研究室について

これまでの実績

2013年 (total impact fac. 139.921 ave. 9.328)

Fujii, S., Shimizu, K., Okamoto, Y., Kunii, N., Nakayama, T., Motohashi, S., and Taniguchi, M.: NKT cells as an ideal anti-tumor immunotherapeutic. Front. Immunol. 4:409 (2013).

Nakamura, T., Fukiage, M., Higuchi, M., Nakaya, A., Yano, I., Miyazaki, J., Nishiyama, H., Akaza, H., Ito, T., Hosokawa, H., Nakayama, T., and Harashima, H.: Nanoparticulation of BCG-CWS for application to bladder cancer therapy. J. Control. Release 176:44-53 (2013). (7.633)

Tumes, D. J., Onodera, A., Suzuki, A., Shinoda, K., Endo, Y., Iwamura, C., Hosokawa, H., Koseki, H., Tokoyoda, K., Suzuki, Y., Motohashi, S., and Nakayama, T.: The polycomb protein Ezh2 regulates differentiation and plasticity of CD4+ T helper type-1 and type-2 cells. Immunity 39:819-832 (2013). (19.795)

Hosokawa, H., Tanaka, T., Kato, M., Shinoda, K., Tohyama, H., Hanazawa, A., Tamaki, Y., Hirahara, K., Yagi, R., Sakikawa, I., Morita, A., Nagira, M., Poyurovsky, M. V., Suzuki, Y., Motohashi, S., and Nakayama, T.: Gata3/Ruvbl2 complex regulates T helper 2 cell proliferation via repression of Cdkn2c expression. Proc. Natl. Acad. Sci. USA 110:18626-18631 (2013). (9.737)

Suzuki, K., Suzuki, K., Nagao, T., and Nakayama, T.: Proposal of anti-moesin as a novel biomarker for ANCA-associated vasculitis. Clin. Exp. Nephrol. 17:638-641 (2013). (1.246)

Nagao, T., Kusunoki, R., Iwamura, C., Kobayashi, S., Yumura, W., Kameoka, Y., Nakayama, T., and Suzuki, K.: Correlation of Interleukin-6 and monocyte chemotactic protein-1 concentrations with crescent formation and myeloperoxidase-specific anti-neutrophil cytoplasmic antibody titer in SCG/Kj mice by treatment with anti-interleukin-6 receptor antibody or Mizoribine. Microbiol. Immunol. 57:640-650 (2013). (1.545)

Hanazawa, A., Hayashizaki, K., Shinoda, K., Yagita, H., Okumura, K., Lohning, M., Hara, T., Tani-ichi, S., Ikuta, K., Eckes, B., Radbruch, A., Tokoyoda, K., and Nakayama, T.: CD49b-dependent establishment of T helper cell memory. Immunol. Cell Biol. 91:524-531 (2013). (3.925)

Homma, T., Kinugawa, S., Takahashi, M., Sobirin, M. A., Saito, A., Fukushima, A., Suga, T., Takada, S., Kadoguchi, T., Masaki, Y., Furihata, T., Taniguchi, M., Nakayama, T., Ishimori, N., Iwabuchi, K., and Tsutsui, H.: Activation of invariant natural killer T cells by α-galactosylceramide ameliorates myocardial ischemia/reperfusion injury in mice. J. Mol. Cell. Cardiol. 62:179-188 (2013). (5.148)

Sasaki, T., Onodera, A., Hosokawa, H., Watanabe, Y., Horiuchi, S., Yamashita, J., Tanaka, H., Ogawa, Y., Suzuki, Y., and Nakayama, T.: Genome-wide gene expression profiling revealed a critical role for GATA3 in the maintenance of the Th2 cell identity. PLOS ONE 8:e66468 (2013). (3.73)

Yamashita, J., Iwamura, C., Ito, T., Narita, M., Hara, Y., Sasaki, T., Masuda, D., Takahashi, M., Tsuchiya, M., Hada, K., Ishikawa, M., Matsuo, T., Ohno, Y., Tanaka, H., Maruyama, H., Ogawa, Y., and Nakayama, T.: Paraoxonase-1 suppresses experimental colitis via the inhibition of IFN-γ production from CD4 T cells. J. Immunol. 191:949-960 (2013). (5.52)

Hasegawa, A., Iwamura, C., Kitajima, M., Hashimoto, K., Otsuyama, K., Ogino, H., Nakayama, T., and Shirai, M.: Crucial role for CD69 in the pathogenesis of dextran sulphate sodium-induced colitis. PLOS ONE 8:e65494 (2013). (3.73)

Jabara, H. H., Ohsumi, T., Chou, J., Massaad, M. J., Benson, H., Megarbane, A., Chouery, E., Mikhael, R., Gorka, O., Gewies, A., Portales, P., Nakayama, T., Hosokawa, H., Revy, P., Herrod, H., Le Deist, F., Lefranc, G., Ruland, J., and Geha, R. S.: A homozygous mucosa-associated lymphoid tissue 1 (MALT1) mutation in a family with combined immunodeficiency. J. Allergy Clin. Immunol. 132:151-158 (2013). (12.047)

Suzuki, J., Kuwahara, M., Tofukuji, S., Imamura, M., Kato, F., Nakayama, T., Ohara, O., and Yamashita, M.: A novel small compound SH-2251 suppresses Th2 cell-dependent airway inflammation through selective modulation of chromatin status at the Il5 gene locus. PLOS ONE 8(4):e61785 (2013). (3.73)

Hosokawa, H., Tanaka, T., Suzuki, Y., Iwamura, C., Ohkubo, S., Endoh, K., Kato, M., Endo, Y., Onodera, A., Tumes, D. J., Kanai, A., Sugano, S., and Nakayama, T.: Functionally distinct Gata3/Chd4 complexes coordinately establish T helper 2 (Th2) cell identity. Proc. Natl. Acad. Sci. USA 110:4691-4696 (2013). (9.737)

Mucida, D., Husain, M. M., Muroi, S., van Wijk, F., Shinnakasu, R., Naoe, Y., Reis, B. S., Huang, Y., Lambolez, F., Docherty, M., Attinger, A., Shui, J. W., Kim, G., Lena, J. C., Sakaguchi, S., Miyamoto, C., Wang, P., Atarashi, K., Park, Y., Nakayama, T., Honda, K., Ellmeier, W., Kronenberg, M., Taniuchi, I., and Cheroutre, H.: Transcriptional reprogramming of mature CD4+ helper T cells generates distinct MHC class II-restricted cytotoxic T lymphocyets. Nat. Immunol. 14:281-289 (2013). (26.199)

Onodera, A., Tumes, D. J., and Nakayama, T.: Too much of a good thing. Nat. Immunol. 14:112-114 (2013). (26.199)