T, Yuza J, Sakamoto T, Nakajima Y. . Laryngeal afferent inputs during vocalization in the cat.. NeuroReport 1999; 10: 987- 991
  10. Shibata T , Shimoyama I, Ito T, Abla D, Iwasa H, Koseki K, Yamanouchi N, Sato T, Nakajima Y. . Attention changes the peak latency of the visual gamma-band oscillation of the EEG.. NeuroReport 1999; 10: 1167- 1170
  11. Shibata T , Shimoyama I, Ito T, Abla D, Iwasa H, Koseki K, Yamanouchi T, Sato T, Nakajima Y. . Event-related dynamics of the gamma-band oscillation in the human brain: information processing during a GO/NOGO hand movement task.. Neurosci Res 1999; 33: 215- 222
  12. Takahashi Y , Murata A, Nakajima Y. . Dilatation of subcutaneous perforating blood vessels associated with capsaicin-induced cutaneous axon reflex: demonstration with subtraction thermography.. J Autonom Nerv Syst 1999; 75: 87- 92
  13. Shimoyama I , Nakajima Y, Shibata T, Ito T, Abla D, Kansaku K, Mizota J . . Binocular interactions in visual evoked cortical potentials with two light-emitting-diodes.. Documenta Ophthalmologica 1999; 97:1- 7
  14. Takahashi Y . . Principles in the arrangement of dermatomes and revaluation of dermatome charts.. 千葉医学1999; 75:209- 213
  15. 中島祥夫 , . 体性感覚と内蔵感覚. (堀 清記) 生理学TEXT. 東京: 南山堂. 1999: 444- 463
  16. 当間 忍 , . 5.6 神経内科疾患に伴う睡眠障害:頭痛. (太田龍朗、大川 匡子、塩澤全司) 臨床睡眠医学. 東京: 朝倉書店. 1999: 315- 320
  17. 峯 清一郎 , 平井伸治、山上岩男、小野純一、山浦 晶、中島祥夫 . 感覚運動野近傍脳動静脈奇形における第1次体性感覚野の局在双極子追跡法による検討-. 脳神経 1999; 51: 331- 337
  18. 竹内綱吉, . 疼痛性皮膚電気刺激時の筋および皮膚交感神経活動の変化 . 千葉医学1999; 70: 239- 244
  19. 佐藤勇, . 除脳ネコくしゃみと咳の神経機構 . 脳波と筋電図 1999; 27:120-121
  20. 唐亜平、清水栄司、Claire Rampon、Joe Z. Tsien (1999) 学習・記憶の遺伝的増強マウス(NMDA受容体2B型への着目). 実験医学17,2565-2568.
  1. Homma S. , Nakajima Y, Toma S, Ito T, Shibata T. . Intracerebral source localization of mental process-related potentials elicited prior to mental sweating response.. Neurosci Lett 1998; 247: 25- 28
  2. Ito T , Shimoyama I, Shibata T, Iwasa H, Koseki K, Sato T, Nakajima Y. . ERPs to semantic and syntactic errors using verb and particle incongruities.. (Koga Y, Nagata K, Hirata K.) Brain Topography Today. Amsterdam: Elsevier. 1998: 225- 228
  3. Kansaku K. , Shimoyama I, Nakajima Y, Higuchi Y, Nakazaki S, Kubota M, Morita F, Kusaka T, Katoh K, Yamaura A. . Functional magnetic resonance imaging during recognition of written words: Chinese characters for concrete objects versus abstract concepts.. Neurosci Res 1998; 30: 83-86
  4. Miller AD. , Umezaki T, Nakazawa K, Shiba K, Siniaia MS, Zheng Y. . Recovery of retching after lesions involving the nucleus of the solitary tract.. Neurosci Res 1998; 31: 77- 88
  5. Mine S , Oka N, Yamaura A, Nakajima Y . Presurgical functional localization of primary somatosensory cortex by dipole tracing method of scalp-skull-brain model applied to somatosensory evoked potential. Electroencephalogr Clin Neurophysiol 1998; 108: 226- 233
  6. Mine S. , Yamaura A, Iwasa H, Nakajima Y, Shibata T, Itoh T. . Dipole source localization of ictal epileptiform activity.. Neuroreport 1998; 9: 4007-4013
