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2021

  1. Hagiya, M., Tanaka, T., Aita, K., Shiragami, R., Ihara, F., Ishii, A., Takami, M., Homma, T., Wada, Y., Motohashi, S.: Administration of α-galactosylceramide-pulsed Antigen Presenting Cells in Combination with First-line Chemotherapy for Advanced Lung Cancer. Chiba SurveyRes J. 10(1):27-33(2021).
  2. Ishii, A., Nasu, R., Motohashi, S.: Development of Chimeric Antigen Receptor T-Cell Therapy. Chiba SurveyRes J. 10(1):4-11(2021).
  3. Nakayama, T., Hirahara, K., Kimura, M.Y., Iwamura, C., Kiuchi, M., Kokubo, K., Onodera, A., Hashimoto, K., Motohashi, S.: CD4 + T cells in inflammatory diseases : pathogenic T-helper cells and the CD69-Myl9 system. Int Immunol. 33(12):699-704(2021).
  4. Shimazaki, R., Takano, S., Satoh, M., Takada, M., Miyahara, Y., Sasaki, K., Yoshitomi, H., Kagawa, S., Furukawa, K., Takayashiki, T., Kuboki, S., Sogawa, K., Motohashi, S., Nomura, F., Miyazaki, M., Ohtsuka, M.: Complement factor B regulates cellular senescence and is associated with poor prognosis in pancreatic cancer.Cell Oncol. 44(4):937-950(2021).

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2020

  1. Hara, A., Koyama-Nasu, R., Takami, M., Toyoda, T., Aoki, T., Ihara, F., Kobayashi, M., Hirono, S., Matsutani, T., Nakayama, T., Iwadate, Y., Motohashi, S.: CD1d expression in glioblastoma is a promising target for NKT cell-based cancer immunotherapy. Cancer Immunol. Immunother. 70(5):1239-1254(2020).
  2. Suzuki, A.S., Yagi, R., Kimura, M.Y., Iwamura, C., Shinoda, K., Onodera, A., Hirahara, K., Tumes, D. J., Koyama-Nasu, R., Iismaa, S. E., Graham, R. M., Motohashi, S., and Nakayama, T.: Essential role for CD30-Transglutaminase 2 axis in memory Th1 and Th17 cell generation. Front. Immunol. 11:1536 (2020).
  3. Hata, A., Suzuki, H., Nakajima, T., Fujiwara, T., Shiina, Y., Kaiho, T., Toyoda, T., Inage, T., Ito, T., Sakairi, Y., Tamura, H., Wada, H., Yamada, Y., Chiyo, M., Matsusaka, K., Fukuyo, M., Shinohara, KI., Itoga, S., Motohashi, S., Matsushita, K., Kaneda, A., and Yoshino, I.: Differential gene analysis during the development of obliterative bronchiolitis in a murine orthotopic lung transplantation model: a comprehensive transcriptome-based analysis.PLoS One. 15(5):e0232884(2020).
  4. Aoki, T., Takami, M., Takatani, T., Motoyoshi, K., Ishii, A., Hara, A., Toyoda, T., Okada, R., Hino, M., Koyama-Nasu, R., Kiuchi, M., Hirahara, K., Kimura, M.Y., Nakayama, T., Shimojo, N., and Motohashi, S.: Activated invariant natural killer T cells directly recognize leukemia cells in a CD1d-independent manner. Cancer Sci. 111(7):2223-2233(2020).
  5. Ishibashi, F., Sakairi, Y., Iwata, T., Moriya, Y., Mizobuchi, T., Hoshino, H., Yoshida, S., Hanaoka, H., Yoshino, I., and Motohashi, S.: A phase I study of loco-regional immunotherapy by trans-bronchial injection of α-galactosylceramide-pulsed antigen presenting cells in patients with lung cancer. Clin. Immunol. (2020).

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2019

  1. Suichi T, Misawa S, Beppu M, Takahashi S, Sekiguchi Y, Shibuya K, Amino H, Tsuneyama A, Suzuki Y, Nakamura K, Sato Y, Kuwabara S. Prevalence, clinical profiles, and prognosis of POEMS syndrome in Japanese nationwide survey. Neurology. 2019 Sep 3;93(10):e975-e983.
  2. Tumes, D., Hirahara, K., Papadopoulos, M., Shinoda, K., Onodera, A., Kumagai, J., Yip, KH., Pant, H., Kokubo, K., Masahiro, K., Aoki, A., Obata-Ninomiya, K., Yokoyoda, K., Endo, Y., Kimura, MY., Nakayama, T.: Ezh2 controls development of natural killer T cells that cause spontaneous asthma-like pathology. J Allergy Clin Immunol. (2019) 144(2):549-560.
  3. Suzuki S, Sakurai D, Sakurai T, Yonekura S, Iinuma T, Okuma Y, Ihara F, Arai T, Hanazawa T, Fukuda-Kawaguchi E, Ishii Y, Okamoto Y. Sublingual administration of liposomes enclosing alpha-galactosylceramide as an effective adjuvant of allergen immunotherapy in a murine model of allergic rhinitis. Allergol Int. 2019 ;68(3):352-362
  4. Nagao Y, Mimura N, Takeda J, Yoshida K, Shiozawa Y, Oshima M, Aoyama K, Saraya A, Koide S, Rizq O, Hasegawa Y, Shiraishi Y, Chiba K, Tanaka H, Nishijima D, Isshiki Y, Kayamori K, Kawajiri-Manako C, Oshima-Hasegawa N, Tsukamoto S, Mitsukawa S, Takeda Y, Ohwada C, Takeuchi M, Iseki T, Misawa S, Miyano S, Ohara O, Yokote K, Sakaida E, Kuwabara S, Sanada M, Iwama A, Ogawa S, Nakaseko C. Genetic and transcriptional landscape of plasma cells in POEMS syndrome. Leukemia. 2019 Jul;33(7):1723-1735
  5. Shibuya K, Tsuneyama A, Beppu M, Misawa S, Sekiguchi Y, Amino H, Suzuki YI, Suichi T, Nakamura K, Kuwabara S. A study supporting possible expression of inward-rectifying potassium channel 2.1 channels in peripheral nerve in a patient with Andersen-Tawil syndrome. Muscle Nerve. 2019 Apr;59(4):E28-E30.
  6. Shimizu F, Oishi M, Sawai S, Beppu M, Misawa S, Matsui N, Miyashiro A, Maeda T, Takeshita Y, Nishihara H, Sano Y, Sato R, Kaji R, Kuwabara S, Kanda T. Increased IP-10 production by blood-nerve barrier in multifocal acquired demyelinating sensory and motor neuropathy and multifocal motor neuropathy. J Neurol Neurosurg Psychiatry. 2019 Apr;90(4):444-450.
  7. Harada, K., Ihara, F., Takami, M., Kamata, T., Mise, N., Yoshizawa, H., Hishiki, T., Saito, T., Terui, K., Nakata, M., Komatsu, S., Ikeuchi, T., Nakayama, T., Yoshida, H., and Motohashi, S. : Soluble factors derived from neuroblastoma cell lines suppress dendritic cell differentiation and activation. Cancer Sci. 110(3): 888-902, 2019.
  8. Hamada H, Suzuki H, Onouchi Y, Ebata R, Terai M, Fuse S, Okajima Y, Kurotobi S, Hirai K, Soga T, Ishiguchi Y, Okuma Y, Takada N, Yanai M, Sato J, Nakayashiro M, Ayusawa M, Yamamoto E, Nomura Y, Hashimura Y, Ouchi K, Masuda H, Takatsuki S, Hirono K, Ariga T, Higaki T, Otsuki A, Terauchi M, Aoyagi R, Sato T, Fujii Y, Fujiwara T, Hanaoka H, Hata A; KAICA trial Investigators. Efficacy of primary treatment with immunoglobulin plus ciclosporin for prevention of coronary artery abnormalities in patients with Kawasaki disease predicted to be at increased risk of non-response to intravenous immunoglobulin (KAICA): a randomised controlled, open-label, blinded-endpoints, phase 3 trial. Lancet 393(10176):1128-1137. 2019.
  9. Hirahara, K., Shinoda, K., Morimoto, Y., Kiuchi, M., Aoki, A., Kumagai, J., Kokubo, K., and Nakayama, T.: Immune cell-epithelial/mesenchymal interaction contributing to allergic airway inflammation associated pathology. Front. Immunol. (2019) 10:570.
  10. Yokouchi H, Baba T, Misawa S, Oshitari T, Kuwabara S, Yamamoto S. Correlation of changes in serum level of VEGF and peripapillary retinal thickness in patients with POEMS syndrome. Br J Ophthalmol. 2019 Mar 26. pii: bjophthalmol-2018-313703.
  11. Wada, T., Hirahara, K., Aoki, A., Morimoto, Y., Kiuchi, M., Kumagai, J., Okano, M., Kokubo, K., Kato, M., Fukano, C., Ohashi-Doi, K., and Nakayama, T.: An Optimized protocol for the analysis of House dust mites (Dermatophagoides farinae) induced neutrophil-dominant airway inflammation with fibrosis. J. Immunol. Methods (2019) 465:53-60.
  12. Kuwabara S, Misawa S, Mori M. Atypical chronic inflammatory demyelinating polyneuropathies. J Neurol Neurosurg Psychiatry. 2019 Feb;90(2):121
  13. Suichi T, Misawa S, Sato Y, Beppu M, Sakaida E, Sekiguchi Y, Shibuya K, Watanabe K, Amino H, Kuwabara S. Proposal of new clinical diagnostic criteria for POEMS syndrome. J Neurol Neurosurg Psychiatry. 2019;90(2):133-137
  14. Shibuya K, Misawa S, Sekiguchi Y, Beppu M, Amino H, Suichi T, Suzuki YI, Tsuneyama A, Kuwabara S. Prodromal muscle cramps predict rapid motor functional decline in amyotrophic lateral sclerosis. J Neurol Neurosurg Psychiatry. 2019;90(2)242-243

