DEPARTMENT OF IMMUNOLOGY, GRADUATE SCHOOL OF MEDICINE, CHIBA UNIVERSITY

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About us

Ongoing Projects

Generation and maintenance of immune system

  • Regulation of memory CD4 T cell (Th1/Th2/Th17) generation and maintenance
  • Epigenetic regulation of memory T cell differentiation by Polycomb and Trithorax complex molecules
  • Establishment of T cell-dependent immune system in the thymus and periphery

Generation and maintenance of Pathogenic Immunological Memory and its regulaton

  • Summary of Grant-in-aid for Scientific Research S (2014.5-2019.3)
  • Summary of Grant-in-aid for Scientific Research S (2019.6-2024.3)
  • Pathogenic Th cell regulation of chronic airway inflammation in mouse and human system
  • Role for CD69/CD69L (Myl9) in the pathogenesis of inflammatory diseases and cancer in mouse and human system

Past Projects

Development of NKT cell-mediated immunotheraphy for cancer

  • Targeted immunotheraphy for lung cancer
  • Targeted immunotheraphy for head and neck cancer

Generation and maintenance of immune system

  • Molecular mechanisms of memory Th1/Th2 cells' differentiation and function, the 2nd round (2010-)
  • Roles of CD69 molecules in immunoregulation
  • Gata3 genes and regulation of Type 2 immune response
  • Th2 cell differentiation and chromatin remodeling of the Th2 cytokine gene loci
  • TCR-mediated signal transduction that regulates Th1/Th2 cell differentiation
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Department of Immunology, Graduate School of Medicine, Chiba University