  7. Nakazato T. , Shikama T, Toma S, Nakajima Y, Masuda Y. . Nocturnal variation in human sympathetic baroreflex sensitivity.. J Autonom Nerv Syst 1998; 70: 32- 37
  8. Satoh I , Shiba K, Kobayashi N, Nakajima Y, Konno A. . Upper airway motor outputs during sneezing and coughing in decerebrate cats.. Neurosci Res 1998; 32: 131- 135
  9. Shibata T , Shimoyama I, Ito T, Abla D, Iwasa H, Koseki K, Yamanouchi N, Sato T, Nakajima Y. . The time course of inter- and intrahemispheric EEG coherence during a go/no-go task in humans.. (Hashimoto I, Kakigi R.) Recent Advances in Human Neurophysiology. Amsterdam: Elsevier. 1998: 1063- 1067
  10. Shibata T. , Shimoyama I, Ito T, Abla D, Iwasa H, Koseki K, Yamanouchi N, Sato T, Nakajima Y. . The synchronization between brain areas under motor inhibition process in humans estimated by the event-related coherence.. Neurosci Res 1998; 31: 265- 271
  11. Shimoyama I , Nakajima Y, Shibata T, Ito T, Abla D. . Positive afterimage for cortical evoked potentials. J Brain Sci 1998; 24: 83- 87
  12. Shimoyama I , Nakajima Y, Shibata T, Ito T, Kansaku K. . Differences in auditory scalp potentials evoked by meaningful words and nonlinguistic stimuli.. Perceptual and Motor Skills 1998; 86: 464- 466
  13. Shimoyama I , Nakajima Y, Ito T, Shibata T, Abla D. . Visual evoked potentials in word-recognition: Chinese characters vs. English words.. (Koga Y, Nagata K, Hirata K.) Brain Topography Today. Amsterdam: Elsevier. 1998: 229- 232
  14. Shimoyama I , Nakajima Y, Shibata T, Ito T, Abla D, Okamoto Y. . Normalized wave energy for background activity in visual evoked potentials. JBrain Sci 1998; 24 : 13- 17
  15. Shimoyama I , Ito T, Shibata  T, Abla D, Nakajima Y. . Hemispheric laterality in contexual recognition.. Jpn J Physiol 1998; 48: 493- 497
  16. Umezaki T , Nakazawa K, Miller AD. . Behaviors of hypoglossal hyoid motoneurons in laryngeal and vestibular reflexes and in deglutition and emesis.. Am J Physiol 1998; 274: R950- R955
  17. Umezaki T. , Shiba K, Zheng Y, Miller AD. . Upper airway motor output during vomiting versus swallowing in the decerebrate cat.. Brain Res 1998; 781: 25- 36
  18. Yasuda K. , Takanashi J, Sugita K, Niimi H, Iwasa H, Nakajima Y. . Estimation of electric focus of photoparoxysmal dischare by dipole tracing method.. (Koga Y, Nagata K, Hirata K.) Brain Topography Today. Amsterdam: Elsevier. 1998: 491- 494
  19. 岩佐博人 , 古関啓二郎、柴田忠彦、伊藤寿彦、峯清一郎、佐藤甫夫、中島祥夫 . 双極子追跡法(Dipole Tracing) -てんかん性棘波の脳内電源推定への応用-. (清野昌一) 精神医学レビュー No.10「難治てんかん」. 東京: ライフ・サイエンス. 1998: 89- 93
  20. 古関啓二郎 , 岩佐博人、柴田忠彦、伊藤寿彦、中島祥夫、佐藤甫夫 . 三層モデル双極子追跡法によるてんかん性笑い発作の脳内電源の推定. 臨床脳波 1998; 40: 577- 582
  21. 柴田忠彦 , 岩佐博人、古関啓二郎、伊藤寿彦、佐藤甫夫、中島祥夫 . 長期間にわたり偽発作として治療されてきた前頭葉てんかんと考えられた一例. 精神科治療学 1998; 13 (4): 467- 472
  22. 沼田憲治 , 中島祥夫、清水 忍 . 図形認知の右大脳半球優位性ー半側視野図形呈示を用いた事象関連電位による研究ー. 理学療法学1998; 25 (1): 1- 5
  23. 保田貴美子 , 高梨潤一、杉田克生、新美仁男、岩佐博人、中島祥夫 . 光過敏性てんかんにおける外側膝状体の関与ー双極子追跡法による検討ー. 脳と発達 1998; 30: 377- 382
  1. Shimizu, E., Shirasawa, H., Kodama, K., Kuroyanagi, H., Shirasawa, T., Sato, T. and Simizu, B. (1997) Glutamate dehydrogenase mRNA is immediately induced after phencyclidine treatment in the rat brain. Schizophr. Res. 25,251-258.