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2018

  1. Takami, M., Cunha, C., Motohashi, S., Nakayama, T. and Iwashima, M.: TGF-β suppresses RasGRP1 expression and supports regulatory T cells resistance against p53-induced CD28-dependent T cell apoptosis. Eur. J. Immunol. 48(12):1938-1943, 2018.
  2. Makita, Y., Kunii, N., Sakurai, D., Ihara, F., Motohashi, S., Suzuki, A., Nakayama, T., and Okamoto, Y. : Activated iNKT cells enhance the anti-tumor effect of antigen specific CD8 T cells on mesothelin-expressing salivary gland cancer. BMC Cancer. 18(1):1254, 2018.
  3. Nishi T, Kitahara H, Fujimoto Y, Nakayama T, Nagashima K, Hanaoka H, Kobayashi Y. Intravenous nicorandil versus adenosine for fractional flow reserve measurement: crossover, randomized study. Heart Vessels 33(12):1570-1575. 2018.
  4. Makita Y, Naoki K, Sakurai D, Ihara F, Motohashi S, Suzuki A, Nakayama T, Okamoto Y. Activated iNKT cells enhance the antitumor effect of antigen specific CD8 T cells on mesothelin-expressing salivary gland cancer. BMC cancer. 2018; 18:1254.
  5. Mita, Y., Kimura, M.Y., Hayashizaki, K., Koyama-Nasu, R., Ito, T., Motohashi, S., Okamoto, Y., and Nakayama, T.: Crucial role of CD69 in anti-tumor immunity through regulating the exhaustion of tumor-in ltrating T cells. Int. Immunol. 30(12):559-567, 2018.
  6. Tanaka, T., Kanesaka, Y., Takami, M., Suzuki, A., Hosokawa, H., Onodera, A., Kamata, T., Nagato, K., Nakayama, T., and Yoshino, I., Motohashi, S.: Role of Leukotriene B4 12-Hydroxydehydrogenase in α-Galactosylceramide-Pulsed Dendritic Cell Therapy for Non-Small Cell Lung Cancer. Biochem. Biophys. Res. Commun. 506(1):27-32, 2018.
  7. Hirahara, K., Mato, N., Hagiwara, K., and Nakayama, T.: The pathogenicity of IL-33 on steroid-resistant eosinophilic inflammation via the activation of memory-type ST2+CD4+ T cells. 104(5):895-901. J Leukoc Biol. (2018).
  8. Furuya H, Ikeda K, Iida K, Suzuki K, Furuta S, Tamachi T, Suzuki K, Miura G, Hiraguri M, Hase R, Hikosaka K, Norose K, Nakajima H. Disseminated toxoplasmosis with atypical symptoms which developed with exacerbation of systemic lupus erythematosus. Lupus. 2018 Nov 28:961203318815583. doi: 10.1177/0961203318815583.
  9. Obata-Ninomiya, K., Ishiwata, K., Nakano, H., Endo, Y., Ichikawa, T., Onodera, A., Hirahara, K., Okamoto, Y., Kanuka, H., Nakayama, T.: CXCR6+ST2+ memory Th2 cells induced the expression of major basic protein in eosinophils to reduce the fecundity of helminth. Proc. Natl. Acad. Sci. USA (2018). Oct 16;115(42):E9849-E9858. doi: 10.1073/pnas.1714731115. Epub 2018 Oct 1.
  10. Yamamoto, T., Endo, Y., Onodera, A., Hirahara, K., Asou, H., Nakajima, T., Kanno, T., Ouchi, Y., Uematsu, S., Nishimasu, H., Nureki, O., Tumes, D. J., Shimojo, N., and Nakayama, T.: DUSP10 constrains innate IL-33-mediated cytokine production in ST2hi memory-type pathogenic Th2 cells. Nat. Commun. (2018). Oct 12;9(1):4231. doi: 10.1038/s41467-018-06468-8.
  11. Watanabe K, Hirano S, Kojima K, Nagashima K, Mukai H, Sato T, Takemoto M, Matsumoto K, Iimori T, Isose S, Omori S, Shibuya K, Sekiguchi Y, Beppu M, Amino H, Suichi T, Yokote K, Uno T, Kuwabara S, Misawa S. Altered cerebral blood flow in the anterior cingulate cortex is associated with neuropathic pain. J Neurol Neurosurg Psychiatry. 2018;89(10):1082-1087
  12. Sawada D, Fujii K, Misawa S, Shiohama T, Fukuhara T, Fujita M, Kuwabara S, Shimojo N. Bilateral spinal anterior horn lesions in acute motor axonal neuropathy. Brain Dev. 2018 Oct;40(9):830-832.
  13. Tanaka S, Suto A, Iwamoto T, Kageyama T, Tamachi T, Takatori H, Suzuki K, Hirose K, Ohara O, Lefebvre V, Nakajima H. Sox12 promotes T reg differentiation in the periphery during colitis. J Exp Med. 2018 Oct 1;215(10):2509-2519.
  14. Kimura, M. Y., Igi, A., Hayashizaki, K., Mita, Y., Shinzawa, M., Kadakia, T., Endo, Y., Ogawa, S., Yagi, R., Motohashi, S., Singer, A., Nakayama, T.: CD69 prevents PLZFhi innate precursors from prematurely exiting the thymus and aborting NKT2 cell differentiation. Nat. Commun. 9(1):3749, 2018.
  15. Takami, M., Ihara, F., and Motohashi, S.: Clinical Application of iNKT Cell-mediated Anti-tumor Activity Against Lung Cancer and Head and Neck Cancer. Front. Immunol. 7(9):2021, 2018.
  16. Ihara F, Sakurai D, Yonekura S, Iinuma T, Yagi R, Sakurai T, Ito T, Matsuura A, Morimoto Y, Arai T, Suzuki S, Katayama K, Nakayama T, Okamoto Y. Identification of specifically reduced Th2 cell subsets in allergic rhinitis patients after sublingual immunotherapy. Allergy. 2018 Mar 8.
  17. Kawajiri-Manako C, Mimura N, Fukuyo M, Namba H, Rahmutulla B, Nagao Y, Togasaki E, Shimizu R, Oshima-Hasegawa N, Tsukamoto S, Mitsukawa S, Takeda Y, Ohwada C, Takeuchi M, Iseki T, Misawa S, Yokote K, Tsuiji M, Kuwabara S, Sakaida E, Kaneda A, Nakaseko C. Clonal immunoglobulin λ light-chain gene rearrangements detected by next generation sequencing in POEMS syndrome. Am J Hematol. 2018 Sep;93(9):1161-1168.
  18. Makita S, Takatori H, Tamachi T, Suto A, Suzuki K, Nakajima H. Analyses of dermal innate lymphoid cells in mice lacking T-bet and STAT6. Allergol Int. 2018 Sep;67S:S51-S53.
  19. Sakurai, D., Uchida, R., Ihara, F., Kunii, N., Nakagawa, T., Chazono, H., Hanazawa, T., Motohashi, S., and Okamoto, Y.: Immunosuppressive property of submandibular lymph nodes in patients with head and neck tumors: differential distribution of regulatory T cells. BMC Res. Notes. 11(1):479, 2018.
  20. Ishibashi R, Takemoto M, Tsurutani Y, Kuroda M, Ogawa M, Wakabayashi H, Uesugi N, Nagata M, Imai N, Hattori A, Sakamoto K, Kitamoto T, Maezawa Y, Narita I, Hiroi S, Furuta A, Miida T, Yokote K. (2018) Immune-mediated acquired lecithin-cholesterol acyltransferase deficiency: A case report and literature review. J Clin Lipidol. 12, 888-897.
