研究室について

これまでの実績

2018年 (total impact fac.85.231 ave. 7.748)

Endo, Y., Onodera, A., Obata-Ninomiya, K., Koyama-Nasu, R., Asou, H. K., Ito, T., Yamamoto, T., Kanno, T., Nakajima, T., Ishiwata, K., Kanuka, H., Tumes, D. J., and Nakayama, T.: Acc1 determines memory potential of indivisual CD4+ T cells by regulating de novo fatty acid biosynthesis. Nat. Metab. in press.

Onodera, A., Kokubo, K., and Nakayama, T.: Epigenetic and transcriptional regulation in the induction, maintenance, heterogeneity, and recall-response of effector and memory Th2 cells. Front. Immunol. in press. (5.511)

Tokuhara, D., Kurashima, Y., Kamioka, M., Nakayama, T., Ernst, P., and Kiyono, H.: A comprehensive understanding of the gut mucosal immune system in allergic inflammation. Allergol. Int. in press. (4.045)

Takami, M., Cunha, C., Motohashi, S., Nakayama, T., and Iwashima, M.: TGF-β suppresses RasGRP1 expression and supports regulatory T cell resistance against p53-induced CD28-dependent T-cell apoptosis. Eur. J. Immunol. 48:1938-1943 (2018). (4.248)

Tanaka, K., Kanesaka, Y., Takami, M., Suzuki, A., Hosokawa, H., Onodera, A., Kamata, T., Nagato, K., Nakayama, T., Yoshino, I., and Motohashi, S.: Role of leukotriene B4 12-hydroxydehydrogenase in α-galactosylceramide-pulsed dendritic cell therapy for non-small cell lung cancer. Biochem. Biophys. Res. Commun. 506:27-32 (2018). (2.559)

Mita, Y., Kimura, M. Y., Hayashizaki, K., Koyama-Nasu, R., Ito, T., Motohashi, S., Okamoto, Y., and Nakayama, T.: Crucial role of CD69 in anti-tumor immunity through regulating the exhaustion of tumor-infiltrating T cells. Int. Immunol. 30:559-567 (2018). (5.189)

Yamamoto, T., Endo, Y., Onodera, A., Hirahara, K., Asou, H. K., Nakajima, T., Kanno, T., Ouchi, Y., Uematsu, S., Nishimasu, H., Nureki, O., Tumes, D. J., Shimojo, N., and Nakayama, T.: DUSP10 constrains IL-33-mediated cytokine production in ST2hi memory-type pathogenic Th2 cells. Nat. Commun. 9:4231 (2018). (12.353)

Obata-Ninomiya, K., Ishiwata, K., Nakano, H., Endo, Y., Ichikawa, T., Onodera, A., Hirahara, K., Okamoto, Y., Kanuka, H., and Nakayama, T.: CXCR6+ST2+ memory Th2 cells induced the expression of major basic protein in eosinophils to reduce the fecundity of helminth. Proc. Natl. Acad. Sci. USA 115:E9849-E9858 (2018). (9.504)

Hirahara, K., Mato, N., Hagiwara, K., and Nakayama, T.: The pathogenicity of IL-33 on steroid-resistant eosinophilic inflammation via the activation of memory-type ST2+CD4+ T cells. J. Leukoc. Biol. 104:895-901 (2018). (4.224)

Kimura, M. Y., Igi, A., Hayashizaki, K., Mita, Y., Shinzawa, M., Kadakia, T., Endo, Y., Ogawa, S., Yagi, R., Motohashi, S., Singer, A., and Nakayama, T.: CD69 prevents PLZFhi innate precursors from prematurely exiting the thymus and aborting NKT2 cell differentiation. Nat. Commun. 9:3749 (2018). (12.353)

Iwamura, C., and Nakayama, T.: Role of CD1d- and MR1-restricted T cells in asthma. Front. Immunol. 9:1942(2018). (5.511)

Morimoto, Y., Hirahara, K., Kiuchi, M., Wada, T., Ichikawa, T., Kanno, T., Okano, M., Kokubo, K., Onodera, A., Sakurai, D., Okamoto, Y., and Nakayama, T.: Amphiregulin-producing pathogenic memory T helper-2 cells instruct eosinophils to secrete Osteopontin and facilitate airway fibrosis. Immunity 49:134-150 (2018). (19.734)

Onodera, A., Kokubo, K., and Nakayama, T.: The interplay between transcription factors and epigenetic modifications in Th2 cells. Gene Expression and Regulation in Mammalian Cells -Transcription from General Aspects Edited by Fumiaki Uchiumi 191-211 (2018).

Lian, S. L., Mihi, B., Koyanagi, M., Nakayama, T., and Bix, M.: A SNP uncoupling Mina expression from the TGFβ signaling pathway. Immun. Inflamm. Dis. 6:58-71 (2018).