  2. Nakazawa K , Zheng Y, Umezaki T, Miller AD . Vestibular inputs to bulbar respiratory interneurons in the cat.. NeuroReport 1997; 8: 3395- 3398
  3. Nakazawa K , Shiba K, Satoh I, Yoshida K, Nakajima Y, Konno A . Role of pulmonary afferent inputs in vocal on-switch in the cat.. Neurosci Res 1997; 29: 49- 54
  4. Shiba K , Yoshida K, Nakajima Y, Konno A . Influences of laryngeal afferent inputs on intralaryngeal muscle activity during vocalization in the cat.. Neurosci Res 1997; 27: 85- 92
  5. Shiba K , Umezaki T, Zheng Y, Miller AD . The nucleus retroambigualis controls laryngeal muscle activity during vocalization in the cat.. Exp Brain Res 1997; 115: 513- 519
  6. Shibata T , Shimoyama I, Ito T, Abla D, Iwasa H, Koseki K, Yamanouchi N, Sato T, Nakajima Y. . The time course of interhemispheric EEG coherence during GO/NO-GO task in humans.. Neurosci Lett 1997; 233: 117- 120
  7. Shimoyama I , Nakajima Y, Shibata T, Ito T. . Visual evoked potentials relating to recognizing visual motion.. J Brain Sci 1997; 23: 127- 133
  8. Shimoyama I , Nakajima Y, Ito T, Shibata T. Visual evoked potentials relating to imagery: words for concrete objects versus absolute concepts.. Brain Topogr 1997; (9): 271- 274
  9. Shimoyama I , Nakajima Y, Ito T, Shibata T, Sato I, Abla D. . Comparison between visual evoked potentials with a light-emitting-diode and a stroboscope, analyzed with singular value decomposition.. J Brain Sci 1997; 23: 115- 120
  10. Shimoyama I , Nakajima Y, Ito T, Shibata T, Abla D. . Flash-visual evoked potentials with principal component analysis.. J Brain Sci 1997; 23: 101-106
  11. Shimoyama I , Nakajima Y, Shibata T, Ito T, Okomoto Y. . Singular value decomposition for visual evoked potentials.. J Brain Sci 1997; 23: 107-113
  12. Shimoyama I , Nakajima Y, Shibata T, Ito T, Abla D, Kansaku K. . Human sclap evoked potentials using simultaneous stimuli with flashes and tones.. J Brain Sci 1997; 23: 121- 126
  13. Yoshida K , Nakazawa K, Konno A, Nakajima Y. Does nitric oxide mediate plasma extravasation induced by electrical stimulation of the superior salivatory nucleus in cat nasal mucosa?. Neurosci Res 1997; 27: 281- 284
  14. Zheng Y , Umezaki T, Nakazawa K, Miller AD . Role of pre-inspiratory neurons in vestibular and laryngeal reflexes and swallowing and vomiting.. Neurosci Lett 1997; 225: 161- 164
  15. 伊藤寿彦 , 岩佐博人、柴田忠彦、古関啓二郎、佐藤甫夫、中島祥夫 . 双極子追跡法による前頭葉てんかんの脳内電源推定. てんかん研究 1997; (15): 7- 16
  16. 柴田忠彦 , 伊藤寿彦、岩佐博人、佐藤甫夫、中島祥夫 . SSB/DT法による焦点性棘徐波複合の脳内電源の推定ー徐波成分に関する分析を中心にー. 脳波と筋電図 1997; 25: 249- 259
  17. 沼田憲治 , 中島祥夫、村田 淳、清水 忍 . 半側視野刺激におけるN160成分の検討. 脳波と筋電図 1997; 25: 321- 327
  18. 石井光子 , 杉田克生、中島祥夫、新美仁男 . 三層(頭皮、頭蓋骨、脳組織)頭部モデル双極子追跡法による光突発反応の発現に関与する脳内電源推定の試み. てんかん研究 1997; 15: 172- 177
  19. 中島祥夫 , 本間三郎 . 第IV章 双極子追跡法の評価:硬膜下電極通流による電源の推定. (本間三郎) 脳内電位発生源の特定: 脳波双極子追跡法. 東京: 日本評論社. 1997: 77- 81
  20. 中島祥夫 , 下山一郎 . 第VI章 A. VEPの解析:文字認識. (本間三郎) 脳内電位発生源の特定:脳波双極子追跡. 東京: 日本評論社. 1997: 113- 115
  21. 中島祥夫 , . 知情意の脳活動ー脳波の双極子追跡法による解析を中心にー. 生体の科学 1997; 48: 25- 30
  22. 当間 忍 , 中島祥夫 . マイクロニューログラフィによる単一または複合神経活動電位伝導速度の測定 現代臨床機能検査ーその実際と解釈. 日本臨床 1997; 55: 420- 425
  23. 当間 忍 , 中島祥夫 . 微小神経活動電位の最近の進歩ー交感神経活動電位を中心にー. 骨・関節・靭帯 1997; 10: 629- 633
  1. Shimizu, E., Shirasawa, H., Kodama, K., Sato, T. and Simizu, B. (1996) Expression, regulation and polymorphism of the mxi1 genes. Gene 176,45-48.