  21. Morimoto Y., Hirahara K., Kiuchi M., Wada T., Ichikawa T., Kanno T., Okano M., Kokubo K., Onodera A., Sakurai D., Okamoto Y., and Nakayama T.: Amphiregulin-producing pathogenic memory T helper-2 cells instruct eosinophils to secrete Osteopontin and facilitate airway fibrosis. 79(1):134-150. Immunity (2018).
  22. Sakurai D, Uchida R, Ihara F, Kunii N, Nakagawa T, Chazono H, Hanazawa T, Motohashi S, Okamoto Y. Immunosuppressive property of submandibular lymph nodes in patients with head and neck tumors: differential distribution of regulatory T cells. BMC Res Notes. 2018;11(1):479.
  23. Sakurai T, Yonekura S, Iinuma T, Sakurai D, Morimoto Y, Kaneko S, Okamoto Y. The Relationship of Pollen Dispersal with Allergy Symptoms and Immunotherapy: Allergen Immunotherapy Improves Symptoms in the Late Period of Japanese Cedar Pollen Dispersal. Int Arch Allergy Immunol. 2018 18 :1-10.
  24. Hirahara K, Shinoda K, Endo Y, Ichikawa T, Nakayama T: Maintenance of memory-type pathogenic Th2 cells in the pathophysiology of chronic airway inflammation. 38:10. doi: 10.1186/s41232-018-0067-8 Inflammation and Regeneration (2018).
  25. Misawa S, Kuwabara S, Sato Y, Yamaguchi N, Nagashima K, Katayama K, Sekiguchi Y, Iwai Y, Amino H, Suichi T, Yokota T, Nishida Y, Kanouchi T, Kohara N, Kawamoto M, Ishii J, Kuwahara M, Suzuki H, Hirata K, Kokubun N, Masuda R, Kaneko J, Yabe I, Sasaki H, Kaida KI, Takazaki H, Suzuki N, Suzuki S, Nodera H, Matsui N, Tsuji S, Koike H, Yamasaki R, Kusunoki S; Japanese Eculizumab Trial for GBS (JET-GBS) Study Group. Safety and efficacy of eculizumab in Guillain-Barré syndrome: a multicentre, double-blind, randomised phase 2 trial. Lancet Neurol. 2018;17(6):519-529.
  26. Kuwabara S, Misawa S, Mori M, Iwai Y, Ochi K, Suzuki H, Nodera H, Tamaoka A, Iijima M, Toda T, Yoshikawa H, Kanda T, Sakamoto K, Kusunoki S, Sobue G, Kaji R; Glovenin-I MMN Study Group. Intravenous immunoglobulin for maintenance treatment of multifocal motor neuropathy: A multi-center, open-label, 52-week phase 3 trial. J Peripher Nerv Syst. 2018;23(2):115-119
  27. Koda M, Hanaoka H, et al. Study protocol for the G-SPIRIT trial: a randomised, placebo-controlled, double-blinded phase III trial of granulocyte colony-stimulating factor-mediated neuroprotection for acute spinal cord injury. BMJ open 8(5):e019083, 2018.
  28. Yonekura S, Okamoto Y, Sakurai D, Okubo K, Gotoh M, Kaneko S, Konno A. An analysis of factors related to the effect of sublingual immunotherapy on Japanese cedar pollen induced allergic rhinitis. Allergol Int. 2018;67(2):201-208.
  29. Ohwada C, Sakaida E, Kawajiri-Manako C, Nagao Y, Oshima-Hasegawa N, Togasaki E, Muto T, Tsukamoto S, Mitsukawa S, Takeda Y, Mimura N, Takeuchi M, Shimizu N, Misawa S, Iseki T, Kuwabara S, Nakaseko C. Long-term evaluation of physical improvement and survival of autologous stem cell transplantation in POEMS syndrome. Blood. 2018 May 10;131(19):2173-2176.
  30. Hishiki, T., Mise, N., Harada, K., Ihara, F., Takami, M., Saito, T., Terui, K., Nakata, M., Komatsu, S., Yoshida, H., and Motohashi, S.: Frequency and proliferative response of circulating invariant natural killer T cells in pediatric patients with or without malignant solid tumors. Pediatr. Surg. Int. 34(2):169-176, 2018.
  31. Hishiki, T., Mise, N., Harada, K., Ihara, F., Takami, M., Saito, T., Terui, K., Nakata, M., Komatsu, S., Yoshida, H., and Motohashi, S.: Invariant natural killer T infiltration in neuroblastoma with favorable outcome. Pediatr. Surg. Int. 34(2):195-201, 2018.
  32. Nakagami H, Sugimoto K, Ishikawa T, Fujimoto T, Yamaoka T, Hayashi M, Kiyohara E, Ando H, Terabe Y, Takami Y, Yamamoto K, Takeya Y, Takemoto M, Koshizaka M, Ebihara T, Nakamura A, Nishikawa M, Yao XJ, Hanaoka H, Katayama I, Yokote K, Rakugi H. Physician-initiated clinical study of limb ulcers treated with a functional peptide, SR-0379: from discovery to a randomized, double-blind, placebo-controlled trial. NPJ Aging Mech. Dis. 4:2, 2018.
  33. Iinuma T, Okamoto Y, Morimoto Y, Arai T, Sakurai T, Yonekura S, Sakurai D, Hirahara K, Nakayama T.: Pathogenicity of memory Th2 cells is linked to stage of allergic rhinitis. Allergy 73(2):479-489. doi: 10.1111/all.13295. (2018).
  34. Arai T, Sakurai D, Iinuma T, Nakagawa T, Yonekura S, Okamoto Y. Basophils from allergic rhinitis patients show allergen-specific upregulation of thymic stromal lymphopoietin receptor. Ann Allergy Asthma Immunol. 2018;120(2):155-163.
  35. Kawashima, T., Ikari, N., Watanabe, Y., Kubota, Y., Motohashi, S., Shimojo, N., Tsuji, N. M.: Double-stranded RNA derived from lactic acid bacteria augments Th1 immunity via interferon-β from human dendritic cells. Front. Immunol. 9:27, 2018
  36. Sato D, Yoshinaga N, Nagai E, Hanaoka H, Sato Y, Shimizu E. Randomised controlled trial on the effect of internet-delivered computerised cognitive-behavioural therapy on patients with insomnia who remain symptomatic following hypnotics: a study protocol. BMJ Open 8(1):e018220. (2018)
  37. Goschl L, Preglej T, Hamminger P, Bonelli M, Andersen L, Boucherron N, Gulich A, Muller L, Saferding V, Mufazolov AI, Hirahara K, Seiser C, Matthias P, Penz T, Schuster M, Bock C, Waisman A, Steiner G, Ellmeier W.: A T cell-specific deletion of HDAC1 protects against experimental autoimmune encephalomyelitis. J Autoimmun. 86:51-61. doi: 10.1016/j.jaut.2017.09.008 (2018).
  38. Sekijima Y, Ueda M, Koike H, Misawa S, Ishii T, Ando Y. Diagnosis and management of transthyretin familial amyloid polyneuropathy in Japan: red-flag symptom clusters and treatment algorithm. Orphanet J Rare Dis. 2018 Jan 17;13(1):6.
  39. Kuroda M, Saito Y, Aso M, Yokote K. (2018) A novel approach to the treatment of plasma protein deficiency: Ex vivo-manipulated adipocytes for sustained secretion of therapeutic proteins. Chem. Pharm. Bull. 66, 217-224.
  40. Takami, M., Iwashima, M. and Motohashi, S.: Co-stimulatory Signaling Influences TGF-β-Dependent CD4+ T cell Differentiation and Its Plasticity. Chiba Survey Research Journal. 7(2): 80-87, 2018.

