研究室について

これまでの実績

2019年

Tumes, D., Hirahara, K., Papadopoulos, M., Shinoda, K., Onodera, A., Kumagai, J., Yip, K. H., Pant, H., Kokubo, K., Kiuchi, M., Aoki, A., Obata-Ninomiya, K., Tokoyoda, K., Endo, Y., Kimura, M. Y., and Nakayama, T.: Ezh2 controls development of natural killer T cells, which cause spontaneous asthma-like pathology. J. Allergy Clin. Immunol. 144(2):549-560.e10 (2019).

Hirahara, K., Aoki, A., Morimoto, Y., Kiuchi, M., Okano, M., and Nakayama, T.: The immunopathology of lung fibrosis: amphiregulin-producing pathogenic memory T helper-2 cells control the airway fibrotic responses by inducing eosinophils to secrete osteopontin. Semin. Immunopathol. 41(3):339-348 (2019).

Hirahara, K., Shinoda, K., Morimoto, Y., Kiuchi, M., Aoki, A., Kumagai, J., Kokubo, K., and Nakayama, T.: Immune cell-epithelial/mesenchymal interaction contributing to allergic airway inflammation associated pathology. Front. Immunol. 10:570 (2019).

Pillai, M. R., Mihi, B., Ishiwata, K., Nakamura, K., Sakuragi, N., Finkelstein, D. B., McGargill, M. A., Nakayama, T., Ayabe, T., Coleman, M. L., and Bix, M.: Myc-induced nuclear antigen constrains a latent intestinal epithelial cell-intrinsic anthelmintic pathway. PLoS ONE 14:e0211244 (2019).

Harada, K., Ihara, F., Takami, M., Kamata, T., Mise, N., Yoshizawa, H., Hishiki, T., Saito, T., Terui, K., Nakata, M., Komatsu, S., Ikeuchi, T., Nakayama, T., Yoshida, H., and Motohashi, S.: Soluble factors derived from neuroblastoma cell lines suppress dendritic cell differentiation and activation. Cancer Sci. 110:888-902 (2019).

Endo, Y., Onodera, A., Obata-Ninomiya, K., Koyama-Nasu, R., Asou, H. K., Ito, T., Yamamoto, T., Kanno, T., Nakajima, T., Ishiwata, K., Kanuka, H., Tumes, D. J., and Nakayama, T.: Acc1 determines memory potential of indivisual CD4+ T cells by regulating de novo fatty acid biosynthesis. Nat. Metab. 1:261-275 (2019).

Kameoka, Y., Kishi, F., Koura, M., Yamakawa, Y., Nagasawa, R., Ito, F., Matsuda, J., Suzuki, O., Nakayama, T., and Suzuki, K.: Efficacy of a recombinant single-chain fragment variable region, VasSF, as a new drug for vasculitis. Drug Des. Devel. Ther. 13:555-568 (2019).

Wada, T., Hirahara, K., Aoki, A., Morimoto, Y., Kiuchi, M., Kumagai, J., Okano, M., Kokubo, K., Kato, M., Fukano, C., Ohashi-Doi, K., and Nakayama, T.: An Optimized protocol for the analysis of house dust mite (Dermatophagoides farinae)-induced neutrophil-dominant airway inflammation. J. Immunol. Methods 465:53-60 (2019).

Tokuhara, D., Kurashima, Y., Kamioka, M., Nakayama, T., Ernst, P., and Kiyono, H.: A comprehensive understanding of the gut mucosal immune system in allergic inflammation. Allergol. Int. 68:17-25 (2019).