  2. Nakajima Y , Homma S. . Estimation of generator sources with dipole tracing method based on SSB (scalp-skull-brain) head model: A survey of theresearch and clinical application in Japan.. (Kimura J & Shibasaki H.) Recent Advance in Clinical Neurophysiology.. Amsterdam: Elsevier. 1996: 978-982
  3. Shiba K , Umezaki T, Zheng Y, Miller AD. . Fictive vocalization in the cat.. Neuroreport 1996; 7: 2139- 2142
  4. Shiba K , Siniaia MS, Miller AD . Role of ventral respiratory group bullbospinal expiratory neurons in vestibular-respiratory reflexes.. J Neurophysiol 1996; 76: 2271- 2279
  5. Shimoyama I , Uemura K, Morita Y, Miyanaga F, Kuroda R, Nakamura T. . Visual evoked potentials to a faint light: signal propagation analyzed with peak latency and topographic mapping.. Brain Topogr 1996; 8: 245- 247
  6. Shimoyama I , Nakajima Y . Statistical analysis for visual evoked potentials with a light emitting diode: considering the background activity.. J Brain Sci 1996; 22: 61- 65
  7. Shimoyama I , Miyanaga F, Nishizawa S, Uemura K, Morita Y. . Statistical analysis of short-latency flash visual evoked cortical potentials with noncephalic reference.. Doc Ophthalmol 1996; 91: 363- 370
  8. Shimoyama I , Nakajima Y . Human slow brain potentials related to volume of auditory.. J Brain sci 1996; 22: 25- 28
  9. Takahashi Y , Nakajima Y . Dermatomes in the rat limbs as determined by antidromic stimulation of sensory C-fibers in spinal nerves.. Pain 1996; 67: 197- 202
  10. Takahashi Y , Morinaga T, Nakamura S, Suseki K, Takahashi K, Nakajima Y. . Neural connection between the ventral portion of the lumbar intervertebral disc and the groin skin.. J Neurosurg 1996; 85: 323- 328
  11. Yoshida K , Shiba K, Nakazawa K, Konno A, Nakajima Y. . Increased nasal mucosal blood flow, airway resistance and secretion nduced by electrical stimulation of the superior salivatory nucleus in cats.. Neurosci Res 1996; 25: 371- 377
  12. 中島祥夫 , . 第12章 運動機能の脊髄機構(分担訳). (坂東武彦、小山省三) バーン・レヴィ生理学. 新潟: 西村書店. 1996: 161- 172
  13. 当間 忍 , 中島祥夫 . 痛みと運動機能. Clin Neurosci 1996; 14: 1028- 1030
  1. Shimizu, E., Shirasawa, H., Kodama, K., Koseki, K., Sato, T. and Simizu, B. (1995) Cloning and sequencing of the murine Mxi1 cDNA. Gene 152,283-284.
  2. Homma S. , Musha T, Nakajima Y, Okamoto Y, Blom S, Flink R, Hagbarth KE. . Conductivity ratios of the scalp-skull-brain head model in estimating equivalent dipole sources in human brain.. Neurosci Res 1995; 22: 51- 55
  3. Shiba K. , Yoshida K, Miura T. . Functional roles of the superior laryngeal nerve afferents in electrically induced vocalization in anesthetized cats.. Neurosci Res 1995; 22: 23- 30
  4. Takayama S. , Nakajima Y, Toma S, Sakamoto T. . Increased muscle sympathetic nerve activity after glucagon administration in man.. J Autonom Nerv Syst 1995; 54: 171- 175
  5. Toma S. , Shiozawa Z. . Amyotrophic cervical myelopathy in adolescence.. J Neurol Neurosurg Psychiatry 1995; 58: 56- 64
  6. Toma S. , Nakajima Y. . Response characteristics of cutaneous mechanoreceptors to vibratory stimuli in human glabrous skin.. Neurosci Lett 1995; 195: 61- 63
  7. 柴 啓介 , 吉田 耕、今野昭義 . 喉頭求心性入力がネコ誘発発声に及ぼす影響. 喉頭 1995; 7: 124- 132
  8. 中島祥夫 , 遊座 潤、坂本尚志、伊藤宏文、山中康久、新見将泰 . 発語に先行して記録された脳電位の解析. (鈴木英弘) EEG Topography 1991. 東京: 東京女子医大. 1995: 181- 190
  9. 中島祥夫 , . 脳機能解析の可能性:脳電位の双極子追跡法による電源推定. 先端医療 1995; 6: 32- 34
  10. 中島祥夫 , . 脳波による脳機能局在解析. 検査と技術 1995; 23: 159- 160
  11. 本間三郎 , 中島祥夫 . 運動ニューロンと錐体外路系. (石井威望、岡 博、岸本忠三、星 猛、和田 博) 新医科学大系 第7巻刺激の受容と生体運動. 東京: 中山書店. 1995: 223- 243
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