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2017

  1. Furuta, S., Sugiyama, T., Umibe, T., Kaneko, Y., Amano, K., Kurasawa, K., Nakagomi, D., Hiraguri, M., Hanaoka, H., Sato, Y., Ikeda, K., and Nakajima, H. : LoVAS Trial study investigators. Low-dose glucocorticoids plus rituximab versus high-dose glucocorticoids plus rituximab for remission induction in ANCA-associated vasculitis (LoVAS): protocol for a multicentre, open-label, randomised controlled trial. BMJ Open. 7(12):e018748 (2017).
  2. Yamazaki, S., Suzuki, T., Suzuki, T., Takatsuka, H., Ishikawaa, M., Hattori, N., Fujishiro, T., Miyauchi, H., Oami, T., Ariyoshi, N., Oda, S., Matsubara, H., and Ishii, I. : An extremely high bioavailability of orally administered vancomycin in a patient with severe colitis and renal insufficiency. J Infect Chemother. 23(12): 848-851 (2017).
  3. Nakayama, T., Hirahara, K., Onodera, A., Endo, Y., Hosokawa, H., Shinoda, K., Tumes, D. J., and Okamoto, Y. : Th2 cells in health and disease. Annu Rev Immunol. 35: 53-84 (2017).
  4. Ito, T., Hirahara, K., Onodera, A., Koyama-Nasu, R., Yano, I., and Nakayama, T. : Anti-tumor immunity via the superoxide-eosinophil axis induced by lipophilic component of Mycobacterium lypomannan. Int Immunol. 29(9):411-421 (2017).
  5. Nakagawa, T., Matsusaka, K., Misawa, K., Ota, S., Takane, K., Fukuyo, M., Rahmutulla, B., Shinohara, KI., Kunii, N., Sakurai, D., Hanazawa, T., Matsubara, H., Nakatani, Y., Okamoto, Y., and Kaneda, A. : Frequent promoter hypermethylation associated with human papillomavirus infection in pharyngeal cancer. Cancer Lett. 18;407:21-31 (2017).
  6. Kuwabara, S., Mori, M., Misawa, S., Suzuki, M., Nishiyama, K., Mutoh, T., Doi, S., Kokubun, N., Kamijo, M., Yoshikawa, H., Abe, K., Nishida, Y., Okada, K., Sekiguchi, K., Sakamoto, K., Kusunoki, S., Sobue, G., Kaji, R., and Glovenin-I CIDP Study Group. : Intravenous immunoglobulin for maintenance treatment of chronic inflammatory demyelinating polyneuropathy: a multicentre, open-label, 52-week phase III trial. J Neurol Neurosurg Psychiatry 88(10):832-838 (2017).
  7. Kageyama, T., Suto, A., Iwamoto, T., Tanaka, S., Suehiro, K., Yokoyama, Y., Saku, A., Furuta, S., Ikeda, K., Suzuki, K., Hirose, K., and Nakajima, H. : IL-21 Exacerbates Autoimmune Myositis by Enhancing the Accumulation of GM-CSF–Producing γδ T Cells in the Muscle. ImmunoHorizons. 1(8):176-187 (2017).
  8. Ihara, F., Sakurai, D., Horinaka, A., Fujisawa, A., Makita, Y., Sakurai, T., Yamasaki, K., Kunii, N., Motohashi, S., Nakayama, T. and Okamoto, Y. : CD45RA-Foxp3high regulatory T cells have a negative impact on the clinical outcome of head and neck squamous cell carcinoma. Cancer Immunol Immunother. 66(10):1275-85(2017).
  9. Kuwabara, S., Mori, M., Misawa, S., Suzuki, M., Nishiyama, K., Mutoh, T., Doi, S., Kokubun, N., Kamijo, M., Yoshikawa, H., Abe, K., Nishida, Y., Okada, K., Sekiguchi, K., Sakamoto, K., Kusunoki, S., Sobue, G. and Kaji, R. and Glovenin-I CIDP Study Group. : Intravenous immunoglobulin for maintenance treatment of chronic inflammatory demyelinating polyneuropathy: a multicentre, open-label, 52-week phase III trial. J Neurol Neurosurg Psychiatry. 88(10):832-838(2017).
  10. Onodera A, Kiuchi M, Kokubo K, Kato M, Ogino T, Horiuchi S, Kanai U, Hirahara K, Nakayama T. : Menin controls the memory Th2 cell function by maintaining the epigenetic integrity of Th2 cells. J Immunol. 1;199(3):1153-1162 (2017).
  11. Omori, S., Isose, S., Misawa, S., Watanabe, K., Sekiguchi, Y., Shibuya, K., et al. : Pain-related evoked potentials after intraepidermal electrical stimulation to Adelta and C fibers in patients with neuropathic pain. Neurosci Res. 121:43-48 (2017).
  12. Kimura, M. Y., Hayashizaki, K., Tokoyoda, K., Takamura, S., Motohashi, S., and Nakayama, T.: Crucial role for CD69 in allergic inflammatory responses: CD69-Myl9 system in the pathogenesis of airway inflammation. Immunol Rev. 278(1):87-100 (2017).
  13. Ogasawara, S., Chiba, T., Ooka, Y., Kanogawa, N., Motoyama, T., Suzuki, E., Tawada, A., Nagai, K., Nakagawa, T., Sugawara, T., Hanaoka, H., Kanai, F., and Yokosuka, O. : A Randomized Placebo-Controlled Trial of Prophylactic Dexamethasone for Transcatheter Arterial Chemoembolization. Hepatology. doi: 10.1002/hep.29403 (2017).
  14. Shinoda, K., Hirahara, K., and Nakayama, T. : Maintenance of pathogenic Th2 cells in allergic disorders. Allergol. Int. 66(3):369-376 (2017).
  15. Tumes, D. J., Papadopoulos, M., Endo, Y., Onodera, A., Hirahara, K., and Nakayama, T. : Epigenetic regulation of T helper cell differentiation, memory and plasticity in allergic asthma. Immunol Rev. 278(1):8-19 (2017).
  16. Mato, N., Hirahara, K., Ichikawa, T., Kumagai, J., Nakayama, M., Yamasawa, H., Bando, M., Hagiwara, K., Sugiyama, Y., and Nakayama, T. : Memory-type ST2+CD4+ T cells participate in the steroid-resistant pathology of eosinophilic pneumonia. Sci Rep. 28;7(1):6805 (2017).
  17. Yokota, M., Tamachi, T., Yokoyama, Y., Maezawa, Y., Takatori, H., Suto, A., Suzuki, K., Hirose, K., Takeda, K., and Nakajima, H. : IκBNS induces Muc5ac expression in epithelial cells and causes airway hyper-responsiveness in murine asthma models. Allergy. 72(7):1043-1053 (2017).
  18. Hosokawa, J., Suzuki, K., Meguro, K., Tanaka, S., Maezawa, Y., Suto, A., Fujimura, L., Sakamoto, A., Clevers, H., Ohara, O., and Nakajima, H. : IκBNS enhances T follicular helper cell differentiation and function as downstream of Ascl2. J Allergy Clin Immunol. 140(1):288-291.e8 (2017).
  19. Yonekura, S., Okamoto, Y., Sakurai, D., Sakurai, T., Iinuma, T., Yamamoto, H., Hanazawa, T., Horiguchi, S., Kurono, Y., Honda, K., Majima, Y., Masuyama, K., Takeda, N., Fujieda, S., Okano, M., Ogino, S. and Okubo, K. : Complementary and alternative medicine for allergic rhinitis in Japan. Allergol Int. 66(3):425-431 (2017).
  20. Sugibayashi, K. and Ishii, I. : Thorough Discussion! What Does IPE Bring to Pharmaceutical Education?. Yakugaku Zasshi. 137(7):845 (2017).
  21. Okubo, M., Takahashi, Y., Yamashita, J., Takahashi, H., Miyata, O., Suzuki, T. and Ishii, I. : In Practical Training, a Questionnaire Survey and Analysis to Pharmacy Students of the Utilization Situation of the Course Contents of Pharmacy School. Yakugaku Zasshi. 1;137(6):745-755 (2017).
  22. Iwata, S., Mikami, Y., Sun, HW., Brooks, RS., Jankovic, D., Hirahara, K., Onodera, A., Shih, HY., Kawabe, T., Jiang, K., Nakayama, T., Sher, A., O’Shea, JJ., Davis, FP. and Kanno, Y. : The transcription factor T-bet limits amplification of type l IFN transcriptome and circuitry in T helper 1 cells. Immunity. 46(6):983-991.e4 (2017).
  23. Yokouchi, H., Baba, T., Misawa, S., Kitahashi, M., Oshitari, T., Kuwabara, S., et al. : Changes in subfoveal choroidal thickness and reduction of serum levels of vascular endothelial growth factor in patients with POEMS syndrome. Br J Ophthalmol. 101(6):786-790 (2017).
  24. Nishi, T., Ariyoshi, N., Nakayama, T., Fujimoto, Y., Sugimoto, K., Wakabayashi, S., Hanaoka, H., and Kobayashi, Y. : Impact of chronic kidney disease on platelet inhibition of clopidogrel and prasugrel in Japanese patients. J Cardiol. 69(5):752-755 (2017).
  25. Iwase, T., Yokouchi, H., Misawa, S., Oshitari, T., Baba, T., Kuwabara, S., and Yamamoto, S. : Reduction of Optic Disc Oedema by Bortezomib and Dexamethasone Followed by Autologous Peripheral Blood Stem Cell Transplantation in Patient with POEMS Syndrome. Neuroophthalmology. 19;42(1):25-30 (2017).
  26. Matsuki, A., Takatori, H., Makita, S., Yokota, M., Tamachi, T., Suto, A., Suzuki, K., Hirose, K., and Nakajima, H. : T-bet inhibits innate lymphoid cell-mediated eosinophilic airway inflammation by suppressing IL-9 production. J Allergy Clin Immunol. 139(4):1355-1367 (2017).
  27. Natori, T., Fujiyoshi, M., Uchida, M., Abe, N.,Kanaki, T., Fukumoto, Y. and Ishii, I. : Growth Arrest of Vascular Smooth Muscle Suspension Culture Using Low-Acyl Gellan Gum. In Vitro Cell Dev Biol Anim. 53(3):191-198 (2017).
  28. Brück, J., Holstein, J., Glocova, I., Seidel, U., Geisel, J., Kanno, T., Kumagai, J., Mato, N., Sudowe, S., Widmaier, K., Sinnberg, T., Yazdi, AS., Eberle, FC., Hirahara, K., Nakayama, T., Röcken, M. and Ghoreschi, K. : Nutrional control of IL-23/Th17-mediated autoimmune disease through HO-1/STAT3 activation. Sci Rep. 2017 Mar 14;7:44482. doi: 10.1038/srep44482. (2017).
  29. Watanabe, E., Yamazaki, S., Setoguchi, D., Sadahiro, T., Tateishi, Y., Suzuki, T., Ishii, I. and Oda, S. : Pharmacokinetics of Standard- and Reduced-Dose Recombinant Human Soluble Thrombomodulin in Patients with Septic Disseminated Intravascular Coagulation during Continuous Hemodiafiltration. Front Med (Lausanne). 21;4:15. 00015. eCollection (2017).
  30. Muto, T., Ohwada, C., Takaishi, K., Isshiki, Y., Nagao, Y., Hasegawa, N., Kawajiri-Manako, C., Togasaki, E., Shimizu, R., Tsukamoto, S., Sakai, S., Takeda, Y., Mimura, N., Takeuchi, M., Sakaida, E., Misawa, S., Shimizu, N., Iseki, T., Kuwabara, S. and Nakaseko, C. : Safety and Efficacy of Granulocyte Colony-Stimulating Factor Monotherapy for Peripheral Blood Stem Cell Collection in POEMS Syndrome. Biol Blood Marrow Transplant. 23(2):361-3 (2017).
  31. Beppu, M., Sawai, S., Misawa, S., Mori, M., Ito S, Sogawa, K., et al. : Serum cytokine and chemokine profiles in patients with juvenile muscular atrophy of distal upper extremity (Hirayama disease). J Neuroimmunol. 302:20-2 (2017).

▲TOP

2016

  1. Kamata, T., Suzuki, A., Mise, N., Ihara, F., Takami, T., Makita, Y., Horinaka, A., Harada, K., Kunii, K., Yoshida, S., Yoshino, I., Nakayama, T. and Motohashi, S. : Blockade of Programmed Death-1/Programmed Death Ligand pathway enhances the antitumor immunity of human invariant Natural Killer T cells. Cancer Immunol Immunother. 65(12):1477-1489 (2016).
  2. Hirahara, K., Schwartz, D., Gadina, M., Kanno, Y. and O’Shea, JJ. : Targeting cytokine signaling in autoimmunity: back to the future and beyond. Curr Opin Immunol. 43:89-97 (2016).
  3. Yamaguchi, N., Misawa, S., Sato, Y., Nagashima, K., Katayama, K., Sekiguchi, Y., Iwai, Y., Amino, H., Suichi, T., Yokota, T., Nishida, Y., Kohara, N., Hirata, K., Nishiyama, K., Yabe, I., Kaida, KI., Suzuki, N., Nodera, H., Tsuji, S., Koike, H., Kira, JI., Hanaoka, H., Kusunoki, S., Kuwabara, S. and JET-GBS Group. : A Prospective, Multicenter, Randomized Phase II Study to Evaluate the Efficacy and Safety of Eculizumab in Patients with Guillain-Barré Syndrome (GBS): Protocol of Japanese Eculizumab Trial for GBS (JET-GBS). JMIR Res Protoc. 5(4):e210 (2016).
  4. Nishi, T., Kitahara, H., Fujimoto, Y., Nakayama, T., Sugimoto, K., Nagashima, K., Hanaoka, H. and Kobayashi, Y. : Efficacy of intravenous nicorandil for fractional flow reserve assessment: study protocol for a crossover randomised trial. BMJ Open. 6(11):e012737 (2016).
  5. Poudel, BK. and Ishii, I. Hospital pharmacy service in developing nations: The case of Nepal. 12(6):1038-39 (2016).
  6. Tanino, A., Okura, T., Nagao, T., Kukida, M., Enomoto, D., Miyoshi, K., Higaki, J., Kuroda, M. and Bujo, H. : A case of acquired lecithin:cholesterol acyltransferase deficiency with sarcoidosis that remitted spontaneously. CEN Case Rep. 5, 1-5 (2016).
  7. Nakayama, T., Endo, Y., Shinoda, K. and Hirahara, K. : Pathogenic Th cell subsets in chronic inflammatory diseases. Cornea. 35:S8 (2016).
  8. Yamaguchi, N., Misawa, S., Sato, Y., Nagashima, K., Katayama, K., Sekiguchi, Y., et al. : A Prospective, Multicenter, Randomized Phase II Study to Evaluate the Efficacy and Safety of Eculizumab in Patients with Guillain-Barre Syndrome (GBS): Protocol of Japanese Eculizumab Trial for GBS (JET-GBS). JMIR Res Protoc. 5(4):e210 (2016).
  9. Kanogawa, Y., Fujiyoshi, M., Nakazato, Y., Watanabe, K., Kurihara, M., Takezawa, A., Uchida, M., Igarashi, K., Suzuki, T., Ariyoshi, N. and Ishii, I. : Beta-migrating very low-density lipoprotein conjugates with acrolein in high-cholesterol diet-fed rabbits and localizes to atherosclerotic lesions with macrophages. Int J Clin Expe Path. 9(11):11149-58 (2016).
  10. Misawa, S., Sato, Y., Katayama, K., Nagashima, K., Aoyagi, R., Sekiguchi, Y., Sobue, G., Koike, H., Yabe, I., Sasaki, H., Watanabe, O., Takashima, H., Nishizawa, M., Kawachi, I., Kusunoki, S., Mitsui, Y., Kikuchi, S., Nakashima, I., Ikeda, S., Kohara, N., Kanda, T., Kira, J., Hanaoka, H. and Kuwabara, S. : Japanese POEMS Syndrome for Thalidomide (J-POST) Trial Study Group. Safety and efficacy of thalidomide in patients with POEMS syndrome: a multicentre, randomised, double-blind, placebo-controlled trial. Lancet Neurol. 15(11):1129-1137 (2016).
  11. Misawa, S., Sato, Y., Katayama, K., Nagashima, K., Aoyagi, R., Sekiguchi, Y., et al. : Safety and efficacy of thalidomide in patients with POEMS syndrome: a multicentre, randomised, double-blind, placebo-controlled trial. Lancet Neurol. 15(11):1129-37 (2016).
  12. Hayashizaki, K., Kimura, MY., Tokoyoda, K., Hosokawa, H., Shinoda, K., Hirahara, K., Ichikawa, T., Onodera, A., Hanazawa, A., Iwamura, C., Kakuta, J., Muramoto, K., Motohashi, S., Tumes, DJ., Iinuma, T., Yamamoto, H., Ikehara, Y., Okamoto, Y. and Nakayama, T. : Myosin light chain 9 and 12 are functional ligands for CD69 that regulate airway inflammation. Sci. Immunol. 1(3): pp.eaaf9154 (2016).
  13. Sakurai, D., Yonekura, S., Iinuma, T., Sakurai, T., Morimoto, Y., Mita, Y., Arai, T., Suzuki, S., Okuma, Y., Kaneko, S. and Okamoto, Y. : Sublingual immunotherapy for allergic rhinitis: subjective versus objective tools to evaluate its success. Rhinology. 54(3):221-30 (2016).
  14. Aoki, T., Hino, M., Koh, K., Kyushiki, M., Kishimoto, H., Arakawa, Y., Hanada, R., Kawashima, H., Kurihara, J., Shimojo, N. and Motohashi. : Low Frequency of Programmed Death Ligand 1 Expression in Pediatric Cancers. Pediatr. Blood Cancer. 63(8):1461-4 (2016).
  15. Kosaka, K., Kubota, Y., Adachi, N., Akita, S., Sasahara, Y., Kira, T., Kuroda, M., Mitsukawa, N., Bujo, H., and Satoh K. : Human Adipocytes from the Subcutaneous Superficial Layer have Greater Adipogenic Potential and Lower PPAR-γ DNA Methylation Levels than Deep Layer Adipocytes. Am J Physiol Cell Physiol. 311, C322-329 (2016).
  16. Okuma, Y., Okamoto, Y., Yonekura, S., Iinuma, T., Sakurai, T., Hamasaki, S., Ohki, Y., Yamamoto, H. and Sakurai, D. : Persistent nasal symptoms and mediator release after continuous pollen exposure in an environmental challenge chamber. Ann Allergy Asthma Immunol. 117(2):150-7 (2016).
  17. Yokouchi, H., Baba, T., Misawa, S., Sawai, S., Kitahashi, M., Oshitari, T., et al. : Correlation between peripapillary retinal thickness and serum level of vascular endothelial growth factor in patients with POEMS syndrome. Br J Ophthalmol. 100(7):897-901 (2016).
  18. Iwai, Y., Shibuya, K., Misawa, S., Sekiguchi, Y., Watanabe, K., Amino, H., et al. : Axonal Dysfunction Precedes Motor Neuronal Death in Amyotrophic Lateral Sclerosis. PLoS One. 11(7):e0158596 (2016).
  19. Poudel, BK. and Ishii I. : Assessment of physical premises of selected pharmacies of Nepal. SAGE Open Med. eCollection Res Social Adm Pharm. (2016).
  20. Suzuki, T., Okamoto, Y., Yonekura, S., Okuma, Y., Sakurai, T. and Sakurai, D. : Characteristics of laryngeal symptoms induced in patients with allergic rhinitis in an environmental challenge chamber. Ann Allergy Asthma Immunol. 116(6):491-6 (2016).
  21. Sekiguchi, Y., Mori, M., Misawa, S., Sawai, S., Yuki, N., Beppu, M., et al. : How often and when Fisher syndrome is overlapped by Guillain-Barre syndrome or Bickerstaff brainstem encephalitis?. Eur J Neurol. 23(6):1058-63 (2016).
  22. Tanemura, N., Uyama, Y., Nagashima, K., Suzuki, T., Asahina, Y., Kobayashi, Y., Iyo, M., Yokote, Y. and Hanaoka, H. : Comparison of Drug Use Between Clinical Practice and Regulatory Approval: Results in Older Japanese Patients With Rheumatoid Arthritis, Diabetes, High Blood Pressure, or Depression. Ther Innov Regul Sci. 50(6): 743-750 (2016).
  23. Yoshinaga, N., Matsuki, S., Niitsu, T., Sato, Y., Tanaka, M., Ibuki, H., Takanashi, R., Ohshiro, K., Ohshima, F., Asano, K., Kobori, O., Yoshimura, K., Hirano, Y., Sawaguchi, K., Koshizaka, M., Hanaoka, H., Nakagawa, A., Nakazato, M., Iyo, M. and Shimizu, E. : Cognitive Behavioral Therapy for Patients with Social Anxiety Disorder Who Remain Symptomatic following Antidepressant Treatment: A Randomized, Assessor-Blinded, Controlled Trial. Psychother Psychosom. 85(4):208-217 (2016).
  24. 黒田正幸、武城英明、麻生雅是、齋藤康、横手幸太郎. 疾患治療用タンパク質分泌加工脂肪細胞の創薬開発と難病治療. 薬学雑誌-Symposium Review- 136; 705-709 (2016).
  25. Shinoda, K., Hirahara, K., Iinuma, T., Ichikawa, T., Suzuki, A., Sugaya, K., Tumes, DJ., Yamamoto, H., Hara, T., Tani-ichi, S., Ikuta, K., Okamoto, Y. and Nakayama, T. : Thy1+IL-7+ lymphatic endthelial cells in iBALT provide a survival niche for memory T-helper cells in allergic airway inflammation. Proc Natl Acad Sci U S A. 113(20):E2842-E2851 (2016).
  26. Hosokawa, H., Tanaka, T., Endo, Y., Kato, M., Shinoda, K., Suzuki, A., Motohashi, S., Matsumoto, M., Nakayama, K. I. and Nakayama, T. : Akt1-mediated Gata3 phosphorylation controls the repression of IFNγ in memory-type Th2 cells. Nat Commun. 7:11289 (2016).
  27. Hirahara, K. and Nakayama, T. : CD4+ T cell subsets in inflammatory diseases: beyond the Th1/Th2 paradigm. Int Immunol. 28(4):163-71 (2016).
  28. Eberle, FC., Bruck, J., Holstein, J., Hirahara, K. and Ghoreschi, K. : Recent advances in understanding prosiasis. F1000Res, 2016 Apr 28;5. Pii: F1000 Faculty Rev-770 (2016)
  29. Bonelli, M., Goschl, L., Bluml, S., Karonitsch, T., Hirahara, K., Ferner, E., Steiner, CW., Steiner, G., Smolen, JS. and Scheinecker, C. : Abatacept (CTLA-4Ig) treatment reduces T cell apoptosis and regulatory T cell suppression in patients with rheumatoid arthritis. Rheumatology (Oxford). 55(4):710-20 (2016).
  30. Muto, T., Ohwada, C., Sawai, S., Beppu, M., Tsukamoto, S., Takeda, Y., Mimura, N., Takeuchi, M., Sakaida, E., Sogawa, K., Misawa, S., Shimizu, N., Iseki, T., Nomura, F., Kuwabara, S. and Nakaseko, C. : Acutely deteriorated extravascular volume overload during peripheral blood stem cell mobilization in POEMS syndrome: A case series with cytokine analysis. Transfus Apher Sci. 54(2):276-81 (2016).
  31. Araki, N., Misawa, S., Shibuya, K., Ota, S., Oide, T., Kawano, A., et al. : POEMS syndrome and calciphylaxis: an unrecognized cause of abnormal small vessel calcification. Orphanet J Rare Dis. 11:35 (2016).
  32. Horinaka, A., Sakurai, D., Ihara, F., Makita, Y., Kunii, N., Motohashi, S., Nakayama, T. and Okamoto, Y. : Invariant NKT cells are resistant to circulating CD15(+) myeloid-derived suppressor cells in patients with head and neck cancer. Cancer Sci. 107(3):207-16 (2016).
  33. Mise, N., Takami, M., Suzuki, A., Kamata, T., Harada, K., Hishiki, T., Saito, T., Terui, K., Mitsunaga, T., Nakata, M., Ikeuchi, T., Nakayama, T., Yoshida, H. and Motohashi, S. : Antibody-dependent cellular cytotoxicity toward neuroblastoma enhanced by activated invariant NKT cells. Cancer Sci. 107(3):233-41 (2016).
  34. Meguro, K., Nakagomi, D., Suzuki, K., Hosokawa, J., Fukuta, T., Yokota, M., Maezawa, Y., Suto, A. and Nakajima, H. SOCS3 Expressed in M2 Macrophages Attenuates Contact Hypersensitivity by Suppressing MMP-12 Production. J Invest Dermatol. 136:649-57 (2016).
  35. Mitsuhashi, A., Sato, Y., Kiyokawa, T., Koshizaka, M., Hanaoka, H. and Shozu, M. Phase II study of medroxyprogesterone acetate plus metformin as a fertility-sparing treatment for atypical endometrial hyperplasia and endometrial cancer. Ann Oncol. 27(2):262-266 (2016).
  36. Masuyama, K., Goto, M., Takeno, S., Ohta, N., Okano, M., Kamijo, A., Suzuki, M., Terada, T., Sakurai, D., Horiguchi, S., Honda, K., Matsune, S., Yamada, T., Sakashita, M., Yuta, A., Fuchiwaki, T., Miyanohara, I., Nakayama, T., Okamoto, Y. and Fujieda, S. : Guiding principles of sublingual immunotherapy for allergic rhinitis in Japanese patients. Auris Nasus Larynx. 43(1):1-9 (2016).
  37. Jain, R., Chen, Y., Kanno, Y., Joyce-Shaikh, B., Vahedi, G., Hirahara, K., Blumenschein, WM., Sukumar, S., Haines, CJ., Sadekova, S., McClanahan, TK., McGeachy, MJ., O’Shea, JJ., Cua, DJ. Interleukin-23-Induced Transcription Factor Blimp-1 Promotes pathogenicity of T Helper 17 Cells. Immunity. 19;44(1):131-42 (2016).
  38. Uchida, M., Suzuki, S., Suzuki, T. and Ishii, I. : p27(Kip1) and p21(Cip1)-independent proliferative inhibition of vascular smooth muscle cells cultured in type-I collagen matrix honeycombs. Microvasc Res. 103:36-40 (2016).

▲TOP

2015

  1. Miasma, S., Sato, Y., Katayama, K., et al. : Vascular endothelial growth factor as a predictive marker for POEMS syndrome treatment response: retrospective cohort study. BMJ Open. 5(11):e009157 (2015).
  2. Suto, A., Tanaka, S. and Nakajima, H. : Sox5 and Th17 cell differentiation. Oncotarget. 6(24):19952-3 (2015).
  3. Hirahara, K., Onodera, A., Villario, AV., Bonelli, M., Sciumè, G., Laurence, A., Sun, HW., Brooks, RS., Vahedi, G., Shih, HY., Gutierrez-Cruz, G., Iwata, S., Suzuki, R., Miami, Y., Okamoto, Y., Wakayama, T., Holland, S., Hunter, CA., Kanno, Y. and O’Shea, JJ. : Asymmetric action of STAT transcription factors drives transcriptional outputs and cytokine specificity. Immunity. 42(5):877-89 (2015).
  4. Frigault, M. J., Lee, J., Basil, M., Carpenito, C., Motohashi, S., Scholler, J., Kawalekar, O. U., Guedan, S., McGettigan, S., Posey, A Jr., Ang, S., Cooper, L. J., Platt, J., Johnson, F. B., Paulos, C. M., Zhao, Y., Kalos, M., Milone, M. and June, C. H. : Identification of chimeric antigen receptors that mediate constitutive or inducible proliferation of T cells. Cancer Immunol Res. 3(4):356-367 (2015).
  5. Ishii, I. and Uchida, M. : Three-Dimensional “Honeycomb” Culture System that Helps to Maintain the Contractile Phenotype of Vascular Smooth Muscle Cells. Muscle Cell and Tissue", book edited by Kunihiro Sakuma, ISBN 978-953-51-2156-5 (2015).
  6. Matsumoto, J., Ariyoshi, N., Sakakibara, M., Nakanishi, T., Okubo, Y., Shiina, N., Fujisaki, K., Nagashima, T., Nakanishi, Y., Tamai, I., Yamada, H., Takeda, H. and Ishii, I. : Organic anion transporting polypeptide 2B1 expression vcorrelates with uptake of estrone-3-sulfate and cell proliferation in estrogen receptor-positive breast cancer cells. Drug Metab Pharmacokinet. 30(2):133-41 (2015).
  7. Horinaka, A., Sakurai, D., Ihara, F., Makita, Y., Kunii, N., Motohashi, S., Nakayama, T. and Okamoto, Y. : Invariant NKT cells are resistant to circulating CD15+ myeloid-derived suppressor cells in patients with head and neck cancer. Cancer Sci. 107(3):207-16 (2015).
  8. Katayama, K., Misawa, S., Sato, Y., et al. : Japanese POEMS syndrome with Thalidomide (J-POST) Trial: study protocol for a phase II/III multicentre, randomised, double-blind, placebo-controlled trial. BMJ Open. 5(1):e007330 (2015).

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